Results 151 to 160 of about 20,657 (229)

Modulation of Bromo- and Extra-Terminal Domain (BET) Proteins Exerts Neuroprotective Effects in Cell Culture Models of Parkinson's Disease. [PDF]

Biomedicines
Martella N, Pensabene D, Colardo M, Muzzi M, Bisesto E, Varone M, Caretti G, Di Porzio A, Barrella V, Mazzoli A, Di Bartolomeo S, Moreno S, Segatto M.   +12 more
europepmc   +1 more source

MYC-Mediated Functional Manifestation of IDH1 Mutations in Intrahepatic Cholangiocarcinoma Confers Sensitivity to (+)-JQ1. [PDF]

Int J Biol Sci
Wang F, Liu X, Zhang N, Kong R.
europepmc   +1 more source

Bioorthogonal Sonodynamic Plug-and-Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation. [PDF]

Adv Sci (Weinh)
Bao Y, Zhu Y, Wei X, Fang Y, Zhu J, Gao F, Dong G, He S, Sheng C.   +8 more
europepmc   +1 more source

BET Bromodomain Inhibition Reverses CDK4/6 Inhibitor Resistance in Estrogen Receptor-Positive Breast Cancer via Induction of miR-34a-5p. [PDF]

Clin Cancer Res
Liu R, Wang X, Branigan TB, Griffin D, McSweeney C, Hao J, Pantelidou C, Herbert ZT, Jadhav H, Shapiro GI.   +9 more
europepmc   +1 more source

Combinational BET and mTOR inhibition unveils EGR1 as acute myeloid leukemia prognostic biomarker. [PDF]

Sci Rep
Latancia MT, Silva WFD, Bragança-Jardim E, Terra FF, Asprino PF, Pereira WO, Buzatto VC, Galante PA, Inoue LT, Fonseca AR, Kimmemgs TN, Arrais-Rodrigues C, Rocha V, Novis Y, Camara NOS, Lepique AP, Reis LFL, Amano MT.   +17 more
europepmc   +1 more source

Decoding Bromodomain and Extra-Terminal Domain Protein-Mediated Epigenetic Mechanisms in Human Uterine Fibroids. [PDF]

Int J Mol Sci
Yang Q, Vafaei S, Falahati A, Khosh A, Omran MM, Bai T, Bariani MV, Ali M, Boyer TG, Al-Hendy A.   +9 more
europepmc   +1 more source

Bromodomain and extra-terminal proteins in solid tumors: regulators of immune microenvironment and emerging therapeutic targets. [PDF]

Front Immunol
Sharma D, Bushnell GG, Kalman AP, Hutchens CM, Burness ML.   +4 more
europepmc   +1 more source

Fadraciclib, a CDK2/CDK9 inhibitor, shows efficacy in biliary tract cancer and synergistic potential with olaparib and JQ1 based on MCL1 expression. [PDF]

Cell Commun Signal
Kim JM, Nam AR, Oh KS, Bang JH, Jeong Y, Choo SY, Kim HJ, Lee SI, Yoon J, Kim TY, Oh DY.   +10 more
europepmc   +1 more source

Hypoxia-activated paclitaxel prodrugs enable PD-L1 degradation to potentiate cancer chemo-immunotherapy. [PDF]

J Nanobiotechnology
Zhou S, Zhang Q, Han H, Chen G, Wang P, Xue S, Pei Q, Xie Z, Meng X.   +8 more
europepmc   +1 more source

Reactive oxygen species-activated bioorthogonal chemistry in living systems enabled by boronate-caged dihydrotetrazines. [PDF]

Nat Commun
Ming D, Zhang J, Mu B, Peng D, Wang Y, Kong Y, Wang W, Chu L, Wang R, Liu L.   +9 more
europepmc   +1 more source