Effects of selenium and iodine on Kashin-Beck disease: an updated review [PDF]
Frontiers in NutritionKashin-Beck disease (KBD) is an endochondral osteogenesis disorder characterised by epiphysis damage and secondary deformable arthropathy induced by multiple external factors, among which selenium (Se) and iodine deficiency are important influencing ...
Lin Liu, Pan Luo, Pengfei Wen, Peng Xu
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Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China [PDF]
Arthritis Research & Therapy, 2022 Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning +15 more
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The Status of Selenium and Zinc in the Urine of Children From Endemic Areas of Kashin-Beck Disease Over Three Consecutive Years [PDF]
Frontiers in Nutrition, 2022 Selenium deficiency is one of the main risk factors for Kashin-Beck disease (KBD). This study aimed to detect the status of selenium and zinc in the urine of children from endemic areas of KBD over three consecutive years and to evaluate whether selenium
Xin Kang +15 more
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Identification of energy metabolism and m6A-related gene clusters in Kashin-Beck disease based on bioinformatics analysis [PDF]
BMC Musculoskeletal DisordersKashin-Beck disease (KBD) is a chronic and debilitating osteoarthropathy predominantly affecting populations in certain endemic regions. Despite extensive research, the underlying mechanisms of KBD remain poorly understood.
Ao Zhou +6 more
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Correction: A study on atypical Kashin–Beck disease: an endemic ankle arthritis [PDF]
Journal of Orthopaedic Surgery and Research, 2023 Fang Qi +4 more
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Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease [PDF]
Frontiers in Cell and Developmental BiologyObjectiveKashin-Beck disease (KBD) is a nutrition-related osteoarthropathy characterized by excessive apoptosis and matrix destruction. Micronutrient selenium (Se) deficiency is recognized as a major environmental risk factor.
Di Zhang +5 more
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Hydrochemical characteristics of surface waters and their relationships to the Kashin–Beck Disease in Longzi County, Tibet [PDF]
Scientific Reports, 2022 Although previous studies have been reported between the Kashin–Beck Disease (KBD) epidemic and the hydrochemical characteristics of surface waters, the etiology of the disease remains unclear.
Xinjie Zha +3 more
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Association of SOX6 gene polymorphisms with Kashin-Beck disease risk in the Chinese Han population [PDF]
Open MedicineKashin-Beck disease (KBD) is an endemic osteochondropathy. A specific gene called SRY-box transcription factor 6 (SOX6) is important for forming cartilage. This study aims to explore the potential correlation between SOX6 single nucleotide polymorphisms (
He Na +5 more
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A comparative metabolomic analysis reveals the metabolic variations among cartilage of Kashin-Beck disease and osteoarthritis [PDF]
Bone & Joint ResearchAims: The metabolic variations between the cartilage of osteoarthritis (OA) and Kashin-Beck disease (KBD) remain largely unknown. Our study aimed to address this by conducting a comparative analysis of the metabolic profiles present in the cartilage of ...
Hong Chang +9 more
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The Long‐term Efficacy of Total Knee Arthroplasty on End‐stage Kashin–Beck Disease of the Knee in Highland Tibetan Areas Patients: A Retrospective Study with 10‐Year Follow‐up [PDF]
Orthopaedic SurgeryObjective Despite the established success of total knee arthroplasty (TKA) with end‐stage osteoarthritis, there is a notable scarcity of research on its long‐term outcomes in individuals suffering from end‐stage Kashin–Beck disease (KBD).
Haocheng Sun +5 more
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