Results 121 to 130 of about 3,763 (189)

Transport of LINE1 retrotransposons into nucleus by karyopherins

Retrotranspozoni LINE1 (ang. long interspersed nuclear element) so avtonomni mobilni DNA elementi, ki predstavljajo 17 % človeškega genoma in so edina aktivna različica transpozicijskih elementov pri človeku.
Nograšek, Tim
core  

Selective transport control on molecular velcro made from intrinsically disordered proteins

, 2014
The selectivity and speed of many biological transport processes transpire from a 'reduction of dimensionality' that confines diffusion to one or two dimensions instead of three. This behaviour remains highly sought after on polymeric surfaces as a means
Sylvia Jeney, Dettmer, Simon L., Pagliara, Stefano, Jeney, Sylvia, Larisa E. Kapinos, Simon L. Dettmer, Ulrich F. Keyser, Schleicher, Kai D., Lim, Roderick Y. H., Kai D. Schleicher, Stefano Pagliara, Dettmer, Simon D., Roderick Y. H. Lim, Kapinos, Larisa E., Keyser, Ulrich F.   +14 more
core   +1 more source

Physiochemical Effects of Nanoparticles on Cell Nuclear Complex Pore Transport: A Coarse-Grained Computational Model

, 2019
Understanding and controlling the interaction between nanoparticles and cell nuclei is critical to the development of the biomedical applications such as gene delivery, cellular imaging, and tumor therapy.
Ramana M. Pidaparti (4395211), Ning Liu (168279), Liuyang Zhang (1563247), Rodney D. Averett (5175065), Xianqiao Wang (1477492), Matthew D. Becton (7463258)   +5 more
core   +1 more source

Identifying a novel region in the Tembusu virus NS5 protein antagonizing type I interferon signaling

Journal of Virology
Numerous species in the genus Flavivirus have been identified to pose serious threats to public health. Most of them have developed evasion strategies to counteract antiviral activity triggered by type I interferon (IFN-I), making prevention and control ...
Ji Zhang, Yunhao Fan, Da An, Mingtian Mao, Zhanbao Guo, Jing Yang, Qiuyue Li, Siming Zhu, Guannan Li, Xin Chen, Zhengkui Zhou, Shuisheng Hou, Youxiang Diao, Yi Tang   +13 more
doaj   +1 more source

Evolutionary and transcriptional analysis of karyopherin beta superfamily proteins

, 2008
In eukaryotes, karyopherin beta superfamily proteins mediate nucleocytoplasmic transport of macromolecules. We investigated the evolutionary and transcriptional patterns of these proteins using bioinformatics approaches. No obvious homologs were found in
Ji, Z. L., Tao, T., 陶涛, Tartakoff, A. M., Quan, Y., Wang, X.   +5 more
core  

Changing expression and subcellular distribution of karyopherins during murine oogenesis

, 2015
Mammalian oocyte growth and development is driven bya strictprogramof gene expression that relieson the timely presence of transcriptional regulators via nuclearpores.By targeting specific cargos for nucleo-cytoplasmic transport, karyopherin (KPN ...
Loveland, Kate L, Mihalas, Bettina P., Western, Patrick S., McLaughlin, Eileen A.; id_orcid, Mihalas, Bettina P, Western, Patrick S, Holt, Janet E, Loveland, Kate L., McLaughlin, Eileen A. (R19932), McLaughlin, Eileen, Holt, Janet E.   +10 more
core   +1 more source

Signals and blockers in karyopherin‐mediated transport (238.1)

The FASEB Journal, 2014
Karyopherinβ (Kap; Importin or Exportin) proteins mediate nucleocytoplasmic transport. Individual Kaps transport unique sets of cargos through recognition of distinct nuclear localization or export signals (NLSs or NESs). Although there are 19 known Kaps in humans, only four classes of signals are known at this time: the short basic classical‐NLS, the ...
openaire   +1 more source

Identification and Characterization of a Novel RanGTP-binding Protein in the Yeast Saccharomyces cerevisiae

, 2003
International audienceThe small Ras-like GTPase Ran plays an essential role in the transport of macromolecules in and out of the nucleus and has been implicated in spindle (1,2 ) and nuclear envelope formation (3,4 ) during mitosis in higher eukaryotes ...
Gerstberger, Thomas, Künzler, Markus, Bischoff, F. Ralf, Legrain, Pierre, Fromont-Racine, Micheline, Braunwarth, Andreas, Hurt, Ed   +6 more
core   +1 more source

Screening of Drosophila importins to identify dTIS11 nuclear import machinery.

, 2013
(A) Human karyopherins and their Drosophila homologs. The identity/similarity of sequence is indicated. (B) Inhibition of Drosophila karyopherin expression by RNA interference. S2 cells were incubated for 4 days in the absence or in the presence of dsRNA
Véronique Kruys (246769), Romuald Soin (444009), Corinne Wauquier (444008), Laure Twyffels (444007), Christine Decaestecker (214320), Cyril Gueydan (246766)   +5 more
core   +1 more source

Biochemical Analysis of the Protein-Protein Interactions Involved in Karyopherin-Mediated Transport Across the Nuclear Pore Complex

, 2009
Nucleocytoplasmic transport occurs through the nuclear pore complex (NPC), which in yeast is a highly symmetric ~50 MDa complex consisting of approximately 30 different proteins.
Tetenbaum-Novatt, Jaclyn
core   +1 more source