Results 51 to 60 of about 10,432,347 (134)

Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy kashin-beck disease

BMC Musculoskeletal Disorders, 2012
Background Kashin-Beck Disease (KBD) is an endemic osteochondropathy. Mycotoxins are believed to play an important role in the pathogenesis of KBD. Because the molecular mechanism of mycotoxin-induced cartilage lesions remains unclear, there is not ...
Zhang Feng, Guo Xiong, Wang Weizhuo, Wu Shixun, Ma Weijuan, Yan Hua   +5 more
doaj   +1 more source

Osteoarthritis Deformans Endemica: Etiology, Diagnosis, Treatment, Prevention

Bolʹ, Sustavy, Pozvonočnik, 2012
The paper deals with generalization of historical, epidemiological, etiologic, diagnostic, preventive and therapeutic data of osteoarthritis deformans endemica (Kashin — Beck disease). Taking into account the growing trend of deterioration of the current
T.V. Frolova, О.V. Okhapkina, Yu.V. Sorokolat, Ye.G. Koleushko   +3 more
doaj   +1 more source

Sex differences in joint pain, limb function and quality of life among patients with Kashin-Beck disease in Northwest China. [PDF]

BMC Musculoskelet Disord
Kashin–Beck disease (KBD) remains a significant public health challenge in northwestern China, where chronic joint pain and functional limitations severely compromise quality of life (QoL).
Wang D, Younus MI, Fang H, Mu H, Xu C, Guo X, Zhang YP.   +6 more
europepmc   +2 more sources

Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis

Arthritis Research & Therapy, 2018
Background Kashin-Beck disease (KBD) is an endemic osteochondropathy of unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar clinical manifestations and pathological changes to articular cartilage with KBD ...
Yan Wen, Ping Li, Jingcan Hao, Chen Duan, Jing Han, Awen He, Yanan Du, Li Liu, Xiao Liang, Feng Zhang, Xiong Guo   +10 more
doaj   +1 more source

Spatial distribution and determinants of health loss from Kashin-Beck disease in Bin County, Shaanxi Province, China

BMC Public Health, 2021
Background Kashin-Beck disease (KBD) is one of the major endemic diseases in China, which severely impacts the physical health and life quality of people.
Jing Wang, Xiaoya Wang, Hairong Li, Linsheng Yang, Yingchun Li, Chang Kong   +5 more
doaj   +1 more source

Cytotoxic Properties of HT-2 Toxin in Human Chondrocytes: Could T₃ Inhibit Toxicity of HT-2?

Toxins, 2019
Thyroid hormone triiodothyronine (T3) plays an important role in coordinated endochondral ossification and hypertrophic differentiation of the growth plate, while aberrant thyroid hormone function appears to be related to skeletal malformations ...
Feng’e Zhang, Mikko Juhani Lammi, Wanzhen Shao, Pan Zhang, Yanan Zhang, Haiyan Wei, Xiong Guo   +6 more
doaj   +1 more source

Whole-exome sequencing for the identification of susceptibility genes of Kashin-Beck disease.

PLoS ONE, 2014
ObjectiveTo identify and investigate the susceptibility genes of Kashin-Beck disease (KBD) in Chinese population.MethodsWhole-exome capturing and sequencing technology was used for the detection of genetic variations in 19 individuals from six families ...
Zhenxing Yang, Yu Xu, Hongrong Luo, Xiaohong Ma, Qiang Wang, Yingcheng Wang, Wei Deng, Tao Jiang, Guangqing Sun, Tingting He, Jingchu Hu, Yingrui Li, Jun Wang, Tao Li, Xun Hu   +14 more
doaj   +1 more source

Evaluation of Storage Conditions and Pre‐Treatment Methods to Mitigate Aflatoxin Contamination in Commonly Used Chinese Herbal Medicines

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
High temperature and humidity significantly promote aflatoxin contamination in herbal medicines. This research demonstrates that drying, vacuum packaging, and sulfur fumigation are effective strategies to minimize contamination and extend shelf life, whereas UV exposure proves ineffective for decontamination.
Tung Leong Fong, Tingyuan Xing, Yau‐Tuen Chan, Zixin Feng, Guoyi Tang, Yibin Feng, Cheng Zhang, Ning Wang   +7 more
wiley   +1 more source

Chemical composition of natural waters from the Urov endemic area

Desalination and Water Treatment
Owing to the importance of drinking water in human nutrition, in this study, we performed a comparative analysis of the chemical composition of drinking water from settlements endemic to Kashin–Beck disease and from territories that are not endemic to ...
Vadim Ermakov, Vladimir Safonov, Valentina Danilova, Uliana Gulyaeva, Sergey Tyutikov   +4 more
doaj   +1 more source

Unlocking the Nutritional Potential of Gamma Amino Butyric Acid (GABA) Rice: Towards a Sustainable Approach to Metabolic Disorder Remedies

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
This study addresses the critical issue of nutrient deficiencies associated with the widespread consumption of conventional milled rice, which often lacks essential vitamins and minerals due to the removal of the bran layer during processing. It demonstrated that controlled germination of paddy rice, followed by parboiling, substantially increases the ...
Uloma E. Onyeka, Ekpeno Sunday Ukpong, Chinedu B. Azudialu, Sali A. Ndindeng, Kalimuthu Senthilkumar, Christian O. Dimkpa   +5 more
wiley   +1 more source