Results 111 to 120 of about 33,572 (260)

Transport of BMAA into Neurons and Astrocytes by System x\u3csub\u3ec\u3c/sub\u3e- [PDF]

open access: yes, 2018
The study of the mechanism of β-N-methylamino-l-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-d-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated.
Albano, Rebecca, Lobner, Doug
core   +1 more source

AMPA receptors and seizures mediate hippocampal radial glia-like stem cell proliferation. [PDF]

open access: yes, 2018
Neurogenesis is sustained throughout life in the mammalian brain, supporting hippocampus-dependent learning and memory. Its permanent alteration by status epilepticus (SE) is associated with learning and cognitive impairments.
Gray, WP   +6 more
core   +3 more sources

Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures

open access: yesNeurobiology of Disease, 2015
The aim of this study was to investigate the role of the synaptic metabotropic zinc receptor mZnR/GPR39 in physiological adaptation to epileptic seizures.
David Gilad   +6 more
doaj   +1 more source

Ontogeny of kainate-induced gamma oscillations in the rat CA3 hippocampus in vitro [PDF]

open access: yes, 2015
International audienceGABAergic inhibition, which is instrumental in the generation of hippocampal gamma oscillations, undergoes significant changes during development.
Cunningham, Mark O.   +4 more
core   +4 more sources

Ionotropic receptors at hippocampal mossy fibres: roles in axonal excitability, synaptic transmission and plasticity

open access: yesFrontiers in Neural Circuits, 2013
Dentate granule cells process information from the enthorinal cortex en route to the hippocampus proper. These neurons have a very negative resting membrane potential and are relatively silent in the slice preparation.
Arnaud J Ruiz, Dimitri M Kullmann
doaj   +1 more source

Tunable Oscillations in the Purkinje Neuron

open access: yes, 2011
In this paper, we study the dynamics of slow oscillations in Purkinje neurons in vitro, and derive a strong association with a forced parametric oscillator model.
A. L. Hodgkin   +14 more
core   +1 more source

Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system [PDF]

open access: yes, 2013
The fine control of molecules mediating communication in the nervous system is key to adjusting neuronal signaling during development and in maintaining the stability of established networks in the face of altered sensory input.
Ales eBalik   +3 more
core   +2 more sources

Cortical neurones exhibiting kainate-activated Co2+uptake are selectively vulnerable to AMPA/kainate receptor-mediated toxicity

open access: yesNeurobiology of Disease, 1994
Kainate-activated Co2+uptake, a histochemical method that identifies cells bearing Ca2+-permeable AMPA/kainate receptors, labels approximately 15% of murine cortical neurones in cell culture.
Dorothy M. Turetsky   +5 more
doaj   +1 more source

Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviors [PDF]

open access: yes, 2010
Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure threshold of connexin36 knockout (
Cursons, Raymond T.   +7 more
core   +2 more sources

Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

open access: yesNeurobiology of Disease, 2005
Neuropeptide Y (NPY) prominently inhibits epileptic seizures in different animal models. The NPY receptors mediating this effect remain controversial partially due to lack of highly selective agonists and antagonists.
David P.D. Woldbye   +7 more
doaj   +1 more source

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