Results 151 to 160 of about 14,435,632 (168)
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In silico prediction of drug solubility in water-dioxane mixtures using the Jouyban-Acree model.
Die Pharmazie, 2007A numerical method based on the Jouyban-Acree model was presented for prediction of drug solubility in water-dioxane mixtures at various temperatures. The method requires drug solubility in monosolvent systems, i.e. two data points for each temperature of interest. The mean percentage deviation (MPD) of predicted solubilities was calculated to show the
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Journal of Drug Delivery Science and Technology, 2007
A quantitative-structure property relationship (QSPR) was proposed for modeling deviations of solubilities of drugs in water-dioxane mixtures at various temperatures from the predicted solubilities by the Jouyban-Acree model. The QSPR employed the normalized values of the hydration energy, energy of the highest occupied molecular orbital, total energy,
A. Jouyban +3 more
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A quantitative-structure property relationship (QSPR) was proposed for modeling deviations of solubilities of drugs in water-dioxane mixtures at various temperatures from the predicted solubilities by the Jouyban-Acree model. The QSPR employed the normalized values of the hydration energy, energy of the highest occupied molecular orbital, total energy,
A. Jouyban +3 more
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Prediction of drug solubility in water-propylene glycol mixtures using Jouyban-Acree model.
Die Pharmazie, 2007A trained version of the Jouyban-Acree model was presented to predict drug solubility in water-propylene glycol mixtures at various temperatures. The model is able to predict the solubility in various solubility units and requires the experimental solubility of a solute in mono-solvent systems.
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Journal of Solution Chemistry, 2013
The solubility of piroxicam (PIR) in several ethanol + water mixtures was determined at five temperatures from 293.15 to 313.15 K. The thermodynamic functions; Gibbs energy, enthalpy, and entropy of solution and of mixing were obtained from these solubility data and the drug properties of fusion by using the van’t Hoff and Gibbs equations. The greatest
Reinaldo G. Sotomayor +4 more
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The solubility of piroxicam (PIR) in several ethanol + water mixtures was determined at five temperatures from 293.15 to 313.15 K. The thermodynamic functions; Gibbs energy, enthalpy, and entropy of solution and of mixing were obtained from these solubility data and the drug properties of fusion by using the van’t Hoff and Gibbs equations. The greatest
Reinaldo G. Sotomayor +4 more
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AIP Conference Proceedings, 2016
The density of imidazolium-based ionic liquid, 1-ethyl-3-methylimidazolium diethylphosphate with sulfolane were measured at atmospheric pressure. The experiments were performed at T= (293 – 343) K over the complete mole fractions. Physical and thermodynamic properties such as molar volumes, V0, and excess molar volumes, VE for this binary mixtures were
Noraini Abd Ghani +4 more
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The density of imidazolium-based ionic liquid, 1-ethyl-3-methylimidazolium diethylphosphate with sulfolane were measured at atmospheric pressure. The experiments were performed at T= (293 – 343) K over the complete mole fractions. Physical and thermodynamic properties such as molar volumes, V0, and excess molar volumes, VE for this binary mixtures were
Noraini Abd Ghani +4 more
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The Journal of Chemical Thermodynamics, 2019
Abstract In recent years, the number of insoluble drug candidates has increased, with almost 70% of new drug candidates showing poor solubility. Cosolvent was used in this work to improve the solubility of poorly soluble temozolomide. The solubility data of temozolomide in four mixed solvents including (ethyl acetate + methanol), (ethyl acetate ...
Rongrong Li +8 more
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Abstract In recent years, the number of insoluble drug candidates has increased, with almost 70% of new drug candidates showing poor solubility. Cosolvent was used in this work to improve the solubility of poorly soluble temozolomide. The solubility data of temozolomide in four mixed solvents including (ethyl acetate + methanol), (ethyl acetate ...
Rongrong Li +8 more
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Canadian Journal of Chemistry, 2006
The applicability of previously developed quantitative structure-property relationships was extended to predict the solubility of anthracene in nonaqueous binary and ternary solvent mixtures. The accuracy of the proposed methods was evaluated using 81 solubility data sets collected from the literature. The individual and mean percentage deviation (IPD
Abolghasem Jouyban +2 more
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The applicability of previously developed quantitative structure-property relationships was extended to predict the solubility of anthracene in nonaqueous binary and ternary solvent mixtures. The accuracy of the proposed methods was evaluated using 81 solubility data sets collected from the literature. The individual and mean percentage deviation (IPD
Abolghasem Jouyban +2 more
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Analytical Methods, 2010
An extension to the Jouyban-Acree model was proposed to calculate the retention factor of analytes in RPLC with hydro-organic solvent mixtures as mobile phase by using the Abraham solvent coefficients and Abraham solute parameters. The accuracy of the proposed method was checked by computing the mean percentage deviation as a criterion.
Abolghasem Jouyban +3 more
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An extension to the Jouyban-Acree model was proposed to calculate the retention factor of analytes in RPLC with hydro-organic solvent mixtures as mobile phase by using the Abraham solvent coefficients and Abraham solute parameters. The accuracy of the proposed method was checked by computing the mean percentage deviation as a criterion.
Abolghasem Jouyban +3 more
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Fluid Phase Equilibria, 2011
Abstract Solubilities of fluphenazine decanoate (FD) in binary mixtures of propylene glycol + water (PG + W) at 293.2, 298.2, 303.2, 308.2, and 313.2 K are reported. The combination of Jouyban–Acree model and van’t Hoff equation is used to predict the solubility of FD in a given solvent mixture at different temperatures. The thermodynamic properties (
Vahid Panahi-Azar +4 more
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Abstract Solubilities of fluphenazine decanoate (FD) in binary mixtures of propylene glycol + water (PG + W) at 293.2, 298.2, 303.2, 308.2, and 313.2 K are reported. The combination of Jouyban–Acree model and van’t Hoff equation is used to predict the solubility of FD in a given solvent mixture at different temperatures. The thermodynamic properties (
Vahid Panahi-Azar +4 more
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