Results 141 to 150 of about 20,657 (229)

The effect of Ingenol-B on the suppressive capacity of elite suppressor HIV-specific CD8+ T cells.

PLoS ONE, 2017
BackgroundSome latency-reversing agents (LRAs) inhibit HIV-specific CD8+ T cell responses. In a prior study of protein kinase C (PKC) agonists, we found that bryostatin-1 inhibited elite controller/suppressor (ES) CD8+ T cell suppressive activity whereas
Abena K Kwaa, Kennedy Goldsborough, Victoria E Walker-Sperling, Luiz F Pianowski, Lucio Gama, Joel N Blankson   +5 more
doaj   +1 more source

SP048THE BET BROMODOMAIN INHIBITOR JQ1 DIMINISHED RENAL FIBROSIS [PDF]

Nephrology Dialysis Transplantation, 2016
Sandra Rayego-Mateos, José Luis Morgado-Pascual, Beatriz Suarez-Alvarez Suarez-Alvarez, Macarena Orejudo, Raúl R. Rodrigues-Díez, Laura Marquez-Exposito, Jesús Egido, Alberto Ortiz, Carlos Lopez-Larrea, Marta Ruiz-Ortega   +9 more
openaire   +1 more source

BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency.

PLoS Pathogens, 2017
Kaposi's Sarcoma-associated Herpesvirus (KSHV) establishes stable latent infection in B-lymphocytes and pleural effusion lymphomas (PELs). During latency, the viral genome persists as an epigenetically constrained episome with restricted gene expression ...
Horng-Shen Chen, Alessandra De Leo, Zhuo Wang, Andrew Kerekovic, Robert Hills, Paul M Lieberman   +5 more
doaj   +1 more source

BET bromodomain inhibitor (JQ1) and tumor angiogenesis

Oncoscience, 2016
Bid, Hemant Kumar, Kerk, Samuel
openaire   +2 more sources

BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Cell Death and Differentiation, 2022
Diane Moujalled, A. Southon, E. Saleh, Kerstin Brinkmann, F. Ke, Melinda Iliopoulos, R. Cross, Misty R. Jenkins, Duong Nhu, Zilu Wang, Melissa X. Shi, R. Kluck, G. Lessene, S. Grabow, A. Bush, A. Strasser   +15 more
semanticscholar   +1 more source

Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth

Drug Design, Development and Therapy, 2015
Lian Zhang,1 Yingying Tong,1 Xiuli Zhang,1 Minggui Pan,2,3 Siyu Chen1 1Department of Oncology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Oncology and ...
Zhang L, Tong Y, Zhang X, Pan M, Chen S
doaj  

High-intensity interval training alleviates COPD-induced gastrocnemius muscle dysfunction via the BRD4/PGC-1α axis through restoring mitochondrial function and oxidative fiber composition. [PDF]

J Muscle Res Cell Motil
Zhu C, Peng W, Yang L, Zhang W.
europepmc   +1 more source

FLEXTAG: a small and self-renewable protein labeling system for anti-fading multi-color super-resolution imaging. [PDF]

Nat Commun
Zhang H, Yao Y, Wang X, Zheng Y, Zhang S, Tao Y, Yang H, Wang Y, Liu M, Feric M, Zhou R.   +10 more
europepmc   +1 more source

Mechanistic insights and in vivo HIV suppression by the BRD4-targeting small molecule ZL0580. [PDF]

PLoS Pathog
Kumar N, Ma Z, Long F, Bonam SR, Lai HT, Wu SY, Chen H, Hazell NC, Bei J, Liu X, Chen Y, Wei Z, Chiang CM, Zhou J, Hu H.   +14 more
europepmc   +1 more source

MBD3 increased expression by BRD4 and facilitated castration-resistant prostate cancer cell proliferation by inhibiting PTEN. [PDF]

Discov Oncol
Pan L, Shen J, Li Z, Xie G, Chen C, Chen X.   +5 more
europepmc   +1 more source