Structure - Activity Relationship of Mutant KatG from INH resistant Mycobacterium tuberculosis [PDF]
Journal of Pure and Applied Microbiology, 2017 Mutation in katG gene of Mycobacterium tuberculosis encoding catalase-peroxidase that damage its enzyme activities is well associated with isoniazid (INH) resistance. The katG gene from INH resistant strain of M.
Purkan Purkan +4 more
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KatG-Mediated Oxidation Leading to Reduced Susceptibility of Bacteria to Kanamycin [PDF]
ACS Omega, 2018 Abstract Resistance to antibiotics has become a serious problem for society, and there are increasing efforts to understand the reasons for and sources of resistance. Bacterial-encoded enzymes and transport systems, both innate and acquired, are the most frequent culprits for the development of resistance, although in Mycobacterium ...
Peter C. Loewen +6 more
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Redox Thermodynamics of the Ferric−Ferrous Couple of Wild-Type Synechocystis KatG and KatG(Y249F)
Biochemistry, 2006 Crystal structures and mass spectrometric analyses of catalase-peroxidases (KatGs) from different organisms revealed the existence of a peculiar distal Met-Tyr-Trp cross-link. The adduct appears to be important for the catalase but not the peroxidase activity of bifunctional KatG.
BELLEI, Marzia +4 more
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Tuberculosis in Sudan: A Comprehensive Narrative Review of Epidemiological Trends, Diagnosis, Drug Resistance, Challenges, and Data Gaps [PDF]
Health Science Reports, Volume 9, Issue 9, September 2026.ABSTRACT Background and Aims This narrative review aims to provide a comprehensive overview of tuberculosis (TB) in Sudan, focusing on prevalence, drug resistance patterns, and associated challenges while identifying knowledge gaps in scientific research and data needed for effective management.
Mohammad Azhar Kamal +3 more
wiley +2 more sources
Molecular Diagnostics for WHO Priority Bacterial Pathogens: A Bibliometric Mapping of Diagnostic Platforms, Resistance Markers, and Antimicrobial Resistance Research Trends [PDF]
MicrobiologyOpen, Volume 15, Issue 5, October 2026.This bibliometric mapping of 1746 publications (2000–2025) charts molecular diagnostics for WHO priority bacterial pathogens across platforms, targets, and resistance markers. Conventional PCR/NAAT and whole‐genome sequencing emerge as complementary core platforms, and the field evolves from targeted pathogen detection into an AMR‐centered ...
Selahattin Ünlü
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MOLECULAR GENETIC ANALYSIS AND SPECTRUM OF MUTATIONS IN KATG, INHA, RPOB GENES CODING DRUG RESISTANCE TO ISONIAZID AND RIFAMPICIN IN THOSE SUFFERING FROM TB/HIV CO-INFECTION [PDF]
Туберкулез и болезни лёгких, 2016 51 patients suffering from pulmonary tuberculosis with concurrent HIV infection (Group 1) had PCR testing in real time (ZAO Sintol, Moscow) of sputum samples in order to study the spectrum and prevalence of mutations in katG, inhA, rpoB genes coding drug
T. Yu. Salina +2 more
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Comparative study of catalase-peroxidases (KatGs) [PDF]
Archives of Biochemistry and Biophysics, 2008 Catalase-peroxidases or KatGs from seven different organisms, including Archaeoglobus fulgidus,Bacillus stearothermophilus, Burkholderia pseudomallei, Escherichia coli, Mycobacterium tuberculosis, Rhodobacter capsulatus and Synechocystis PCC 6803, have been characterized to provide a comparative picture of their respective properties. Collectively, the
Rahul, Singh +5 more
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KatG from Salmonella Typhimurium is a peroxynitritase [PDF]
FEBS Letters, 2010 Pathogenic bacteria elicit protective responses to oxidative and nitrosative stresses. Although such responses are generally distinct, it was recently reported in Mycobacterium tuberculosis that catalase–peroxidase (KatG), a classical defence against peroxides, also exhibits peroxynitritase activity.
McLean, Samantha +2 more
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Regulation of the katG‐dpsA operon and the importance of KatG in survival of Burkholderia pseudomallei exposed to oxidative stress [PDF]
FEBS Letters, 2003 Homologues of the catalase‐peroxidase gene katG and the gene for the non‐specific DNA binding protein dpsA were identified downstream of oxyR in Burkholderia pseudomallei ...
Loprasert, Suvit +3 more
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Nucleotide sequence of the Mycobacterium leprae katG region [PDF]
Journal of Bacteriology, 1997 Synthetic oligonucleotide primers based on the DNA sequence data of the Escherichia coli, Mycobacterium tuberculosis, and Mycobacterium intracellulare katG genes encoding the heme-containing enzyme catalase-peroxidase were used to amplify and analyze the Mycobacterium leprae katG region by PCR.
N, Nakata +4 more
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