Results 71 to 80 of about 12,768 (245)

Effect of temperature on Burkholderia pseudomallei growth, proteomic changes, motility and resistance to stress environments. [PDF]

, 2018
Burkholderia pseudomallei is a flagellated, gram-negative environmental bacterium that causes melioidosis, a severe infectious disease of humans and animals in tropical areas. We hypothesised that B.
Chantratita, Narisara, Paksanont, Suporn, Peacock, Sharon J, Pumirat, Pornpan, Sintiprungrat, Kitisak, Yimthin, Thatcha   +5 more
core   +1 more source

Virulence Regulation and Lifestyle Transitions: The Role of c‐di‐GMP and Two‐Component Systems in Erwinia amylovora and Their Evolutionary Context Within Enterobacterales

Molecular Plant Pathology, Volume 27, Issue 2, February 2026.
Erwinia amylovora infects apple blossoms by activating the T3SS, then spreads systemically via amylovoran‐mediated biofilms. Transitions between motile and sessile states are regulated by key two‐component systems and c‐di‐GMP. This review summarises infection biology, virulence factors, regulatory networks and evolutionary insights underlying fire ...
Dhirendra Niroula, Kalyani Bhandari, George W. Sundin, Janak R. Joshi   +3 more
wiley   +1 more source

Tuberculosis vaccine strain _Mycobacterium bovis_ BCG Russia is a natural _recA_ mutant [PDF]

, 2008
The current tuberculosis vaccine is a live vaccine derived from _Mycobacterium bovis_ and attenuated by serial _in vitro_ passaging. All vaccine substrains in use stem from one source, strain Bacille Calmette-Guérin.
Erik C. Boettger, Peter M. Keller, Peter Sander   +2 more
core   +1 more source

DETERMINACIÓN DE LA MUTACIÓN S315T DEL GEN KATG EN AISLADOS RESISTENTES A ISONIACIDA DE MYCOBACTERIUM TUBERCULOSIS MEDIANTE PCR-RFLP

Infectio, 2018
Objetive: To determine the S315T mutation of the katG gene in Mycobacterium tuberculosis isoniazid-resistant isolates by PCR-RFLP. Materials and Methods: Polymorphism analysis of 1054 and 630 bp products containing the S315T mutation of the katG gene ...
Jenny Sánchez-Domínguez
doaj   +1 more source

A proportion of mutations fixed in the genomes of in vitro selected isogenic drug-resistant Mycobacterium tuberculosis mutants can be detected as minority variants in the parent culture. [PDF]

, 2014
We studied genomic variation in a previously selected collection of isogenic Mycobacterium tuberculosis laboratory strains subjected to one or two rounds of antibiotic selection. Whole genome sequencing analysis identified eleven single, unique mutations
Anthony, Richard M, Bergval, Indra, Clark, Taane G, Coll, Francesc, de Ronde, Hans, Mallard, Kim, McNerney, Ruth, Pain, Arnab, Schuitema, Anja   +8 more
core   +2 more sources

Anthropogenic Disruption Versus Natural Restoration: Enterobacter cloacae‐Driven Barnacle Larval Settlement and Its Mitigation via Natural Bacteriophages

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
Anthropogenic‐derived E. cloacae colonises marine cooling water systems, where chlorine exposure drives cross‐resistance and enhances biofilm formation, creating hotspots for barnacle larval settlement. This work reveals a previously unrecognised mechanism linking microbial pollution to marine biofouling.
Atif Khan, Akash Saha, Hiren M. Joshi
wiley   +1 more source

A switch and a failsafe: KatG’s mechanism for preservation of catalase activity using a conformationally dynamic Arg and an active-site Trp

Frontiers in Chemical Biology
Many novel structural features impart a robust catalase activity to KatG that is absent from all other members of its superfamily. The conformationally dynamic “Arg switch” and oxidizable “proximal Trp” have both figured prominently in investigations of ...
Hui Xu, Jessica R. Kenneson, Laura E. Minton, Douglas C. Goodwin   +3 more
doaj   +1 more source

Transcriptional profiles of Burkholderia pseudomallei reveal the direct and indirect roles of Sigma E under oxidative stress conditions [PDF]

, 2016
This is the final version of the article. Available from BioMed Central via the DOI in this record.BACKGROUND: Burkholderia pseudomallei, the causative agent of melioidosis, is a Gram-negative bacterium widely distributed in soil and water in endemic ...
Hemsley, CM, Jitprasutwit, S, Juntawieng, N, Korbsrisate, S, Ong, C, Ooi, WF, Tan, P, Titball, RW, Vattanaviboon, P   +8 more
core   +1 more source

Analysis of Heme Structural Heterogeneity in Mycobacterium tuberculosis Catalase-Peroxidase (KatG) [PDF]

Journal of Biological Chemistry, 2003
Mycobacterium tuberculosis catalase-peroxidase (KatG) is a heme enzyme considered important for virulence, which is also responsible for activation of the anti-tuberculosis pro-drug isoniazid. Here, we present an analysis of heterogeneity in KatG heme structure using optical, resonance Raman, and EPR spectroscopy.
Salem, Chouchane, Stefania, Girotto, Sofia, Kapetanaki, Johannes P M, Schelvis, Shengwei, Yu, Richard S, Magliozzo   +5 more
openaire   +2 more sources

Structural insights for enhanced ROS detoxification of eKatE, a recently identified catalase in atypical E. coli

The FEBS Journal, Volume 293, Issue 1, Page 196-219, January 2026.
We revealed the crystal structure of eKatE from atypical E. coli. eKatE exhibits a hydrogen‐peroxide‐sensitive major channel, a stabilized dimeric interface, an unusual covalent bond between C392 and Y415, and other distinctive features. These structural features contribute to its enhanced catalase activity compared to KatE in typical E.
Eunhee Koh, Youngki Yoo, Mi Young Yoon, Myung Kyung Choi, Uijin Kim, Jun Bae Park, Sang Sun Yoon, Hyun‐Soo Cho   +7 more
wiley   +1 more source