Results 21 to 30 of about 6,082 (161)

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1. [PDF]

open access: yesPLoS ONE, 2012
BackgroundProtein mono-ADP-ribosylation is a reversible post-translational modification that modulates the function of target proteins. The enzymes that catalyze this reaction in mammalian cells are either bacterial pathogenic toxins or endogenous ...
Simone Di Paola   +4 more
doaj   +2 more sources

KPNB1 (karyopherin (importin) beta 1) [PDF]

open access: yes, 2013
Review on KPNB1 (karyopherin (importin) beta 1), with data on DNA, on the protein encoded, and where the gene is ...
Leaner, V   +5 more
core   +2 more sources

Inhibition of NUPR1-Karyopherin β1 Binding Increases Anticancer Drug Sensitivity [PDF]

open access: yes, 2021
Background: Nuclear protein-1 (NUPR1, also known as p8/Com-1) is a transcription factor involved in the regulation of cellular stress responses, including serum starvation and drug stimulation.
박찬희
core   +2 more sources

Karyopherin alpha subtypes and porcine early stage embryo development [PDF]

open access: yes, 2014
Intracellular communication between the nucleus and cytoplasm is critically important for coordinating cellular events during embryogenesis. The karyopherin α/β heterodimer is an intracellular nuclear trafficking system that mediates nuclear import of ...
Li, Yanfang
core   +2 more sources

Negative biomarker based male fertility evaluation: Sperm phenotypes associated with molecular-level anomalies

open access: yesAsian Journal of Andrology, 2015
Biomarker-based sperm analysis elevates the treatment of human infertility and ameliorates reproductive performance in livestock. The negative biomarker-based approach focuses on proteins and ligands unique to defective spermatozoa, regardless of their ...
Peter Sutovsky   +3 more
doaj   +1 more source

The Nuclear Transport Factor Kap121 Is Required for Stability of the Dam1 Complex and Mitotic Kinetochore Bi-orientation

open access: yesCell Reports, 2016
The karyopherin (Kap) family of nuclear transport factors facilitates macromolecular transport through nuclear pore complexes (NPCs). The binding of Kaps to their cargos can also regulate, both temporally and spatially, the interactions of the cargo ...
Lucas V. Cairo, Richard W. Wozniak
doaj   +1 more source

RAM function is dependent on Kapβ2-mediated nuclear entry [PDF]

open access: yes, 2014
Eukaryotic gene expression is dependent on the modification of the first transcribed nucleotide of pre-mRNA by the addition of the 7-methylguanosine cap.
Gonatopoulos-Pournatzis, Thomas   +1 more
core   +1 more source

Supplementary Table from Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer

open access: yes, 2022
Supplementary Table from Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung ...
Trudy G. Oliver (14957133)   +19 more
core   +4 more sources

Effect of transient scrotal hyperthermia on sperm parameters, seminal plasma biochemical markers, and oxidative stress in men

open access: yesAsian Journal of Andrology, 2015
In this experimental prospective study, we aimed to analyze the effect of transient scrotal hyperthermia on the male reproductive organs, from the perspective of sperm parameters, semen plasma biochemical markers, and oxidative stress, to evaluate ...
Meng Rao   +6 more
doaj   +1 more source

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