Results 11 to 20 of about 18,286 (218)
Current Opinion in Pharmacology, 2006 9 páginas, 2 figuras.Glutamate receptors constitute a complex signalling system at most of the excitatory synapses in the brain. Of the known ionotropic glutamate receptors, kainate receptors are ubiquitous in the central nervous system, and a ...
Lerma Gómez, Juan
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Trafficking of Kainate Receptors [PDF]
Membranes, 2014 Ionotropic glutamate receptors (iGluRs) mediate the vast majority of excitatory neurotransmission in the central nervous system of vertebrates. In the protein family of iGluRs, kainate receptors (KARs) comprise the probably least well understood receptor
Steffen Pahl +3 more
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Synaptic plasticity of kainate receptors
Biochemical Society Transactions, 2006 Synaptic plasticity of ionotropic glutamate receptors has been extensively studied with a particular focus on the role played by NMDA (N-methyl-D-aspartate) receptors in the induction of synaptic plasticity and the subsequent movement of AMPA (alpha ...
Mellor, JR
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Cochlear Kainate Receptors [PDF]
Journal of the Association for Research in Otolaryngology, 2012 Synaptic transmission between the cochlear hair cell and its afferent fiber is mediated by glutamate receptors. While kainate receptors are known to be present in the spiral ganglion, little is known of their distribution or functional role. We have detected all five kainate receptor subunits in the mouse cochlea with quantitative RT-PCR and with ...
Marcello, Peppi +2 more
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Kainate Receptors in Health and Disease [PDF]
Neuron, 2013 Our understanding of the molecular properties of kainate receptors and their involvement in synaptic physiology has progressed significantly over the last 30 years. A plethora of studies indicate that kainate receptors are important mediators of the pre- and postsynaptic actions of glutamate, although the mechanisms underlying such effects are still ...
Lerma, Juan, Marques, Joana M.
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Synaptic Targeting of Kainate Receptors [PDF]
Cerebral Cortex, 2014 When native and recombinant kainate receptors (KARs) are compared, there is a mismatch in several of their functional properties. While both generate currents, synaptic responses mediated by KARs have rarely observed in cultured hippocampal neurons.
Palacios-Filardo, Jon +2 more
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Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]
, 2009 NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S. +8 more
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Functional Validation of Heteromeric Kainate Receptor Models. [PDF]
Biophys J, 2017 Kainate receptors require the presence of external ions for gating. Most work thus far has been performed on homomeric GluK2 but, in vivo, kainate receptors are likely heterotetramers. Agonists bind to the ligand-binding domain (LBD) which is arranged as
Paramo T +4 more
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NMDA receptor plasticity in the perirhinal and prefrontal cortices is crucial for the acquisition of long-term object-in-place associative memory [PDF]
, 2008 A key process for recognition memory is the formation of associations between an object and the place in which it was encountered, a process that has been shown to require the perirhinal (PRH) and medial prefrontal (mPFC) cortices.
Barker, Gareth, Warburton, E Clea
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Venom and toxins from Argiope lobata: electrophysiological studies
Біологічні студії, 2020 The purpose of this study was to present experimental data on the action of venom and toxins from Argiope lobata spiders on the glutamate channel-receptor complex.
O. M. Klyuchko
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