Results 51 to 60 of about 246,780 (358)
Association between the JC polyomavirus infection and male infertility. [PDF]
PLoS ONE, 2012 In recent years the incidence of male infertility has increased. Many risk factors have been taken into consideration, including viral infections. Investigations into viral agents and male infertility have mainly been focused on human papillomaviruses ...
Manola Comar +12 more
doaj +1 more source
Enhancement of the Critical Current Density of YBa2Cu3Ox Superconductors under Hydrostatic Pressure [PDF]
Phys. Rev. Lett. 96, 077001 (2006), 2005 The dependence of the critical current density Jc on hydrostatic pressure to 0.6 GPa is determined for a single 25-degree [001]-tilt grain boundary in a bicrystalline ring of nearly optimally doped melt-textured YBa2Cu3Ox. Jc is found to increase rapidly under pressure at +20 %/GPa. A new diagnostic method is introduced (pressure-induced Jc relaxation)
arxiv +1 more source
Frontiers in Immunology, 2018 The increased use of newer potent immunomodulatory therapies for multiple sclerosis (MS), including natalizumab, fingolimod, and dimethyl fumarate, has expanded the patient population at risk for developing progressive multifocal leukoencephalopathy (PML)
Elizabeth A. Mills +2 more
doaj +1 more source
Role of JC Virus Agnoprotein in DNA Repair [PDF]
Journal of Virology, 2004 ABSTRACTThe late region of human neurotropic JC virus encodes a small 71-amino-acid agnoprotein that is also found in the polyomaviruses simian virus 40 and BK virus. Several functions of agnoprotein have been identified, including roles in regulating viral transcription and virion maturation.
Armine Darbinyan +6 more
openaire +3 more sources
Therapeutic Advances in Neurological Disorders, 2021 Progressive multifocal leukoencephalopathy (PML) is a subacute brain infection by the opportunistic John Cunningham (JC) virus. Herein, we describe seven patients with PML, lymphopenia, and sarcoidosis, in three of whom PML was the first manifestation of
Maike F. Dohrn +8 more
doaj +1 more source
p53 Inhibits JC Virus DNA Replicationin Vivoand Interacts with JC Virus Large T-Antigen
Virology, 1996 The onset of DNA replication is an important step within the life cycle of the human neurotropic polyomavirus JC. In this report, evidence that both the human and the murine tumor suppressor protein p53 strongly inhibit JCV DNA replication in vivo is presented.
Josef-Karl Gerber +6 more
openaire +3 more sources
Neutron irradiation of coated conductors [PDF]
Supercond. Sci. Technol. 23 (2010) 014009, 2009 Various commercial coated conductors were irradiated with fast neutrons in order to introduce randomly distributed, uncorrelated defects which increase the critical current density, Jc, in a wide temperature and field range. The Jc-anisotropy is significantly reduced and the angular dependence of Jc does not obey the anisotropic scaling approach. These
arxiv +1 more source
A case of progressive multifocal leukoencephalopathy in a HIV-infected female patient [PDF]
Терапевтический архив, 2016 Progressive multifocal leukoencephalopathy (PML) caused by JC virus is a severe central nervous lesion developing in the presence of obvious immunodeficiency. In most cases, the disease results in a fatal outcome within a few months.
E A Samotolkina +4 more
doaj +1 more source
Fatal ruxolitinib-related JC virus meningitis
Journal of NeuroVirology, 2017 We report a possible association between ruxolitinib and JC virus meningitis. A 72-year-old man with myelofibrosis started treatment with ruxolitinib. Fourteen days later, the patient presented to the emergency department with fever and nausea. HIV test was negative. Ruxolitinib was suspended.
Ballesta, Begoña +3 more
openaire +5 more sources
Self-organized critical dynamics of RNA virus evolution [PDF]
arXiv, 2022 RNA virus (e.g., SARS-CoV-2) evolves in a complex manner. Studying RNA virus evolution is vital for understanding molecular evolution and medicine development. Scientists lack, however, general frameworks to characterize the dynamics of RNA virus evolution directly from empirical data and identify potential physical laws. To fill this gap, we present a
arxiv