Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts [PDF]
Viruses, 2021 Jumbo phages have attracted much attention by virtue of their extraordinary genome size and unusual aspects of biology. By performing a comparative genomics analysis of 224 jumbo phages, we suggest an objective inclusion criterion based on genome size ...
Lakshminarayan M Iyer +2 more
exaly +5 more sources
Gastrointestinal jumbo phages possess independent synthesis and utilization systems of NAD+ [PDF]
MicrobiomeBackground Jumbo phages, phages with genomes > 200 kbp, contain some unique genes for successful reproduction in their bacterial hosts. Due to complex and massive genomes analogous to those of small-celled bacteria, how jumbo phages complete their life ...
Cunyuan Li +11 more
doaj +6 more sources
The Phage Nucleus and PhuZ Spindle: Defining Features of the Subcellular Organization and Speciation of Nucleus-Forming Jumbo Phages [PDF]
Frontiers in Microbiology, 2021 Bacteriophages and their bacterial hosts are ancient organisms that have been co-evolving for billions of years. Some jumbo phages, those with a genome size larger than 200 kilobases, have recently been discovered to establish complex subcellular ...
Vorrapon Chaikeeratisak +3 more
doaj +6 more sources
Characterization of a novel genus of jumbo phages and their application in wastewater treatment [PDF]
iScience, 2023 Summary: Phages widely exist in numerous environments from wastewater to deep ocean, representing a huge virus diversity, yet remain poorly characterized.
Ming Hu +17 more
doaj +3 more sources
Exploring pangenomic diversity and CRISPR-Cas evasion potential in jumbo phages: a comparative genomics study [PDF]
Microbiology SpectrumJumbo phages are characterized by their remarkably large-sized genome and unique life cycles. Jumbo phages belonging to Chimalliviridae family protect the replicating phage DNA from host immune systems like CRISPR-Cas and restriction-modification system ...
Sharayu Magar +3 more
doaj +3 more sources
Capsid structure of bacteriophage ΦKZ provides insights into assembly and stabilization of jumbo phages [PDF]
Nature CommunicationsJumbo phages are a group of tailed bacteriophages with large genomes and capsids. As a prototype of jumbo phage, ΦKZ infects Pseudomonas aeruginosa, a multi-drug-resistant (MDR) opportunistic pathogen leading to acute or chronic infection in ...
Yashan Yang +12 more
doaj +3 more sources
Comprehensive genome analysis uncovers the diversity of jumbo phages in the pig gut microbiome [PDF]
Frontiers in Veterinary ScienceGut microbiome research has historically focused on bacterial communities. In contrast, the roles of viruses, especially jumbo phages, remain poorly understood.
Chao Wei, Zhe Chen
doaj +3 more sources
Characterization of two related Erwinia myoviruses that are distant relatives of the PhiKZ-like Jumbo phages. [PDF]
PLoS ONE, 2018 Bacteriophages are a major force in the evolution of bacteria due to their sheer abundance as well as their ability to infect and kill their hosts and to transfer genetic material.
Daniel K Arens +14 more
doaj +3 more sources
Replications of Two Closely Related Groups of Jumbo Phages Show Different Level of Dependence on Host-encoded RNA Polymerase [PDF]
Frontiers in Microbiology, 2017 Ralstonia solanacearum phages ΦRP12 and ΦRP31 are jumbo phages isolated in Thailand. Here we show that they exhibit similar virion morphology, genome organization and host range.
Takeru Matsui +9 more
doaj +3 more sources
Characterization and genomic analysis of Sharanji: a jumbo bacteriophage of Escherichia coli [PDF]
Virology JournalBackground Bacteriophages are the most genetically diverse biological entities in nature. Our current understanding of phage biology primarily stems from studies on a limited number of model bacteriophages.
Sharayu Magar +6 more
doaj +3 more sources