Results 221 to 230 of about 65,609 (259)
Readiness Level of Spanish Labs to Detect Mpox Clade Ib: A Nationwide EQA
Journal of Medical Virology, Volume 98, Issue 5, May 2026.ABSTRACT To assess the preparedness and diagnostic capacity of Spanish clinical microbiology laboratories to detect the emerging monkeypox virus (MPXV) Clade Ib through a nationwide external quality assessment. A blinded 16‐sample panel (serum and DNA eluates) containing MPXV Clade Ib, Clade II, vaccinia, and negatives was distributed.
Adolfo De Salazar +49 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.ABSTRACT Liver transplantation (LT) is the standard treatment for end‐stage liver disease, yet the gap between the demand for organs and their availability is widening. In Taiwan, the scarcity of deceased donor organs highlights the need for optimized utilization strategies.
Jie‐Lan Jhang +11 more
wiley +1 more source
CAR‐T Cells: Current Status, Challenges, and Future Prospects
MedComm, Volume 7, Issue 5, May 2026.This graphical abstract outlines the current status, challenges, and future prospects of CAR‐T cells. The biological basis of CAR‐T cell therapy is the elegant redirection of adaptive immunity. Its initial successes have exposed a landscape of multifaceted challenges.
Aya Sedky Adly +6 more
wiley +1 more source
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Journal of NeuroVirology, 2023
The diagnosis of progressive multifocal leukoencephalopathy (PML) is based on a combination of clinical, radiographic, and laboratory findings. However, negative JC polyomavirus (JCPyV) PCR in CSF does not always rule out JCPyV-related PML. In this narrative review, we sought to examine the characteristic of biopsy-proven PML in patients with ...
Chia-Yu Chiu +4 more
openaire +2 more sources
The diagnosis of progressive multifocal leukoencephalopathy (PML) is based on a combination of clinical, radiographic, and laboratory findings. However, negative JC polyomavirus (JCPyV) PCR in CSF does not always rule out JCPyV-related PML. In this narrative review, we sought to examine the characteristic of biopsy-proven PML in patients with ...
Chia-Yu Chiu +4 more
openaire +2 more sources
Journal of Infection, 2014
Polyomaviruses are ubiquitous, species-specific viruses belonging to the family Papovaviridae. The two most commonly known human polyomaviruses, BK virus and JC virus were first described in the 1970s. Newer human polyomaviruses, namely KI polyoma virus, WU polyoma virus and Merkel cell polyoma virus were identified in the last five years.
Michelle, Pinto, Simon, Dobson
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Polyomaviruses are ubiquitous, species-specific viruses belonging to the family Papovaviridae. The two most commonly known human polyomaviruses, BK virus and JC virus were first described in the 1970s. Newer human polyomaviruses, namely KI polyoma virus, WU polyoma virus and Merkel cell polyoma virus were identified in the last five years.
Michelle, Pinto, Simon, Dobson
openaire +2 more sources
Atypical presentations and course of JC virus infection
Journal of NeuroVirology, 2022There is increasing evidence that the spectrum of human polyomavirus 2 (JCV) CNS disease includes novel syndromes other than progressive multifocal leukoencephalopathy (PML), the appreciation of which is increasingly important in the context of MS therapies and immunodeficiency states. Our objective is to describe unusual presentations of JCV infection
Sophie Chatterton +7 more
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Role of the Environment in the Transmission of JC Virus
Journal of Neurovirology, 2003JC virus is etiologically associated with a fatal demyelinating disease known as PML. JCV produces persistent infections in the kidney and is excreted in the urine of healthy individuals and in the urine of PML patients. The characteristics of the JCV excreted in the environment have been studied by analyzing sewage samples from divergent geographical ...
Sílvia, Bofill-Mas, Rosina, Girones
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Revisiting JC virus and progressive multifocal leukoencephalopathy
Journal of NeuroVirology, 2023Since its definition 65 years ago, progressive multifocal leukoencephalopathy (PML) has continued to devastate a growing population of immunosuppressed patients despite major advances in our understanding of the causative JC virus (JCV). Unless contained by the immune system, JCV lyses host oligodendrocytes collateral to its life cycle, leading to ...
Angela Rocchi +2 more
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JC virus in human glial-derived tumors
Human Pathology, 2000To investigate the presence and the role of polyomaviruses JC (JCV), BK (BKV), and the simian polyomavirus (SV40) in human brain tumors, samples from 25 glial-derived tumors (10 astrocytomas, 5 ependymomas, 5 oligodendrogliomas, and 5 glioblastomas) were examined by means of molecular biology and immunohistochemistry.
R, Caldarelli-Stefano +5 more
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No association of JC virus with Alzheimer's disease or astrocytomas
Clinical and Diagnostic Virology, 1995To investigate if JC virus (JCV) can be involved in the pathogenesis of Alzheimer's disease (AD) and astrocytomas.A nested polymerase chain reaction (PCR) was used for the detection of JCV DNA in autopsy brain material (cerebral white matter) and cerebrospinal fluid (CSF) specimens from patients with AD and age-matched control patients without ...
G, Bogdanovic +6 more
openaire +2 more sources