Results 31 to 40 of about 12,768 (245)

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin   +117 more
core   +1 more source

Genetic diversity of clinical isolates of Mycobacterium tuberculosis in Northeast of Iran [PDF]

Reviews in Clinical Medicine
Background: Mycobacterium tuberculosis is still one of the most dangerous human pathogens. Identification of the relationships between different clinical strains has remained a high priority for epidemiology research. Methods: In this study, we used MLSA
Samaneh Saedi, kiarash ghazvini, Masoud Youssefi, Hadi Safdar, saman soleimanpour, Parviz Afrough, Amir Azimian, hamid solgi, Masoud Keikha   +8 more
doaj   +1 more source

Regulation of the katG‐dpsA operon and the importance of KatG in survival of Burkholderia pseudomallei exposed to oxidative stress [PDF]

FEBS Letters, 2003
Homologues of the catalase‐peroxidase gene katG and the gene for the non‐specific DNA binding protein dpsA were identified downstream of oxyR in Burkholderia pseudomallei ...
Loprasert, Suvit, Whangsuk, Wirongrong, Sallabhan, Ratiboot, Mongkolsuk, Skorn   +3 more
openaire   +2 more sources

Molecular analysis of isoniazid and rifampin resistance in Mycobacterium tuberculosis isolates recovered from Barcelona. [PDF]

, 2016
We studied the presence of mutations in the whole katG gene and specific regions of the oxyR-ahpC and mabA-inhA regulatory region in 61 Mycobacterium tuberculosis isoniazid-resistant isolates.
Alcaide Fernández de Vega, Fernando, Aragón, Lina Marcela, Coll, Pere, Espasa, Mateo, Garrigó, Montserrat, González Martín, Julián, Manterola, Jose M., Orús, Pilar, Salvadó, Margarita   +8 more
core   +1 more source

Comparative genomic analysis of Geobacter sulfurreducens KN400, a strain with enhanced capacity for extracellular electron transfer and electricity production [PDF]

, 2012
Peer ...
Aklujkar, Muktak, Butler, Jessica E, Lovley, Derek R, Young, Nelson D   +3 more
core   +4 more sources

Mechanisms of Antibiotic Resistance and Novel Therapeutic Approaches for <i>Mycobacterium tuberculosis</i>: A Narrative Review With a Focus on Tuberculosis Mutations in Iran. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Tuberculosis, caused by Mycobacterium tuberculosis (M. tuberculosis), is a highly contagious disease and one of the leading causes of mortality globally. The emergence and dissemination of multidrug‐resistant (MDR) strains of M. tuberculosis have become a major concern, especially in developing countries.
Bodaghi AB, Shariati A, Shamseddin J, Bodaghi AB, Rezaei M, Farahani A.   +5 more
europepmc   +2 more sources

Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance. [PDF]

, 2019
INTRODUCTION: 2018 World Health Organization (WHO) guidelines for the treatment of isoniazid (H)-resistant (Hr) tuberculosis recommend a four-drug regimen: rifampicin (R), ethambutol (E), pyrazinamide (Z) and levofloxacin (Lfx), with or without H ([H]RZE-
Abbara, A, Abubakar, I, Alexander, E, Baker, LV, Barrett, JC, Booth, H, Bothamley, GH, Burgess, H, Cosgrove, C, Creer, DD, Davidson, JA, Dunleavy, A, Francis, M, Grp, LINH-RTBS, Gupta, U, Hamid, S, Harris, RJ, Haselden, BM, Holden, E, Kahr, V, Kon, OM, Kunst, H, Lalor, MK, Lipman, MC, Loebinger, MR, Loutet, MG, Lozewicz, S, Lynn, W, McHugh, TD, Milburn, HJ, Mohiyuddin, T, Palchaudhuri, P, Perrin, FM, Phillips, PPJ, Rahman, A, Schmok, E, Soobratty, MR, Stagg, HR, Taylor, L   +38 more
core   +4 more sources

Physical characterization of katG, encoding catalase HPI of Escherichia coli [PDF]

Gene, 1987
The gene encoding the bifunctional catalase-peroxidase HPI from Escherichia coli was located on a 3.8-kb HindIII fragment of the Clarke and Carbon plasmid pLC36-19 using transposon Tn5 insertions. This fragment was subcloned into the HindIII site of pAT153 to create pBT22. The size of the insert was reduced by BAL 31 digestion of one end to an apparent
B L, Triggs-Raine, P C, Loewen
openaire   +2 more sources

Molecular characterisation of mutations associated with resistance to first- and second-line drugs among Indonesian patients with tuberculosis

Journal of Taibah University Medical Sciences, 2020
الملخص: أهداف البحث: تهدف هذه الدراسة لتحديد الخصائص الجزيئية لتسلسل الجينات rpoB، katG، rrs وgyrA في السل الفطري التي تم عزلها من مجموعة من مرضى إندونيسيين يعانون من السل.
Faiqah F. Umar, PhD, Dirayah R. Husain, PhD, Mochammad M. Hatta, PhD, Rosdiana R. Natzir, PhD, Rizalinda S. Sjahril, PhD, Ressy R. Dwiyanti, PhD, Ade R. Junita, MD, Muhammad R. Primaguna, MD   +7 more
doaj   +1 more source

Mutations in rpoB and katG genes and the inhA operon in multidrug-resistant Mycobacterium tuberculosis isolates from Zambia

Journal of Global Antimicrobial Resistance, 2020
Objectives: It is established that resistance to rifampicin (RIF) in 90% of RIF-resistant Mycobacterium tuberculosis isolates is attributable to point mutations in the rpoB gene, whilst 50–95% of M. tuberculosis resistance to isoniazid (INH) is caused by
Eddie S. Solo, Chie Nakajima, Trevor Kaile, Precious Bwalya, Grace Mbulo, Yukari Fukushima, Sylvia Chila, Nanthan Kapata, Yogendra Shah, Yasuhiko Suzuki   +9 more
doaj   +1 more source