Results 31 to 40 of about 10,432,347 (134)

Hydrochemical characteristics of surface waters and their relationships to the Kashin–Beck Disease in Longzi County, Tibet [PDF]

Scientific Reports, 2022
Although previous studies have been reported between the Kashin–Beck Disease (KBD) epidemic and the hydrochemical characteristics of surface waters, the etiology of the disease remains unclear.
Xinjie Zha, Yuan Tian, Jianyu Xiao, Chengqun Yu   +3 more
doaj   +2 more sources

Investigation of selenium nutritional status and dietary pattern among children in Kashin-Beck disease endemic areas in Shaanxi Province, China using duplicate portion sampling method

Environment International, 2022
Background and objectives: Selenium deficiency is a primary risk factor of Kashin-Beck disease (KBD). This study aimed to investigate whether children in endemic areas could maintain sufficient selenium intake after termination of selenium supplement ...
Yujie Ning, Minhan Hu, Sijie Chen, Feiyu Zhang, Xiaodong Yang, Qingping Zhang, Yi Gong, Ruitian Huang, Yanli Liu, Feihong Chen, Leilei Pei, Xiong Guo, Lianke Kang, Xinyi Wang, Yan Zhang, Xi Wang   +15 more
doaj   +2 more sources

Correction: A study on atypical Kashin–Beck disease: an endemic ankle arthritis [PDF]

Journal of Orthopaedic Surgery and Research, 2023
Fang Qi, Si-Lu Cui, Bing Zhang, Hao-Nan Li, Jun Yu   +4 more
doaj   +2 more sources

A blood-based four-gene diagnostic signature for Kashin–Beck disease revealed by multi-cohort transcriptomic analysis and machine learning [PDF]

Frontiers in Immunology
BackgroundKashin–Beck disease (KBD) is an endemic osteoarthropathy characterized by growth retardation and progressive joint degeneration. However, its systemic molecular features in peripheral blood remain incompletely understood.MethodsPeripheral blood
Minghui Guo, Minghui Guo, Kunkun Yang, Kunkun Yang, Shizhang Liu, Shizhang Liu, Zhengming Sun, Zhengming Sun, Xueyuan Wu, Xueyuan Wu, Xinpei Li, Xinpei Li, Yuchao Wang, Yuchao Wang, Xinke Zhu, Ming Ling, Ming Ling   +16 more
doaj   +2 more sources

Comparison of the responsiveness of the WOMAC and the 12-item WHODAS 2.0 in patients with Kashin–Beck disease [PDF]

BMC Musculoskeletal Disorders, 2020
Background Several questionnaires have been used to assess the health status of patients with Kashin-Beck disease (KBD) in clinical trials, but the evidence regarding the responsiveness of these instruments in KBD patients is limited.
Lei Yang, Dimiao Wang, Xiuxia Li, Hangjing Yuan, Hua Fang, Xiong Guo   +5 more
doaj   +2 more sources

The molecular mechanism study of COMP involved in the articular cartilage damage of Kashin-Beck disease [PDF]

Bone & Joint Research, 2020
Aims: Kashin-Beck disease (KBD) is a kind of chronic osteochondropathy, thought to be caused by environmental risk factors such as T-2 toxin. However, the exact aetiology of KBD remains unclear.
Mei Ma, Xiao Liang, Xi Wang, Lu Zhang, Shiqiang Cheng, Xiong Guo, Feng Zhang, Yan Wen   +7 more
doaj   +2 more sources

Long-term outcomes of arthroscopic debridement of the knee in adults with Kashin–Beck disease: an 18-year follow-up [PDF]

Journal of International Medical Research, 2021
Objective Kashin–Beck disease (KBD) is an endemic degenerative joint disease with a high disability rate. We retrospectively evaluated the 18-year clinical follow-up outcomes of adult patients with KBD who underwent arthroscopic debridement for knee ...
Zhan-Kui Jin, Cui-Xiang Xu, Xiang-Hui Dong, Ming Ling, Ming Chen, Zhi Yi, Shi-Zhang Liu, Xue-Yuan Wu, Zheng-Ming Sun, Yan-Hai Chang   +9 more
doaj   +2 more sources

Association of SOX6 gene polymorphisms with Kashin-Beck disease risk in the Chinese Han population [PDF]

Open Medicine
Kashin-Beck disease (KBD) is an endemic osteochondropathy. A specific gene called SRY-box transcription factor 6 (SOX6) is important for forming cartilage. This study aims to explore the potential correlation between SOX6 single nucleotide polymorphisms (
He Na, Hong Aiwen, Zhao Kun, Zhang Zhefan, Wang Shengli, Jia Yaofei   +5 more
doaj   +2 more sources

Potential involvement of connective tissue growth factor in chondrocytes apoptosis of Kashin-Beck disease

Ecotoxicology and Environmental Safety
Background: Kashin-Beck disease (KBD) is an endemic osteoarthropathy characterized by excessive chondrocytes apoptosis. T-2 toxin exposure has been proved to be its etiology. Connective tissue growth factor (CTGF) exerts a profound influence on cartilage
Xuena Yang, Huan Liu, Shiqiang Cheng, Chuyu Pan, Qingqing Cai, Xiaoge Chu, Sirong Shi, Wenming Wei, Dan He, Bolun Cheng, Yan Wen, Yumeng Jia, Alexey A. Tinkov, Anatoly V. Skalny, Feng Zhang   +14 more
doaj   +2 more sources

County-Level Hotspot Identification and Spatial Regression Analysis of Health Loss from Kashin-Beck Disease - China, 2019 and 2023. [PDF]

China CDC Wkly
Introduction We analyzed the spatial distribution of years lived with disability (YLDs) among patients with Kashin-Beck disease (KBD) at the county level across the country, identified hotspot regions and the primary areas of disease burden.
Liu Y, Qi F, Du H, Li H, Zheng S, Yu Q, Dong H, Wang C, Li J, Zhao Y, Li J, Yu J.   +11 more
europepmc   +2 more sources