Results 41 to 50 of about 2,041 (194)

Atopy in children with juvenile systemic lupus erythematosus is associated with severe disease. [PDF]

PLoS ONE, 2017
The influence of co-existing atopy on the prognosis of juvenile systemic lupus erythematosus (JSLE) was assessed in this study. Patients diagnosed with JSLE between October 2005 and April 2016 were enrolled in a prospective study and followed up for 2 ...
Ruru Guo, Yanqing Zhou, Liangjing Lu, Lanfang Cao, Junjia Cao   +4 more
doaj   +1 more source

Use of single photon emission computed tomography and magnetic resonance to evaluate central nervous system involvement in patients with juvenile systemic lupus erythematosus [PDF]

, 2002
The objective of the present study was to identify the single photon emission computed tomography (SPECT) and magnetic resonance (MR) findings in juvenile systemic lupus erythematosus (JSLE) patients with CNS involvement and to try to correlate them with
Alonso, Gilberto, Hilário, Maria Odete Esteves, Lederman, Henrique Manoel, Len, Claudio Arnaldo, Prismich, Glaucia, Quaresma, Marina Rodrigues, Sevillano, Marta Maite, Terreri, Maria Teresa Ramos Ascensão   +7 more
core   +2 more sources

What Have We Learnt About the Treatment of Juvenile-Onset Systemic Lupus Erythematous Since Development of the SHARE Recommendations 2012?

Frontiers in Pediatrics, 2022
IntroductionJuvenile-onset systemic lupus erythematous (JSLE) is a rare multisystem autoimmune disorder. In 2012, the Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) initiative developed recommendations for the diagnosis ...
Kathy L. Gallagher, Pallavi Patel, Michael W. Beresford, Michael W. Beresford, Eve Mary Dorothy Smith, Eve Mary Dorothy Smith   +5 more
doaj   +1 more source

Real world treatment of juvenile-onset systemic lupus erythematosus: Data from the UK JSLE cohort study [PDF]

Clinical Immunology, 2022
In the absence of clinical trials evidence, Juvenile-onset Systemic Lupus Erythematosus (JSLE) treatment plans vary.To explore 'real world' treatment utilising longitudinal UK JSLE Cohort Study data.Data collected between 07/2009-05/2020 was used to explore the choice/sequence of immunomodulating drugs from diagnosis.
Smith EMD, Egbivwie N, Jorgensen AL, Ciurtin C, Al-Abadi E, Armon K, Bailey K, Brennan M, Gardner-Medwin J, Haslam K, Hawley DP, Leahy A, Leone V, Malik G, McLaren Z, Pilkington C, Ramanan AV, Rangaraj S, Ratcliffe A, Riley P, Sen E, Sridhar A, Wilkinson N, Wood F, Beresford MW, Hedrich CM   +25 more
openaire   +4 more sources

CD8+ T-Cells in Juvenile-Onset SLE: From Pathogenesis to Comorbidities

Frontiers in Medicine, 2022
Diagnosis of systemic lupus erythematosus (SLE) in childhood [juvenile-onset (J) SLE], results in a more severe disease phenotype including major organ involvement, increased organ damage, cardiovascular disease risk and mortality compared to adult-onset
Coziana Ciurtin, Coziana Ciurtin, Ines Pineda-Torra, Elizabeth C. Jury, George A. Robinson, George A. Robinson   +5 more
doaj   +1 more source

Role of Chemokine (C–X–C Motif) Ligand 10 (CXCL10) in Renal Diseases

Mediators of Inflammation, Volume 2020, Issue 1, 2020., 2020
Chemokine C–X–C ligand 10 (CXCL10), also known as interferon‐γ‐inducible protein 10 (IP‐10), exerts biological function mainly through binding to its specific receptor, CXCR3. Studies have shown that renal resident mesangial cells, renal tubular epithelial cells, podocytes, endothelial cells, and infiltrating inflammatory cells express CXCL10 and CXCR3
Jie Gao, Lingling Wu, Siyang Wang, Xiangmei Chen, Oleh Andrukhov   +4 more
wiley   +1 more source

Evaluation of magnetic resonance imaging abnormalities in juvenile onset neuropsychiatric systemic lupus erythematosus. [PDF]

, 2016
The aim of this study was to describe the abnormalities identified with conventional MRI in children with neuropsychiatric systemic lupus erythematosus (NPSLE).
Al-Obaidi, M, Brogan, PA, Brown, S, Eleftheriou, D, Martin, N, Moraitis, E, Pilkington, CA, Ramsden, L, Saunders, D   +8 more
core   +1 more source

P166 Possible new role for HCQ in preventing depression in jSLE? [PDF]

Poster presentations, 2020
Background Hydroxychloroquine (HCQ) is a key immunomodulatory treatment in systemic lupus erythematosus (SLE) with pleiotropic effects. Beyond anti-thrombotic, anti-atherosclerotic and anti-diabetic effects, anti-microbial and anti-cancer are possible roles.
Sara Ganhão, Beatriz Silva, Francisca Aguiar, Mariana Rodrigues, Iva Brito, Margarida Figueiredo-Braga   +5 more
openaire   +1 more source

The Comparison of Nailfold Capillaroscopy between Juvenile Systemic Lupus Erythematosus and Healthy Controls: Correlation with Laboratory and Clinical Parameters

International Journal of Vascular Medicine, Volume 2020, Issue 1, 2020., 2020
Background. Nailfold capillaroscopy is a noninvasive technique to recognize peripheral microangiopathy, which is an important feature in systemic lupus erythematosus (SLE). The aims of the present study were to investigate the prevalence of nailfold capillaroscopy (NFC) changes in juvenile systemic lupus erythematosus (JSLE), find out patterns of these
Seyed-Reza Raeeskarami, Navid Namazi, Raheleh Assari, Seyed-Reza Najafizadeh, Zohreh Hassannejad, Vahid Ziaee, Alberto Caggiati   +6 more
wiley   +1 more source

Macrophage activation syndrome (MAS) in juvenile systemic lupus erythematosus (JSLE): an underrecognized complication? [PDF]

Pediatric Rheumatology, 2008
Présentation de l'affiche en libre accès Syndrome d'activation des macrophages (Mas) dans le lupus érythémateux systémique juvénile (JSLE) : une complication méconnue ? A Parodi*1, S Davi1, AB Pringe2, S Magni-Manzoni3, P Miettunen4, B BaderMeunier5, G Espada6, S Ozen7, D Wright8, C Magalhaes9, P Woo10, R Kubchandani11, A Grom12, H Michels13, C ...
Aurora Parodi, Sergio Davì, Pringe Ab, Silvia Magni‐Manzoni, Paivi Miettunen, Brigitte Bader-Meunier, Graciela Espada, Seza Özen, Dowain A. Wright, Cláudia Saad Magalhães, Patricia Woo, Raju Kubchandani, Alexei A. Grom, H. Michels, Carine Wouters, CE Toro Gutierrez, Gary Sterba, Kristen Hayward, Dinara Guseinova, Aryeh Fischer, Elisabetta Cortis, Marina Vivarelli, Angela Pistorio, Nicolino Ruperto, I Sala, Alberto Martini, Angelo Ravelli   +26 more
openaire   +2 more sources