Results 31 to 40 of about 155,737 (137)
Journal of Biotechnology, 2007 A new approach to prepare an acyclic permutant of kalata B1, a cysteine-rich plant cyclopeptide with uterotonic activity, is described. The synthetic codon-optimized cDNA sequence encoding this 29-residue peptide was cloned and fused in-frame to the His ...
Oi Wah Liew, Chum Mok Puah
exaly +5 more sources
Tetrahedron, 2014 Kalata B1 (4) is a prototypical, 29-residue, Möbius cyclotide with a cis prolyl peptide bond in loop 5. Two analogs were synthesized in which Pro24 was substituted by trans-4-hydroxy-l-proline (peptide 5) and cis-4-hydroxy-l-proline (peptide 6).
Carol M Taylor +2 more
exaly +3 more sources
Biochemistry, 1999 Kalata B1 is a member of a new family of polypeptides, isolated from. plants, which have a cystine knot structure embedded within an amide-cyclized backbone.
Daly, N. L. +3 more
core +7 more sources
A comparison of the self-association behavior of the plant cyclotides kalata B1 and kalata B2 via analytical ultracentrifugation [PDF]
Journal of Biological Chemistry, 2003 The recently discovered cyclotides kalata B1 and kalata B2 are miniproteins containing a head-to-tail cyclized backbone and a cystine knot motif, in which disulfide bonds and the connecting backbone segments form a ring that is penetrated by the third ...
Manuela Trabi +7 more
core +6 more sources
Molecular Dynamics Simulations of Drug-Conjugated Cell-Penetrating Peptides [PDF]
Pharmaceuticals, 2023 Cell-penetrating peptides (CPPs) are small peptides capable of translocating through biological membranes carrying various attached cargo into cells and even into the nucleus. They may also participate in transcellular transport.
Márton Ivánczi +3 more
doaj +2 more sources
A Systematic Review of Phytochemistry, Nutritional Composition, and Pharmacologic Application of Species of the Genus Viola in Noncommunicable Diseases (NCDs). [PDF]
Evid Based Complement Alternat Med, 2023 Viola L. is the largest genus of the Violaceae family with more than 500 species across the globe. The present extensive literature survey revealed Viola species to be a group of important nutritional and medicinal plants used for the ethnomedicinal treatment of noncommunicable diseases (NCDs) such as diabetes, asthma, lung diseases, and fatigue.
Batiha GE +8 more
europepmc +2 more sources
Elucidation of the Primary and 3-Dimensional Structure of the Uterotonic Polypeptide Kalata B1
Biochemistry, 1995 The amino acid sequence and structure of a uterotonic polypeptide extracted from the African plant Oldenlandia affinis DC have been determined. The peptide, kalata B1, consists of 29 amino acid residues and is rich in cysteine (6), threonine (5), and ...
Saether, O +11 more
core +7 more sources
Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.
PLoS ONE, 2013 Cyclotides are a diverse and abundant group of ribosomally synthesized plant peptides containing a unique cyclic cystine-knotted topology that confers them with remarkable stability. Kalata B1, a representative member of this family of mini-proteins, has
Carsten Gründemann +8 more
doaj +2 more sources
Journal of Biological Chemistry, 2004 The recently discovered cyclotides kalata B1 and kalata B2 are miniproteins containing a head-to-tail cyclized backbone and a cystine knot motif, in which disulfide bonds and the connecting backbone segments form a ring that is penetrated by the third ...
Amanda Nourse +2 more
exaly +2 more sources
The self‐association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions
Biopolymers, 2013 The cyclotides are a family of small head-to-tail cyclic plant defense proteins. In addition to their cyclic backbone, cyclotides comprise three disulfide bonds in a knotted arrangement, resulting in a highly cross-braced structure that provides ...
K Johan Rosengren +2 more
exaly +2 more sources