Results 41 to 50 of about 333,292 (305)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Towards a new approach to job design research within modern manufacturing : the investigation of employee work orientations. [PDF]
, 1994 In this thesis it is argued that examining the work orientations' of shopfloor employees represents a new and much needed dimension to contemporary job design research.
Parker, S.K., Parker, Sharon
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Ambivalence of Job Autonomy and the Role of Job Design Demands
Scandinavian Journal of Work and Organizational Psychology, 2020 This study aims to explain potentially detrimental effects of job autonomy by introducing the concept of job design demands (JDD); that is, when workers are confronted with jobs that are poorly regulated by the organization, the opportunity to design ...
Jan Dettmers, Franziska Bredehöft
doaj +1 more source
A model for manufacturing cell job redesign [PDF]
, 1997 Cellular manufacturing is widely viewed as an exemplary form of manufacturing organisation for small batch size production. A UK survey states that over 75% of British engineering industry have introduced or are planning to introduce cellular ...
Gassmann, Robert
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Job involvement and valuation of job resources: The mediating effect of satisfaction with job resources [PDF]
, 2023 Purpose: This paper has two objectives: the first, to analyse the relationship between job involvement and valuation of job resources; the second, to analyse the mediating effect of satisfaction with job resources on the relationship between job ...
Tobias, Claudia +6 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source