Results 61 to 70 of about 333,292 (305)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Riesgo ergonómico por movimientos repetitivos del puesto de trabajo del ensamblador de colchones

Revista Cubana de Salud y Trabajo, 2021
Introducción: Los trabajos de fabricación de colchones exponen a los trabajadores a tareas repetitivas que causan la mayoría de las afecciones osteomioarticulares.
Jessica Paola Melendres Villavicencio, Manolo Alexander Córdova Suárez, Vladimir Vega Falcón   +2 more
doaj  

FOSTERING COMMITMENT IN SMES IN BOSNIA AND HERZEGOVINA: FACTORS INFLUENCING AFFECTIVE CONTINUANCE AND NORMATIVE COMMITMENT [PDF]

Business Excellence and Management
Rewards play a crucial role within the framework of exchange theory, serving as a vital component. By acknowledging and rewarding employees, organizations convey appreciation, fostering an environment conducive to teamwork, heightened productivity, and ...
Nereida HADZIAHMETOVIC, Sara POZEGA
doaj   +1 more source

The effects of automation in libraries: the implications for work organisation and job design [PDF]

, 1988
The purpose of this thesis was to investigate how libraries, as organisations, may adapt to the introduction of automation, specifically the use of computing technology. The study focusses on the effects on the organisation of work. The thesis commences
Graham, Margaret Elizabeth
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Preservation, production, and packaging optimization in SMEs: A study on 'Keripik Lumba-Lumba'

OPSI
'Keripik Lumba-Lumba' is a Small and Medium-sized Enterprise (SME) that specializes in the production of cassava chips and banana chips. This SME faces several problems such as raw material shrinkage due to shipping, double work, and different product ...
Ismianti Ismianti, Ibnu Fahrul Rahman, Amorette Garnetta Lasmana, Eka Nur Anisah   +3 more
doaj   +1 more source

Does it take two to tango? Combined effects of relational job crafting and job design on energy and performance [PDF]

Despite an extensive body of research on job crafting, our understanding of how bottom-up job crafting behaviors interact with top-down job design in influencing employee effectiveness remains limited.
Unger, Dana, Bindl, Uta, Doden, Wiebke
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Designing and Explaining the Model of Job Enrichment with the Emphasis on Employee\'s Behavioral Dimension in Social Security Organization

Rāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat, 2022
Background: As a job design technique, job enrichment emphasizes intra-job motivation in job duties and responsibilities to achieve appropriate behavioral outcomes.
Vali Haddadi, Javad Mehrabi, Mohammad Ataee   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source