Results 31 to 40 of about 5,614 (215)

Ribonucleoprotein transport in Negative Strand RNA viruses

open access: yesBiology of the Cell, Volume 115, Issue 1, January 2023., 2023
The genome replication of Negative‐sense, single‐stranded RNA viruses most‐often segregate in membrane‐less environments called inclusion bodies (IBs). These “organelles” usually locate far from the cell surface from where new virions are released. Here, for each viral family, we discuss how the genome progeny is transported from the IBs to reach the ...
Cédric Diot   +2 more
wiley   +1 more source

Standardization of an ELISA test using a recombinant nucleoprotein from the Junin virus as the antigen and serological screening for arenavirus among the population of Nova Xavantina, State of Mato Grosso Padronização de um teste de ELISA utilizando a nucleoproteína recombinante de vírus Junin como antígeno e triagem sorológica para Arenavírus na população de Nova Xavantina, Estado do Mato Grosso

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: Arenavirus hemorrhagic fever is a severe emerging disease. METHODS: Considering that the levels of antibodies against arenavirus in the Brazilian population are completely unknown, we have standardized an ELISA test for detecting IgG ...
Alex Martins Machado   +5 more
doaj   +1 more source

Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]

open access: yes, 2015
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien   +6 more
core   +2 more sources

Interaction of silver nanoparticles with Tacaribe virus [PDF]

open access: yes, 2010
Background Silver nanoparticles possess many unique properties that make them attractive for use in biological applications. Recently they received attention when it was shown that 10 nm silver nanoparticles were bactericidal, which is ...
Janice L Speshock   +4 more
core   +2 more sources

Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies

open access: yesmBio, 2022
Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng   +9 more
doaj   +1 more source

Crystal structure of Junin virus nucleoprotein

open access: yesJournal of General Virology, 2013
Junin virus (JUNV) has been identified as the aetiological agent of Argentine haemorrhagic fever (AHF), which is a serious public health problem with approximately 5 million people at risk. It is treated as a potential bioterrorism agent because of its rapid transmission by aerosols.
Yinjie, Zhang   +8 more
openaire   +2 more sources

Review of Mammarenavirus Biology and Replication

open access: yesFrontiers in Microbiology, 2018
The family Arenaviridae is divided into three genera: Mammarenavirus, Reptarenavirus, and Hartmanivirus. The Mammarenaviruses contain viruses responsible for causing human hemorrhagic fever diseases including New World viruses Junin, Machupo, Guanarito ...
Steven J. Hallam   +3 more
doaj   +1 more source

Structural basis for recognition and regulation of arenavirus polymerase L by Z protein

open access: yesNature Communications, 2021
Junin virus (JUNV) causes Argentine hemorrhagic fever and encodes the large protein (L) of the RNA dependent RNA polymerase (RdRp) and its regulator, the matrix zinc-binding protein (Z).
Huiling Kang   +8 more
doaj   +1 more source

The entry of Junin virus into Vero cells [PDF]

open access: yesArchives of Virology, 1994
The entry mechanism of Junin virus (JV) into Vero cells was studied analyzing the effect of lysosomotropic compounds and acid pH on JV infection. Ammonium chloride, amantadine, chlorpheniramine and procaine inhibited JV production. The action of ammonium chloride was exerted at early times of infection.
Castilla, V.   +3 more
openaire   +2 more sources

Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses

open access: yesNature Communications, 2018
The five known New World hemorrhagic fever arenaviruses use the same entry receptor, but their viral glycoproteins are markedly different. Here, the authors isolate monoclonal antibodies from a Junin virus vaccinated person that cross-neutralize Machupo ...
Lars E. Clark   +12 more
doaj   +1 more source

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