Results 21 to 30 of about 65,024 (264)
Oligosaccharides as Receptors for JC Virus [PDF]
Journal of Virology, 2002 ABSTRACT JC virus (JCV) belongs to the polyomavirus family of double-stranded DNA viruses and in humans causes a demyelinating disease of the central nervous system, progressive multifocal leukoencephalopathy. Its hemagglutination activity and entry into host cells have been reported to depend on an N-linked glycoprotein containing sialic ...
Rika, Komagome +6 more
openaire +2 more sources
Jc Virus-Induced Progressive Multifocal Leukoencephalopathy [PDF]
Future Virology, 2010 Progressive multifocal encephalopathy (PML) is a fatal demyelinating disease of the central nervous system (CNS), caused by the lytic infection of oligodendrocytes by a human polyomavirus, JC virus (JCV). PML is rare disease but mostly develops in patients with underlying immunosuppressive conditions, including Hodgkin's lymphoma, lymphoproliferative ...
A Sami, Saribas +3 more
openaire +2 more sources
Progressive multifocal leukoencephalopathy: new concepts
Arquivos de Neuro-Psiquiatria, 2013 Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the CNS caused by reactivation of JC virus (JCV) in a setting of cellular immunosuppression.
Marco A. Lima
doaj +1 more source
T' Proteins Influence JC Virus Biology [PDF]
Journal of Neurovirology, 2003 The JC virus early mRNA is alternatively spliced to yield five transcripts that encode large T antigen, small t antigen, T'(135), T'(136), and T'(165). The splicing process is regulated differentially in transformed versus lytically infected cells and temporally during the course of a productive infection. The authors have identified a potential exonic
Richard J, Frisque +3 more
openaire +2 more sources
Vaccines, 2023 Foot-and-mouth disease (FMD) is a fatal contagious viral disease that affects cloven-hoofed animals and causes severe economic damage at the national level.
Seong Yun Hwang +6 more
doaj +1 more source
JC Virus Infection of the Brain [PDF]
American Journal of Neuroradiology, 2010 Since its initial description, there have been significant changes in the epidemiology, pathogenesis, and clinical and imaging manifestations of JCV infection of brain. The most common clinical manifestation is PML. Other recently described CNS manifestations are JCE, JCVGCN, and JCM.
A K, Bag +4 more
openaire +2 more sources
JC Virus Agnoprotein Colocalizes with Tubulin [PDF]
Journal of Neurovirology, 2003 The human polyomavirus JC (JCV) encodes an agnoprotein that consists of 71 amino acid residues, with a molecular weight of approximately 8 kDa, from the late protein coding region. The agnoprotein of JCV shares 50% to 60% homology with those of simian virus 40 (SV40) and BK virus (BKV), and the carboxyl-terminal region of JCV agnoprotein is relatively ...
Shuichi, Endo +6 more
openaire +2 more sources
Journal of Global Infectious Diseases, 2016 Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by polyomavirus John Cunningham (JC) virus.
Tanmay S Panchabhai +4 more
doaj +1 more source
Polymerase chain reaction for the laboratory diagnosis of aseptic meningitis and encephalitis [PDF]
Arquivos de Neuro-Psiquiatria, 2000 A protocol for testing cerebrospinal fluid specimens using a range of PCR assays for the diagnosis of central nervous system infection was developed and used to test prospectively 383 specimens.
MARISA CHESKY +4 more
doaj +1 more source
AIDS-related progressive multifocal leukoencephalopathy
Revista da Sociedade Brasileira de Medicina Tropical, 2020 INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).
Carolina de Oliveira Abrão +5 more
doaj +1 more source