Results 211 to 220 of about 65,609 (259)
DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy
Advanced Science, Volume 13, Issue 26, 8 May 2026.Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi +12 more
wiley +1 more source
Advanced Science, Volume 13, Issue 26, 8 May 2026.A series of Fe2+/viscosity cascade‐activated NIR fluorescence probes (NP1–5) are synthesized, and NP3 is selected for its optimal properties. To verify application of NP3 in ferroptosis intervention in PD, PQR NPs, is constructed by NP3 and quercetin self‐assembling.
Lixia Guo +11 more
wiley +1 more source
The Effect of Ocrelizumab on Anti‐JC Virus Antibody Index
Brain and Behavior, Volume 16, Issue 5, May 2026.Synopsis: This study of 553 MS patients found that anti‐JC virus (JCV) antibody indices remain stable during the first 2 years of ocrelizumab treatment. While peripheral B‐cells were significantly depleted and serum immunoglobulins (IgG, IgM, IgA) showed modest declines, the JCV antibody index did not change significantly.
Akash Virupakshaiah +8 more
wiley +1 more source
Can Immune Checkpoint Inhibitors Keep JC Virus in Check? [PDF]
N Engl J Med, 2019 Koralnik IJ.
europepmc +1 more source
Clinical &Translational Immunology, Volume 15, Issue 5, 2026.Abstract Objectives CD4+ T cells play key roles in regulating immune responses during pregnancy; therefore, we aimed to understand the CD4+ T‐cell surface proteome and transcriptome during pregnancy. Methods CD4+ T cells were analysed in blood and decidua from term pregnancies (> 37 weeks) and non‐pregnant blood.
Jennifer R Habel +17 more
wiley +1 more source
Haemoglobin A1c Time‐In‐Range and Mortality in Adults With Diabetes
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.Reduced A1c time in range and particularly greater time below range are associated with increased mortality in adults with diabetes. A1c stability within person‐specific ranges may be a risk predictor for major outcomes in adults with diabetes. ABSTRACT Introduction Glycemic variability over time is a risk factor for diabetes complications.
Paul R. Conlin +8 more
wiley +1 more source
European Journal of Immunology, Volume 56, Issue 5, May 2026.This study showed dysregulated αβ T cell homeostasis with ongoing T cell activation and low‐grade inflammation in 5‐12‐year‐old CHD children who underwent early‐life cardiac surgery with thymectomy, characterized by reduced naïve T cells and increased memory/effector and senescent‐like T cells.
Yusuf Eshimutu Abu +13 more
wiley +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.ABSTRACT Objective To assess whether antivirals are associated with a reduced incidence of uveitis following COVID‐19. Methods We conducted a multi‐institutional, population‐based retrospective cohort study of adults (≥ 18 years) diagnosed with COVID‐19 between 2022 and 2024. Patients who received antiviral agents (Paxlovid, Molnupiravir, or Remdesivir)
Hou‐Ting Kuo +14 more
wiley +1 more source
International Journal of Cancer, Volume 158, Issue 9, Page 2298-2308, 1 May 2026.What's new? This large nation‐wide cohort study provides a comprehensive 20‐year analysis of cancer trends among people living with HIV in France, highlighting persistent excess risks for virus‐related cancers despite effective antiretroviral therapy and immune restoration.
Sophie Grabar +14 more
wiley +1 more source
Antenatal Presentation of MRPS22‐Related Mitochondrial Disease Confirmed With Rapid Proteomics
JIMD Reports, Volume 67, Issue 3, May 2026.ABSTRACT MRPS22‐related mitochondrial disease (MIM#611719) is a rare autosomal recessive disorder caused by defects in the mitochondrial ribosomal protein S22, a component of the small mitoribosomal subunit essential for mitochondrial translation. Of the few reported cases, most present antenatally with a severe phenotype, conveying a poor prognosis ...
Liana N. Semcesen +43 more
wiley +1 more source