Trafficking of Kainate Receptors [PDF]
Membranes, 2014 Ionotropic glutamate receptors (iGluRs) mediate the vast majority of excitatory neurotransmission in the central nervous system of vertebrates. In the protein family of iGluRs, kainate receptors (KARs) comprise the probably least well understood receptor
Steffen Pahl +3 more
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Mitochondrial superoxide production and MnSOD activity following exposure to an agonist and antagonists of ionotropic receptors in rat brain [PDF]
Archives of Biological Sciences, 2005 The involvement of NMDA and AMPA/kainate receptors in the induction of superoxide production in the rat brain was examined after intrahippocampal injection of kainate, a non-NMDA receptor agonist; kainate plus CNQX, a selective AMPA/kainate receptor ...
Radenović Lidija Lj., Selaković Vesna
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Parvalbumin interneurons gate amygdala excitability and response to chronic stress via kainate receptor-driven tonic GABAB receptor-mediated inhibition. [PDF]
Mol PsychiatryRyazantseva M +5 more
europepmc +3 more sources
Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity. [PDF]
Cell Death Dis, 2020 Regoni M +18 more
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Effect of glutamate antagonists on nitric oxide production in rat brain following intrahippocampal injection [PDF]
Archives of Biological Sciences, 2007 Stimulation of glutamate receptors induces neuronal nitric oxide (NO) release, which in turn modulates glutamate transmission. The involvement of ionotropic glutamate NMDA and AMPA/kainate receptors in induction of NO production in the rat brain was ...
Radenović Lidija +3 more
doaj +1 more source
Molecular Physiology of Kainate Receptors [PDF]
Physiological Reviews, 2001 A decade ago, our understanding of the molecular properties of kainate receptors and their involvement in synaptic physiology was essentially null. A plethora of recent studies has altered this situation profoundly such that kainate receptors are now regarded as key players in the modulation of transmitter release, as important mediators of the ...
Juan Lerma +3 more
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Cochlear Kainate Receptors [PDF]
Journal of the Association for Research in Otolaryngology, 2012 Synaptic transmission between the cochlear hair cell and its afferent fiber is mediated by glutamate receptors. While kainate receptors are known to be present in the spiral ganglion, little is known of their distribution or functional role. We have detected all five kainate receptor subunits in the mouse cochlea with quantitative RT-PCR and with ...
Marcello, Peppi +2 more
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Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. [PDF]
PLoS ONE, 2014 Perampanel is an aryl substituted 2-pyridone AMPA receptor antagonist that was recently approved as a treatment for epilepsy. The drug potently inhibits AMPA receptor responses but the mode of block has not been characterized.
Chao-Yin Chen +3 more
doaj +1 more source
Pharmacological analysis of ionotropic glutamate receptor function in neuronal circuits of the zebrafish olfactory bulb. [PDF]
PLoS ONE, 2008 Although synaptic functions of ionotropic glutamate receptors in the olfactory bulb have been studied in vitro, their roles in pattern processing in the intact system remain controversial.
Rico Tabor, Rainer W Friedrich
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Synaptic Targeting of Kainate Receptors [PDF]
Cerebral Cortex, 2014 When native and recombinant kainate receptors (KARs) are compared, there is a mismatch in several of their functional properties. While both generate currents, synaptic responses mediated by KARs have rarely observed in cultured hippocampal neurons.
Palacios-Filardo, Jon +2 more
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