Results 21 to 30 of about 4,951 (172)
Gastroenterologìa, 2022 Background. According to evidence, within approximately 8 years, 50 % of patients with chronic pancreatitis (CP) develop endocrine and exocrine insufficiency, which manifests itself as steatorrhea, weight loss, diabetes mellitus (DM), and nutritional ...
L.S. Babinets, I.M. Halabitska
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Brazilian Journal of Medical and Biological Research, 2009 The generation of bradykinin (BK; Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) in blood and kallidin (Lys-BK) in tissues by the action of the kallikrein-kinin system has received little attention in non-mammalian vertebrates.
B.C. Prezoto +5 more
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Reliable measurement of plasma kinin peptides: Importance of preanalytical variables
Research and Practice in Thrombosis and Haemostasis, 2022 Background The kallikrein‐kinin system is involved in many (patho)physiological processes and kinin peptides are considered potential clinical biomarkers.
Tanja Gangnus, Bjoern B. Burckhardt
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Identification of Human Kinin-Forming Enzyme Inhibitors from Medicinal Herbs
Molecules, 2021 The goal of this study was to assess the pharmacological effects of black tea (Camellia sinensis var. assamica) water extract on human kinin-forming enzymes in vitro. Tea is a highly consumed beverage in the world.
Hassan Madkhali +6 more
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The kallikrein–kinin system and oxidative stress [PDF]
Current Opinion in Nephrology & Hypertension, 2012 The Kallikrein-kinin system (KKS) constitutes a complex multi-enzyme cascade that produces several bioactive kinin peptides and their derivatives including bradykinin. In addition to the classical notion of the KKS as a potent vasodilator and a mediator of inflammatory responses, recent studies suggest a link between the KKS and oxidative stress.
Yukako, Kayashima +2 more
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Cardiovascular Activities of of the bradykinin system
The Scientific World Journal, 2008 All the components of the kallikrein-kinin system are located in the cardiac muscle andits deficiency may lead to cardiac dysfunction. In recent years, numerous observationsobtained from clinical and experimental models of diabetes, hypertension ...
Jagdish N. Sharma
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Бюллетень сибирской медицины, 2012 The activity of kallikrein-kinin system of blood and the state of placental circulation at full-term physiological pregnancy have been studied.In 30 pregnant women aged 18—27 at 38th—40th weeks of pregnancy, the activity of kallikrein-kinin system (KKS)
G. T. Kairov +2 more
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Pharmaceuticals, 2010 Terrestrial animals must conserve water and NaCl to survive dry environments. The kidney reabsorbs 95% of the sodium filtered from the glomeruli before sodium reaches the distal connecting tubules. Excess sodium intake requires the renal kallikrein-kinin
Masataka Majima, Makoto Katori
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Viruses, 2021 Background: Coronavirus disease 19 (COVID-19) can develop into a severe respiratory syndrome that results in up to 40% mortality. Acute lung inflammatory edema is a major pathological finding in autopsies explaining O2 diffusion failure and hypoxemia ...
Eli Mansour +19 more
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Mutant plasminogen in hereditary angioedema is bypassing FXII/kallikrein to generate bradykinin
Frontiers in Physiology, 2023 Hereditary angioedema (HAE) is characterized by recurrent localized edema in various organs, which can be potentially fatal. There are different types of hereditary angioedema, which include genetic deficiency of C1 inhibitor (C1-INH) and hereditary ...
Stefan Hintze +12 more
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