Results 31 to 40 of about 5,614 (215)
Ribonucleoprotein transport in Negative Strand RNA viruses
The genome replication of Negative‐sense, single‐stranded RNA viruses most‐often segregate in membrane‐less environments called inclusion bodies (IBs). These “organelles” usually locate far from the cell surface from where new virions are released. Here, for each viral family, we discuss how the genome progeny is transported from the IBs to reach the ...
Cédric Diot +2 more
wiley +1 more source
INTRODUCTION: Arenavirus hemorrhagic fever is a severe emerging disease. METHODS: Considering that the levels of antibodies against arenavirus in the Brazilian population are completely unknown, we have standardized an ELISA test for detecting IgG ...
Alex Martins Machado +5 more
doaj +1 more source
Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien +6 more
core +2 more sources
Interaction of silver nanoparticles with Tacaribe virus [PDF]
Background Silver nanoparticles possess many unique properties that make them attractive for use in biological applications. Recently they received attention when it was shown that 10 nm silver nanoparticles were bactericidal, which is ...
Janice L Speshock +4 more
core +2 more sources
Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng +9 more
doaj +1 more source
Crystal structure of Junin virus nucleoprotein
Junin virus (JUNV) has been identified as the aetiological agent of Argentine haemorrhagic fever (AHF), which is a serious public health problem with approximately 5 million people at risk. It is treated as a potential bioterrorism agent because of its rapid transmission by aerosols.
Yinjie, Zhang +8 more
openaire +2 more sources
Review of Mammarenavirus Biology and Replication
The family Arenaviridae is divided into three genera: Mammarenavirus, Reptarenavirus, and Hartmanivirus. The Mammarenaviruses contain viruses responsible for causing human hemorrhagic fever diseases including New World viruses Junin, Machupo, Guanarito ...
Steven J. Hallam +3 more
doaj +1 more source
Structural basis for recognition and regulation of arenavirus polymerase L by Z protein
Junin virus (JUNV) causes Argentine hemorrhagic fever and encodes the large protein (L) of the RNA dependent RNA polymerase (RdRp) and its regulator, the matrix zinc-binding protein (Z).
Huiling Kang +8 more
doaj +1 more source
The entry of Junin virus into Vero cells [PDF]
The entry mechanism of Junin virus (JV) into Vero cells was studied analyzing the effect of lysosomotropic compounds and acid pH on JV infection. Ammonium chloride, amantadine, chlorpheniramine and procaine inhibited JV production. The action of ammonium chloride was exerted at early times of infection.
Castilla, V. +3 more
openaire +2 more sources
The five known New World hemorrhagic fever arenaviruses use the same entry receptor, but their viral glycoproteins are markedly different. Here, the authors isolate monoclonal antibodies from a Junin virus vaccinated person that cross-neutralize Machupo ...
Lars E. Clark +12 more
doaj +1 more source

