Results 131 to 140 of about 6,766 (259)

KPNA5 Suppresses Malignant Progression of Ovarian Cancer Through Importing the PTPN4 Into the Nucleus

open access: yesCancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Background Abnormal protein localization due to disrupted nucleoplasmic transport is common in tumor cells, but its mechanisms are not well understood. Nuclear pore complexes and nuclear transporter proteins are crucial for protein transport between the nucleus and cytoplasm.
Yanming Hu   +9 more
wiley   +1 more source

Yeast karyopherin Kap95 is required for cell cycle progression at Start

open access: yesBMC Cell Biology, 2010
Background The control of the subcellular localization of cell cycle regulators has emerged as a crucial mechanism in cell division regulation. The active transport of proteins between the nucleus and the cytoplasm is mediated by the transport receptors ...
Igual Juan, Taberner Francisco
doaj   +1 more source

Cell Host-Microbe Interactions: Turning Pathogen Mechanisms Into Cell's Advantages [PDF]

open access: yes, 2013
Host-Pathogen Interaction is a very vast field of biological sciences, indeed every year many un- known pathogens are uncovered leading to an exponential growth of this field.
Avanzi, Simone <1982>
core   +1 more source

Visualizing and analyzing 3D biomolecular structures using Mol* at RCSB.org: Influenza A H5N1 virus proteome case study

open access: yesProtein Science, Volume 34, Issue 4, April 2025.
Abstract The easiest and often most useful way to work with experimentally determined or computationally predicted structures of biomolecules is by viewing their three‐dimensional (3D) shapes using a molecular visualization tool. Mol* was collaboratively developed by RCSB Protein Data Bank (RCSB PDB, RCSB.org) and Protein Data Bank in Europe (PDBe ...
Sebastian Bittrich   +14 more
wiley   +1 more source

The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly. [PDF]

open access: yes, 2015
It is unknown whether the mammalian cell cycle could impact the assembly of viruses maturing in the nucleus. We addressed this question using MVM, a reference member of the icosahedral ssDNA nuclear parvoviruses, which requires cell proliferation to ...
Almendral, JM   +5 more
core   +7 more sources

Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer

open access: yesCell Communication and Signaling, 2019
Background Members of the karyopherin superfamily serve as nuclear transport receptors/adaptor proteins and provide exchange of macromolecules between the nucleo- and cytoplasm.
Elisabeth Drucker   +12 more
doaj   +1 more source

Multiple telophase arrest bypassed (tab) mutants alleviate the essential requirement for Cdc15 in exit from mitosis in S. cerevisiae

open access: yesBMC Genetics, 2002
Background The Mitotic Exit Network (MEN) proteins – including the protein kinase Cdc15 and the protein phosphatase Cdc14 – are essential for exit from mitosis in Saccharomyces cerevisiae.
Deshaies Raymond J, Shou Wenying
doaj   +1 more source

The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation [PDF]

open access: yes, 2011
Histone chaperones physically interact with histones to direct proper assembly and disassembly of nucleosomes regulating diverse nuclear processes such as DNA replication, promoter remodeling, transcription elongation, DNA damage, and histone variant ...
Bowman, A.   +6 more
core   +4 more sources

Supplementary Table from Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer

open access: gold, 2023
Demetra P. Kelenis   +9 more
openalex   +2 more sources

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