Results 71 to 80 of about 38,460 (214)

Imbalance in Renal Vasoactive Enzymes Induced by Mild Hypoxia: Angiotensin-Converting Enzyme Increases While Neutral Endopeptidase Decreases

open access: yesFrontiers in Physiology, 2018
Chronic hypoxia has been postulated as one of the mechanisms involved in salt-sensitive hypertension and chronic kidney disease (CKD). Kidneys have a critical role in the regulation of arterial blood pressure through vasoactive systems, such as the renin-
Carlos P. Vio   +8 more
doaj   +1 more source

Mast Cell Coupling to the Kallikrein–Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease

open access: yesFrontiers in Immunology, 2017
During the course of Chagas disease, infectious forms of Trypanosoma cruzi are occasionally liberated from parasitized heart cells. Studies performed with tissue culture trypomastigotes (TCTs, Dm28c strain) demonstrated that these parasites evoke ...
Clarissa R. Nascimento   +19 more
doaj   +1 more source

Reminiscences of Ervin G Erdös [PDF]

open access: yesScripta Medica, 2019
This article includes personal reminiscence of the great scientist Ervin G Erdös (1922-2019). Dr Erdös was born in Budapest, where he studied medicine. He finished his medical school in Munich, and obtained MD degree in 1952.
Igić Rajko
doaj  

Th2 cytokines increase kallikrein 7 expression and function in atopic dermatitis

open access: yesJournal of Allergy and Clinical Immunology, 2012
Summary Here we report that Th2 cytokines increase kallikrein 7 expression and function in keratinocytes. Our finding describes a link between the Th2 environment and epidermal barrier dysfunction in atopic dermatitis.
S. Morizane   +7 more
semanticscholar   +1 more source

Centralized care model for hereditary angioedema overcomes geographical barriers

open access: yesFrontiers in Immunology
Hereditary angioedema due to C1 inhibitor deficiency (HAE) is a rare inborn error of immunity that presents with episodic swelling. Management is multifaceted and includes on-demand treatment of swelling episodes, short-term prophylaxis to prevent ...
Ashley Holmes   +5 more
doaj   +1 more source

Safety Aspects and Rational Use of Lanadelumab Injections in the Treatment of Hereditary Angioedema (HAE): Clinical Insights

open access: yesDrug, Healthcare and Patient Safety, 2022
Elena Petkova, Vanya Yordanova, Maria Staevska, Anna Valerieva Department of Allergology, Medical University of Sofia, University Hospital “Alexandrovska”, Sofia, BulgariaCorrespondence: Anna Valerieva, Email anna.valerieva@gmail.comAbstract: Hereditary ...
Petkova E   +3 more
doaj  

Isolation and partial characterization of a protease with kallikrein-like activity from the egg-nests of hylesia metabus (crammer 1775) (Lepidoptera: Saturnidae), preliminary communication

open access: yesRevista Científica, 2010
Hylesia metabus is a species of moth, distributed principally in North Eastern Venezuela. Adult females use their abdominal hairs to cover and protect the eggs from predators and parasites.
Ulf Lundberg   +5 more
doaj  

Improving the understanding of plasma kallikrein contribution to arterial thrombus formation using two plant protease inhibitors

open access: yesPlatelets, 2019
The purpose of antithrombotic therapy is the prevention of thrombus formation and/or its extension with a minimum risk of bleeding. The inhibition of a variety of proteolytic processes, particularly those of the coagulation cascade, has been reported as ...
Bruno R Salu   +10 more
doaj   +1 more source

Comparative Analysis of Oral Submucous Fibrosis: A Clinical Assessment and Genetic Biomarkers in Tobacco vs. Non-tobacco Consumers.

open access: yesOnline Journal of Health & Allied Sciences
Objective: To evaluate the oral cavity of tobacco and non-tobacco consumers, focusing on the severity of oral submucous fibrosis (OSF) using clinical diagnostic scales and molecular biomarkers. Design: A comparative cross-sectional study.
Karan Morje   +6 more
doaj  

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