Results 81 to 90 of about 23,062,427 (299)

Talent Flow Analytics in Online Professional Network

open access: yesData Science and Engineering, 2018
Analyzing job hopping behavior is important for understanding job preference and career progression of working individuals. When analyzed at the workforce population level, job hop analysis helps to gain insights of talent flow among different jobs and ...
Richard J. Oentaryo   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Workload Analysis to Determine the Optimal Number of Human Resources at Sariraya Co., Ltd

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
Sariraya Co., Ltd is a pioneer Indonesian halal food chain based in Aichi, Japan. Sariraya specializes in halal food chains in Japan with several business units such as tempeh factories, restaurants, and halal marts.
Fauzan Nafisa Faryaputra, Kiki Sudiana
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Job Bros. & Co. Booth.

open access: yes, 1905
A view of a booth displaying products that were produced or distributed by Job Brothers & Co.This collection consists of photographs taken from two Job family albums, reflecting their business ventures, family activities and historical ...
Job, John (William John), b. 1944-
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Job application passport : record the personal information you need to complete most job applications

open access: yes, 2019
Rev. 2/2019.; "OhioMeansJobs.com."; "JFS 33181 (Rev. 2/2019)"--Page 4 of coverOverview -- Personal information -- Education -- Military record -- Work history -- References -- Additional ...
Ohio Department of Job and Family Services
core  

An Empirical Analysis of On-the-Job Search and Job-to-Job Transitions [PDF]

open access: yesWorking paper (Federal Reserve Bank of Philadelphia), 2012
This paper provides a set of simple, yet overlooked, facts regarding on-the-job search and job-to-job transitions using the UK Labour Force Survey (LFS). The LFS is unique in that it asks employed workers whether they search on the job and, if so, why.
openaire   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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