Results 41 to 50 of about 5,717,728 (239)
Environmental and Occupational Health Practice, 2022 Objectives: This study aims to clarify whether work engagement mediates the relationship between job resources (i.e., supervisor support, coworker support, and job control) and work-to-family positive spillover (WFPS) for home-visiting nursing staff ...
Satoshi Ikeda +7 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The mediating role of optimism and self-efficacy in the relationship between job autonomy and turnover intention [PDF]
PsihologijaThis study sought to find empirical evidence that supports the Job Demands-Resources model’s extension, i.e., the inclusion of personal resources as a mediator between job resources and work-related outcomes in the model.
Mirković Biljana
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Scandinavian Journal of Work, Environment & Health, 2023 OBJECTIVE: Jobs characterized by low job demands and high job resources are associated with better work outcomes, yet it remains unclear whether this is the case for workers with depression.
Patricia Ots +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Organisational climate and its effect on job engagement: exploring the mediating effect of employees level of job satisfaction [PDF]
, 2013 This study examined two under-researched organisational climate facets, integration and family-focused supervisor support, as predictors of employees' job engagement.
Koch, Timothy C
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
, 2018 De JOB-monitor is in 2001 door Jongeren Organisatie Beroepsonderwijs (JOB) opgezet om de tevredenheid van mbo-studenten te meten. Elke twee jaar laat JOB de monitor uitvoeren door onderzoeksbureau ResearchNed.
Wartenbergh-Cras, Drs F.P. (ResearchNed) +1 more
core +1 more source