Results 21 to 30 of about 5,614 (215)
Virulence, 2023 Mammarenaviruses, a genus of the family Arenaviridae, are capable of infecting mammals and are primarily found in rodent reservoirs worldwide. Mammarenaviruses can be transmitted to humans through contact with infected rodents, and though infection is ...
Brigitte Flannery +2 more
doaj +1 more source
Journal of Medical Virology, Volume 95, Issue 11, November 2023., 2023 Abstract The emerging viruses SARS‐CoV‐2 and arenaviruses cause severe respiratory and hemorrhagic diseases, respectively. The production of infectious particles of both viruses and virus spread in tissues requires cleavage of surface glycoproteins (GPs) by host proprotein convertases (PCs).
Karin Löw +10 more
wiley +1 more source
The Virus–Host Interplay in Junín Mammarenavirus Infection
Viruses, 2022 Junín virus (JUNV) belongs to the Arenaviridae family and is the causative agent of Argentine hemorrhagic fever (AHF), a severe human disease endemic to agricultural areas in Argentina.
Giovanna Lucrecia Gallo +2 more
doaj +1 more source
Family-specific degenerate primer design: a tool to design consensus degenerated oligonucleotides [PDF]
, 2013 Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family-specific degenerate primer design (FAS-DPD) computer ...
Borio, Cristina Silvia +5 more
core +3 more sources
The knowns and unknowns of cardiac autoimmunity in viral myocarditis
Reviews in Medical Virology, Volume 33, Issue 6, November 2023., 2023 Abstract Myocarditis can result from various infectious and non‐infectious causes that can lead to dilated cardiomyopathy (DCM) and heart failure. Among the infectious causes, viruses are commonly suspected. But the challenge is our inability to demonstrate infectious viral particles during clinical presentations, partly because by that point, the ...
Kiruthiga Mone, Jay Reddy
wiley +1 more source
Surface layer proteins in species of the family Lactobacillaceae
Microbial Biotechnology, Volume 16, Issue 6, Page 1232-1249, June 2023., 2023 Manuscript is focus on the prediction of slp genes within the Lactobacillaceae family and interconnection between the two different modular SLP domain organizations of the new reclassified genera. SLP applications are reviewed regarding heterologous display, pathogen exclusion, immunostimulation, and metal binding. Abstract The S‐layer or surface layer
M. Mercedes Palomino +5 more
wiley +1 more source
Targeting of arenavirus RNA synthesis by a carboxamide-derivatized aromatic disulfide with virucidal activity. [PDF]
, 2013 Several arenaviruses can cause severe hemorrhagic fever (HF) in humans, representing a public health threat in endemic areas of Africa and South America.
Damonte, Elsa Beatriz +4 more
core +4 more sources
Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
, 2015 In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet +10 more
core +1 more source
A little less aggregation a little more replication: Viral manipulation of stress granules
WIREs RNA, Volume 14, Issue 1, January/February 2023., 2023 Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley +1 more source
Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections. [PDF]
, 2015 Arenaviruses are one of the largest families of human hemorrhagic fever viruses and are known to infect both mammals and snakes. Arenaviruses package a large (L) and small (S) genome segment in their virions.
Chang, Li-Wen +13 more
core +3 more sources