Results 81 to 90 of about 27,023,116 (301)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Talent Flow Analytics in Online Professional Network

Data Science and Engineering, 2018
Analyzing job hopping behavior is important for understanding job preference and career progression of working individuals. When analyzed at the workforce population level, job hop analysis helps to gain insights of talent flow among different jobs and ...
Richard J. Oentaryo, Ee-Peng Lim, Xavier Jayaraj Siddarth Ashok, Philips Kokoh Prasetyo, Koon Han Ong, Zi Quan Lau   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Job strain as a risk factor for clinical depression: systematic review and meta-analysis with additional individual participant data

Psychological Medicine, 2017
Background Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed ...
I. Madsen, S. Nyberg, L. Hanson, J. Ferrie, K. Ahola, L. Alfredsson, G. Batty, J. Bjorner, M. Borritz, H. Burr, J. Chastang, R. Graaf, N. Dragano, M. Hamer, M. Jokela, A. Knutsson, M. Koskenvuo, A. Koskinen, C. Leineweber, I. Niedhammer, M. Nielsen, M. Nordin, T. Oksanen, J. Pejtersen, J. Pentti, I. Plaisier, P. Salo, A. Singh‐Manoux, S. Suominen, M. Have, T. Theorell, S. Toppinen-Tanner, J. Vahtera, A. Väänänen, P. Westerholm, H. Westerlund, E. Fransson, K. Heikkilä, K. Heikkilä, M. Virtanen, R. Rugulies, M. Kivimäki   +41 more
semanticscholar   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Workload Analysis to Determine the Optimal Number of Human Resources at Sariraya Co., Ltd

Indonesian Interdisciplinary Journal of Sharia Economics
Sariraya Co., Ltd is a pioneer Indonesian halal food chain based in Aichi, Japan. Sariraya specializes in halal food chains in Japan with several business units such as tempeh factories, restaurants, and halal marts.
Fauzan Nafisa Faryaputra, Kiki Sudiana
doaj   +1 more source

Technostress creators, personality traits, and job burnout: A fuzzy-set configurational analysis

Journal of business research, 2019
Building on the transactional perspective of stress and the complexity theory, we analyzed the effects of personality traits and technostress creators on job burnout by applying the fuzzy-set configurational approach (fsQCA) on a sample of 161 senior ...
Anis Khedhaouria, Alain Cucchi
semanticscholar   +1 more source