Results 11 to 20 of about 2,041 (194)
Mediators of Inflammation, 2022 Objective. Identifying new markers of juvenile systemic lupus erythematosus (JSLE) is critical event to predict patient stratification and prognosis. The aim of the present study is to analyze alteration of urinary protein expression and screen potential
Song Zhang +15 more
doaj +2 more sources
Do classic blood biomarkers of JSLE identify active lupus nephritis? Evidence from the UK JSLE Cohort Study. [PDF]
Lupus, 2017 Background Lupus nephritis (LN) affects up to 80% of juvenile-onset systemic lupus erythematosus (JSLE) patients. The value of commonly available biomarkers, such as anti-dsDNA antibodies, complement (C3/C4), ESR and full blood count parameters in the ...
Beresford, MW, Jorgensen, AL, Smith, EMD
core +3 more sources
A novel potential target of IL‐35‐regulated JAK/STAT signaling pathway in lupus nephritis
Clinical and Translational Medicine, 2021 Background In this study, we have investigated the potential regulatory mechanisms of IL‐35 to relieve lupus nephritis (LN) through regulating Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway in mesangial ...
Zhe Cai +9 more
doaj +2 more sources
Molecular Genetics & Genomic Medicine, 2022 Background Genetic variations of neutrophil cytosolic factor 2 (NCF2), a subunit of NADPH oxidase, are usually associated with chronic granulomatous disease, and their relationship with autoimmune disorders through the defective NADPH oxidase function ...
Ivan Y. Bakutenko +8 more
doaj +2 more sources
Factors affecting bone mineral density in children and adolescents with systemic lupus erythematosus [PDF]
Annals of Pediatric Endocrinology & MetabolismPurpose Patients with juvenile-onset systemic lupus erythematosus (JSLE) are at a high risk of entering adulthood with disease-related morbidities like reduced bone mass and osteoporosis.
Su Jin Park +4 more
doaj +2 more sources
Limited sensitivity and specificity of the ACR/EULAR-2019 classification criteria for SLE in JSLE?—observations from the UK JSLE Cohort Study [PDF]
Rheumatology, 2021 Abstract Objectives This study aimed to test the performance of the new ACR and EULAR criteria, that include ANA positivity as entry criterion, in JSLE. Methods Performance of the ACR/EULAR-2019 criteria were compared with Systemic ...
Eve M D Smith +26 more
openaire +5 more sources
COVID19-Related Onset and Relapses of Juvenile Systemic Lupus Erythematosus-Like Disease. [PDF]
J Paediatr Child HealthJournal of Paediatrics and Child Health, Volume 61, Issue 8, Page 1318-1321, August 2025.
Cannata C +3 more
europepmc +2 more sources
European Journal of Investigation in Health, Psychology and Education, 2021 Juvenile systemic lupus erythematosus (JSLE) is diagnosed in children younger than 18 years of age. Depression and anxiety are common, but not well understood in JSLE.
Margarida Figueiredo-Braga +6 more
doaj +1 more source
The role of hsa_circ_0008945 in juvenile-onset systemic lupus erythematosus
BMC Medical Genomics, 2023 Background circular RNAs (circRNAs) play a crucial role in many physiological and pathological processes including juvenile-onset systemic lupus erythematosus (JSLE).
Qifan Wang +6 more
doaj +1 more source
Современная ревматология, 2022 Systemic lupus erythematosus (SLE) with juvenile onset (jSLE) is a complex autoimmune disease involving many organs and systems. The single nucleotide polymorphism rs7574865 of the STAT4 (signal switch and transcription activator 4) gene is associated ...
M. Yu. Krylov +4 more
doaj +1 more source