Results 41 to 50 of about 33,016,997 (287)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Work Engagement and Job Crafting of Brazilian Professionals [PDF]

open access: yesRevista Psicologia, 2020
The job demands-resources (JD-R) model explains the relationships between job demands and (job and personal) resources as well as the outcomes of these relationships in terms of well-being and job performance.
Rita Pimenta de Devotto   +3 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Examining the mediating and moderating role of psychological capital in the job demands-resources model [PDF]

open access: yes, 2014
Includes bibliographical references.Employee wellbeing has become a major concern for organisations globally, with an increased interest in the prevention of burnout and the maximisation of employee work engagement.
Brouze, Kim Lisa
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Expanding the JD-R Model: is Vocational Fit a resource to consider?

open access: yesStudia Doctoralia, 2018
This study has two main goals. The first would be the extension of the Job Demands-Resources Model with another factor, namely with vocational fit. The other is to examine the relationship between vocational fit, work engagement and burnout, within the same framework. For this purpose, a total of 106 non-randomly selected participants have been invited
openaire   +2 more sources

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

The Role of Career Competencies in the JD-R Model

open access: yesJournal of Vocational Behavior, 2013
This study investigated the role of career competencies as a mediator in the Job Demands - Resources model. Structural equation modeling with data from 305 young employed persons aged 16-30 years showed that career competencies are positively related to job resources and work engagement, but not to job demands and emotional exhaustion.
Akkermans, J.   +3 more
openaire   +2 more sources

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

From Awareness to Action: The Role of AI Awareness in Driving Employee’ Innovation [PDF]

open access: yesالمجلة العربية للإدارة
While artificial intelligence (AI) offers enormous potential for the service sector, it paradoxically creates both opportunity and uncertainty for the workforce.
Adel Zayed   +1 more
doaj   +1 more source

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