Results 51 to 60 of about 9,891 (213)

Redox regulation of mammalian sperm capacitation

open access: yesAsian Journal of Andrology, 2015
Capacitation is a series of morphological and metabolic changes necessary for the spermatozoon to achieve fertilizing ability. One of the earlier happenings during mammalian sperm capacitation is the production of reactive oxygen species (ROS) that will ...
Cristian O′Flaherty
doaj   +1 more source

Gene-based genome-wide association studies and meta-analyses of conotruncal heart defects. [PDF]

open access: yes, 2019
Conotruncal heart defects (CTDs) are among the most common and severe groups of congenital heart defects. Despite evidence of an inherited genetic contribution to CTDs, little is known about the specific genes that contribute to the development of CTDs ...
Agopian, AJ   +7 more
core   +2 more sources

Behavioral mechanisms of mammalian sperm guidance

open access: yesAsian Journal of Andrology, 2015
In mammals, sperm guidance in the oviduct appears essential for successful sperm arrival at the oocyte. Hitherto, three different potential sperm guidance mechanisms have been recognized: thermotaxis, rheotaxis, and chemotaxis, each of them using ...
Serafín Pérez Cerezales   +2 more
doaj   +1 more source

A deficit in zinc availability can cause alterations in tubulin thiol redox status in cultured neurons and in the developing fetal rat brain [PDF]

open access: yes, 2011
Zinc (Zn) deficiency during early development can result in multiple brain abnormalities and altered neuronal functions. In rats, a gestational deficit of Zn can affect the fetal brain cytoskeleton, and signaling cascades involved in cellular processes ...
Keen, Carl L.   +4 more
core   +2 more sources

The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition

open access: yesAsian Journal of Andrology, 2015
One of the most common lesions present in the spermatozoa of human infertility patients is an idiopathic failure of sperm-egg recognition. Although this unique cellular interaction can now be readily by-passed by assisted reproductive strategies such as ...
Brett Nixon   +5 more
doaj   +1 more source

Rtp1p Is a Karyopherin-Like Protein Required for RNA Polymerase II Biogenesis [PDF]

open access: yes, 2013
The assembly and nuclear transport of RNA polymerase II (RNA pol II) are processes that require the participation of many auxiliary factors. In a yeast genetic screen, we identified a previously uncharacterized gene, YMR185w (renamed RTP1), which encodes
Ausubel FM   +36 more
core   +1 more source

Microarray Analysis of Gene Expression in Saccharomyces cerevisiae kap108Δ Mutants upon Addition of Oxidative Stress

open access: yesG3: Genes, Genomes, Genetics, 2016
Protein transport between the nucleus and cytoplasm of eukaryotic cells is tightly regulated, providing a mechanism for controlling intracellular localization of proteins, and regulating gene expression. In this study, we have investigated the importance
Kenneth D. Belanger   +4 more
doaj   +1 more source

Developmental regulation of the heat shock response by nuclear transport factor karyopherin-α3 [PDF]

open access: yes, 2001
During early stages of Drosophila development the heat-shock response cannot be induced. It is reasoned that the adverse effects on cell cycle and cell growth brought about by Hsp70 induction must outweigh the beneficial aspects of Hsp70 induction in the
Chen, Tianxin   +3 more
core  

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

A comparative evaluation of semen parameters in pre- and post-Hurricane Katrina human population

open access: yesAsian Journal of Andrology, 2015
A natural disaster leading to accumulation of environmental contaminants may have substantial effects on the male reproductive system. Our aim was to compare and assess semen parameters in a normospermic population residing in the Southern Louisiana, USA
Caner Baran   +2 more
doaj   +1 more source

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