Results 111 to 120 of about 33,572 (260)
Transport of BMAA into Neurons and Astrocytes by System x\u3csub\u3ec\u3c/sub\u3e- [PDF]
The study of the mechanism of β-N-methylamino-l-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-d-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated.
Albano, Rebecca, Lobner, Doug
core +1 more source
AMPA receptors and seizures mediate hippocampal radial glia-like stem cell proliferation. [PDF]
Neurogenesis is sustained throughout life in the mammalian brain, supporting hippocampus-dependent learning and memory. Its permanent alteration by status epilepticus (SE) is associated with learning and cognitive impairments.
Gray, WP +6 more
core +3 more sources
Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures
The aim of this study was to investigate the role of the synaptic metabotropic zinc receptor mZnR/GPR39 in physiological adaptation to epileptic seizures.
David Gilad +6 more
doaj +1 more source
Ontogeny of kainate-induced gamma oscillations in the rat CA3 hippocampus in vitro [PDF]
International audienceGABAergic inhibition, which is instrumental in the generation of hippocampal gamma oscillations, undergoes significant changes during development.
Cunningham, Mark O. +4 more
core +4 more sources
Dentate granule cells process information from the enthorinal cortex en route to the hippocampus proper. These neurons have a very negative resting membrane potential and are relatively silent in the slice preparation.
Arnaud J Ruiz, Dimitri M Kullmann
doaj +1 more source
Tunable Oscillations in the Purkinje Neuron
In this paper, we study the dynamics of slow oscillations in Purkinje neurons in vitro, and derive a strong association with a forced parametric oscillator model.
A. L. Hodgkin +14 more
core +1 more source
Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system [PDF]
The fine control of molecules mediating communication in the nervous system is key to adjusting neuronal signaling during development and in maintaining the stability of established networks in the face of altered sensory input.
Ales eBalik +3 more
core +2 more sources
Kainate-activated Co2+uptake, a histochemical method that identifies cells bearing Ca2+-permeable AMPA/kainate receptors, labels approximately 15% of murine cortical neurones in cell culture.
Dorothy M. Turetsky +5 more
doaj +1 more source
Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviors [PDF]
Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure threshold of connexin36 knockout (
Cursons, Raymond T. +7 more
core +2 more sources
Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors
Neuropeptide Y (NPY) prominently inhibits epileptic seizures in different animal models. The NPY receptors mediating this effect remain controversial partially due to lack of highly selective agonists and antagonists.
David P.D. Woldbye +7 more
doaj +1 more source

