Results 131 to 140 of about 6,766 (259)
ABSTRACT Background Abnormal protein localization due to disrupted nucleoplasmic transport is common in tumor cells, but its mechanisms are not well understood. Nuclear pore complexes and nuclear transporter proteins are crucial for protein transport between the nucleus and cytoplasm.
Yanming Hu +9 more
wiley +1 more source
Pleomorphic adenoma gene 1 mediates the role of Karyopherin alpha 2 and has prognostic significance in hepatocellular carcinoma [PDF]
Zhe-yuan Hu +4 more
openalex +2 more sources
Yeast karyopherin Kap95 is required for cell cycle progression at Start
Background The control of the subcellular localization of cell cycle regulators has emerged as a crucial mechanism in cell division regulation. The active transport of proteins between the nucleus and the cytoplasm is mediated by the transport receptors ...
Igual Juan, Taberner Francisco
doaj +1 more source
Cell Host-Microbe Interactions: Turning Pathogen Mechanisms Into Cell's Advantages [PDF]
Host-Pathogen Interaction is a very vast field of biological sciences, indeed every year many un- known pathogens are uncovered leading to an exponential growth of this field.
Avanzi, Simone <1982>
core +1 more source
Abstract The easiest and often most useful way to work with experimentally determined or computationally predicted structures of biomolecules is by viewing their three‐dimensional (3D) shapes using a molecular visualization tool. Mol* was collaboratively developed by RCSB Protein Data Bank (RCSB PDB, RCSB.org) and Protein Data Bank in Europe (PDBe ...
Sebastian Bittrich +14 more
wiley +1 more source
The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly. [PDF]
It is unknown whether the mammalian cell cycle could impact the assembly of viruses maturing in the nucleus. We addressed this question using MVM, a reference member of the icosahedral ssDNA nuclear parvoviruses, which requires cell proliferation to ...
Almendral, JM +5 more
core +7 more sources
Background Members of the karyopherin superfamily serve as nuclear transport receptors/adaptor proteins and provide exchange of macromolecules between the nucleo- and cytoplasm.
Elisabeth Drucker +12 more
doaj +1 more source
Background The Mitotic Exit Network (MEN) proteins – including the protein kinase Cdc15 and the protein phosphatase Cdc14 – are essential for exit from mitosis in Saccharomyces cerevisiae.
Deshaies Raymond J, Shou Wenying
doaj +1 more source
The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation [PDF]
Histone chaperones physically interact with histones to direct proper assembly and disassembly of nucleosomes regulating diverse nuclear processes such as DNA replication, promoter remodeling, transcription elongation, DNA damage, and histone variant ...
Bowman, A. +6 more
core +4 more sources

