Results 211 to 220 of about 66,683 (260)

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

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BK and JC virus: A review

Journal of Infection, 2014
Polyomaviruses are ubiquitous, species-specific viruses belonging to the family Papovaviridae. The two most commonly known human polyomaviruses, BK virus and JC virus were first described in the 1970s. Newer human polyomaviruses, namely KI polyoma virus, WU polyoma virus and Merkel cell polyoma virus were identified in the last five years.
Michelle, Pinto, Simon, Dobson
openaire   +2 more sources

Undetectable JC virus CSF PCR in patients with JC virus-induced progressive multifocal leukoencephalopathy

Journal of NeuroVirology, 2023
The diagnosis of progressive multifocal leukoencephalopathy (PML) is based on a combination of clinical, radiographic, and laboratory findings. However, negative JC polyomavirus (JCPyV) PCR in CSF does not always rule out JCPyV-related PML. In this narrative review, we sought to examine the characteristic of biopsy-proven PML in patients with ...
Chia-Yu Chiu, Eva Amenta, Violeta Chavez, Yuriko Fukuta, Rodrigo Hasbun   +4 more
openaire   +2 more sources

Role of the Environment in the Transmission of JC Virus

Journal of Neurovirology, 2003
JC virus is etiologically associated with a fatal demyelinating disease known as PML. JCV produces persistent infections in the kidney and is excreted in the urine of healthy individuals and in the urine of PML patients. The characteristics of the JCV excreted in the environment have been studied by analyzing sewage samples from divergent geographical ...
Sílvia, Bofill-Mas, Rosina, Girones
openaire   +2 more sources

Revisiting JC virus and progressive multifocal leukoencephalopathy

Journal of NeuroVirology, 2023
Since its definition 65 years ago, progressive multifocal leukoencephalopathy (PML) has continued to devastate a growing population of immunosuppressed patients despite major advances in our understanding of the causative JC virus (JCV). Unless contained by the immune system, JCV lyses host oligodendrocytes collateral to its life cycle, leading to ...
Angela Rocchi, Ilker K. Sariyer, Joseph R. Berger   +2 more
openaire   +2 more sources

JC virus in human glial-derived tumors

Human Pathology, 2000
To investigate the presence and the role of polyomaviruses JC (JCV), BK (BKV), and the simian polyomavirus (SV40) in human brain tumors, samples from 25 glial-derived tumors (10 astrocytomas, 5 ependymomas, 5 oligodendrogliomas, and 5 glioblastomas) were examined by means of molecular biology and immunohistochemistry.
R, Caldarelli-Stefano, R, Boldorini, G, Monga, E, Meraviglia, E O, Zorini, P, Ferrante   +5 more
openaire   +2 more sources

Molecular prevalence of JC virus in Tehran, Iran.

Gastroenterology and hepatology from bed to bench, 2012
Since data about prevalence of JC virus in Iranian population is scarce, this study was designed to evaluate the prevalence of JC virus in healthy individuals who had attended Fajr hospital and Farjam clinical laboratory in Tehran, Iran.JC virus is the causative agent of progressive multifocal encephalopathy (PML) in individuals with suppressed immune ...
Majidizadeh Bozorgi, Sajjad, Tahaei, Seyed Mohammad Ebrahim, Mohebbi, Seyed Reza, Sahba, Negar, Damavand, Behzad, Romani, Sara, Azimzadeh, Pedram, Naghoosi, Hamed, Milanizadeh, Saman, Mohebbi, Abolfazl, Zali, Mohammad Reza   +10 more
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JC Virus

Nihon rinsho. Japanese journal of clinical medicine, 2003
Joseph Berger, Eugene Major, Bruce Sabath   +2 more
openaire   +3 more sources

Chromatin mimicry by human JC virus

Chronically persistent viruses are integral components of the organismal ecosystem in humans and animals 1 2 . Many of these viruses replicate and accumulate within the cell nucleus 3 .
Uwe Schaefer, Yekaterina A. Miroshnikova, Wei Xie, Adam G. Larson, Ziyu Lu, Shoudeng Chen, Martina Bradic, Yehuda Goldgur, Kexin Chen, Ved P. Sharma, Junyue Cao, Dinshaw J. Patel, Geeta J. Narlikar, Sara A. Wickström, Alexander Tarakhovsky   +14 more
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JC virus leukoencephalopathy complicating Wegener’s granulomatosis

Joint Bone Spine, 2003
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the brain caused by the JC virus. It occurs in association with immunodepression due, for instance, to a hematological malignancy, HIV infection, or immunosuppressive therapy for an organ transplant or systemic disease.
Christian, Pagnoux, Gilles, Hayem, Fabienne, Roux, Sid Ahmed, Rouidi, Elizabeth, Palazzo, Dominique, Hénin, Olivier, Meyer   +6 more
openaire   +2 more sources