Results 61 to 70 of about 19,029,205 (280)

Motivations, work-family enrichment and job satisfaction: An indirect effects model [PDF]

open access: yes, 2011
Self Determination Theory (SDT) recognises that people may experience their motivations as either coming from within themselves (autonomous) or from outside of themselves (controlled).
Haar, Jarrod, Roche, Maree
core   +1 more source

Impact of work design on psychological work reactions and job performance among technical workers: A longitudinal study in Malaysia [PDF]

open access: yes, 2010
Work design has long been found to affect employee well-being, but scholars have begun to question whether the established theoretical relations regarding work design continue to hold given the enormous changes in the nature of work during the past two ...
Panatik, Siti Aisyah
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Using the Job Demands-Resources Model to Predict Job Satisfaction of Employees in Indonesia [PDF]

open access: yes, 2021
Although the job demands-resources model (JD-R) is getting much attention in the literature, there is limited, if any, empirical research in Indonesia.
Adiarti, Amirah Widia, Dimyati, Dimyati
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Do I want to work from home today? Specific job crafting strategies of public service employees working from home during the COVID-19 pandemic in Germany: a qualitative study

open access: yesFrontiers in Psychology, 2023
BackgroundAfter the outbreak of the COVID-19 pandemic, employees in Europe increasingly worked from home. In the German public sector, many employees experienced working from home for the first time.
Laura Seinsche   +3 more
doaj   +1 more source

Job involvement and valuation of job resources: The mediating effect of satisfaction with job resources [PDF]

open access: yes, 2023
Purpose: This paper has two objectives: the first, to analyse the relationship between job involvement and valuation of job resources; the second, to analyse the mediating effect of satisfaction with job resources on the relationship between job ...
Tobias, Claudia   +6 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Job demands, job resources and safety outcomes: The roles of emotional exhaustion and safety compliance

open access: yes, 2013
The aim of this study was to assess the effectiveness of the job demands-resources (JD-R) model in explaining the relationship of job demands and resources with safety outcomes (i.e., workplace injuries and near-misses).
Yao, Xiang   +4 more
core   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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