Results 81 to 90 of about 915,850 (329)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Career Calling as the Mediator and Moderator of Job Demands and Job Resources for Job Satisfaction in Health Workers: A Cross-Sectional Study

Frontiers in Psychology, 2022
Job satisfaction of health professionals is a key determinant of the quality of health services and even affects the development of the healthcare system.
Xianhong Huang, Hanlin Chen, Yuan Gao, Jin Wu, Ziling Ni, Xiaohe Wang, Tao Sun   +6 more
doaj   +1 more source

working conditions and individual resources as related factors [PDF]

, 2015
Objectives This study developed and tested a research model that examined the effects of working conditions and individual resources on work–family conflict (WFC) using data collected from physicians working at German clinics.
Bernburg, Monika, Danzer, Gerhard, Groneberg, David A., Klapp, Burghard F., Mache, Stefanie, Vitzthum, Karin   +5 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The job demands-resources model

, 2016
This chapter focuses on one of most influential frameworks, the Job Demands-Resources (JDR) model, which conceptualizes job demands and job resources within the work environment, and how these factors affect health and well-being over time. It reviews the research conducted in relation to the JDR framework, which links job demands and job resources to ...
Taris, Toon, Schaufeli, Wilmar
openaire   +2 more sources

The job demands-resources model of work engagement in South African call centres [PDF]

, 2013
Orientation: A ‘sacrificial human resource strategy’ is practised in call centres, resulting in poor employee occupational health. Consequently, questions are posed in terms of the consequences of call centre work and which salient antecedent variables ...
Billy Boonzaier, Michèle Boonzaier, Yolandi Janse van Rensburg   +2 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

The moderating roles of demands and resources in work engagement and job performance in Chinese service occupations. [PDF]

, 2009
Li, Tsz Wai Gloria.Thesis (M.Phil.)--Chinese University of Hong Kong, 2009.Includes bibliographical references (leaves 34-40).Abstracts in English and Chinese; appendix in Chinese.Abstract --- p.i摘要 --- p.iiiTable of Content --- p.VLists of figures ---

core  

Stress and well-being of University Staff: an investigation using the Demands-Resources-Individual Effects (DRIVE) model and Well-being Process Questionnaire (WPQ). [PDF]

, 2017
Research suggests that university staff have high stress levels but less is known about the well-being of this group. The present study used an adapted version of the Demands-Resources-Individual Effects (DRIVE) model to investigate these topics. It also
Smith, Andrew, Thomas, Kai, Williams, Gary   +2 more
core   +2 more sources