Results 61 to 70 of about 1,046 (117)

Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium Analysis

Earth's Future, Volume 13, Issue 2, February 2025.
Abstract Selenium is an essential micronutrient, yet its deficiency poses severe health risks, including Kashin‐Beck disease, a debilitating disorder endemic to selenium‐deficient regions like Tibet. Despite the known risks, the extent and drivers of selenium deficiency in Tibetan populations remain poorly characterized.
Yi Yang, Ru Zhang, Yangzong Deji, You Li, Yonghua Li   +4 more
wiley   +1 more source

Evaluation of Soil Samples Preparation Techniques for Detecting Selenium by Using Atomic Fluorescence Spectroscopy‐Based Detection

Journal of Analytical Methods in Chemistry, Volume 2025, Issue 1, 2025.
Selenium (Se) can cause poisoning in the human body, including dry, brittle, and easy‐to‐fall‐off hair, white spots and longitudinal lines of nails, skin damage, nervous system abnormalities, and even death. In order to optimize the experimental process for the sensitive detection of Se in samples by atomic fluorescence spectrometry (AFS), an excellent
Lin Zhu, Zheng-he Hu, Xiu-long Chen, Surat Hongsibsong, Tulika Banerjee   +4 more
wiley   +1 more source

Genetic variants in the ITPR2 gene are associated with Kashin‐Beck Disease in Tibetan

Molecular Genetics & Genomic Medicine, 2019
Background Kashin‐Beck Disease (KBD) is a chronic, endemic osteoarthropathy. Inositol 1,4,5‐triphosphate receptor type 2 (ITPR2) gene is involved in chondrocytes.
Xue He, Mei Bai, Ming Liu, Li Wang, Yongjun He, Hao Rong, Dongya Yuan, Tianbo Jin   +7 more
doaj   +1 more source

A Se Nanoparticle/MgFe‐LDH Composite Nanosheet as a Multifunctional Platform for Osteosarcoma Eradication, Antibacterial and Bone Reconstruction

Advanced Science, Volume 11, Issue 33, September 4, 2024.
Selenium nanoparticle‐decorated MgFe‐LDH nanosheets are loaded on a bioactive glass scaffold to develop a postoperative “one‐stop‐shop” therapeutic platform for osteosarcoma. Abstract Despite advances in treating osteosarcoma, postoperative tumor recurrence, periprosthetic infection, and critical bone defects remain critical concerns.
Yixin Bian, Kexin Zhao, Tingting Hu, Chaoliang Tan, Ruizheng Liang, Xisheng Weng   +5 more
wiley   +1 more source

Theranostic scope of monometallic selenium and titanium dioxide nanoparticles in biomedicine: A review

Health Care Science, Volume 3, Issue 4, Page 215-231, August 2024.
The nanoparticles (NPs) of metals and metal oxides constitute significant components of technology in terms of monometallic NPs (MNPs). Throughout the last 10 years, the most fascinating and in‐depth uses of NPs have been found in the biomedical field, which has demonstrated the therapeutic potential of these particles. Significant strides were made in
Shwetha B. Nagarajan, Anuradha Jayaraman, Sanjeevi Ramakrishnan   +2 more
wiley   +1 more source

The levels of urine CTX-II, C2C, and PYD in children patients with Kashin-Beck disease in Qinghai Province of China

Journal of Orthopaedic Surgery and Research, 2019
Background Kashin-Beck disease (KBD) is an endemic and chronic osteoarthropathy. At present, the diagnosis of KBD mainly depends on the X-ray examination and which could not reflect early damage of cartilage sensitively.
Wanying Wang, Lihua Wang, Qing Deng, Yun Cai, Xianhao Wu, Liyan Sun   +5 more
doaj   +1 more source

The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies

Experimental and Molecular Medicine, 2020
Joint health: the rare micronutrient selenium may be crucial Selenium, a micronutrient found in brazil nuts, shiitake mushrooms, and most meats, may aid in treating joint diseases, including the most common form of arthritis, osteoarthritis (OA).
Donghyun Kang, Jeeyeon Lee, Cuiyan Wu, Xiong Guo, Byeong Jae Lee, Jang-Soo Chun, Jin-Hong Kim   +6 more
doaj   +1 more source

Potential involvement of connective tissue growth factor in chondrocytes apoptosis of Kashin-Beck disease

Ecotoxicology and Environmental Safety
Background: Kashin-Beck disease (KBD) is an endemic osteoarthropathy characterized by excessive chondrocytes apoptosis. T-2 toxin exposure has been proved to be its etiology. Connective tissue growth factor (CTGF) exerts a profound influence on cartilage
Xuena Yang, Huan Liu, Shiqiang Cheng, Chuyu Pan, Qingqing Cai, Xiaoge Chu, Sirong Shi, Wenming Wei, Dan He, Bolun Cheng, Yan Wen, Yumeng Jia, Alexey A. Tinkov, Anatoly V. Skalny, Feng Zhang   +14 more
doaj   +1 more source

WISP1 Is Involved in the Pathogenesis of Kashin-Beck Disease via the Autophagy Pathway. [PDF]

Int J Mol Sci, 2023
Li P, Cheng B, Yao Y, Yu W, Liu L, Cheng S, Zhang L, Ma M, Qi X, Liang C, Chu X, Ye J, Sun S, Jia Y, Guo X, Wen Y, Zhang F.   +16 more
europepmc   +1 more source

A Metabolomics Study of Feces Revealed That a Disturbance of Selenium-Centered Metabolic Bioprocess Was Involved in Kashin-Beck Disease, an Osteoarthropathy Endemic to China. [PDF]

Nutrients, 2023
Wen Y, Wang B, Shi P, Chu X, Shi S, Yao Y, Zhang L, Zhang F.   +7 more
europepmc   +1 more source