KCC2 expression levels are reduced in post mortem brain tissue of Rett syndrome patients
Rett Syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG binding protein 2 (MECP2) gene. Deficient K+-Cl—co-transporter 2 (KCC2) expression is suggested to play a key role in the neurodevelopmental delay in RTT patients’
Lisa Hinz+2 more
doaj +1 more source
The Neuron-specific K-Cl Cotransporter, KCC2 [PDF]
Jeffery Williams+4 more
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Acta Paediatrica, Volume 113, Issue 10, Page 2197-2198, October 2024.
Elisabeth Fernell
wiley +1 more source
The effect of repeated stress on KCC2 and NKCC1 immunoreactivity in the hippocampus of female mice
K+–Cl− co-transporter (KCC2) and Na+–K+–2Cl− co-transporter (NKCC1) are the main regulators of neuronal intracellular chloride concentration; altered expression patterns of KCC2 and NKCC1 have been reported in several neurodegenerative diseases.
Takao Tsukahara+4 more
doaj
Heterogeneous Expression of the Potassium-Chloride Cotransporter KCC2 in Gonadotropin-Releasing Hormone Neurons of the Adult Mouse [PDF]
Sarah Leupen+3 more
openalex +1 more source
Mechanism of Activity-Dependent Downregulation of the Neuron-Specific K-Cl Cotransporter KCC2 [PDF]
Claudio Rivera+9 more
openalex +1 more source
Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission
The K-Cl co-transporter KCC2 plays multiple roles in the physiology of central neurons and alterations of its function and/or expression are associated with several neurological conditions.
Ingrid eChamma+3 more
doaj +1 more source
Differential distribution of the KCl cotransporter KCC2 in thalamic relay and reticular nuclei [PDF]
Péter Barthó+3 more
openalex +1 more source
Brain‐type creatine kinase activates neuron‐specific K+‐Cl– co‐transporter KCC2 [PDF]
Kōichi Inoue+3 more
openalex +1 more source
KCC2 expression in immature rat cortical neurons is sufficient to switch the polarity of GABA responses [PDF]
Hanmi Lee+4 more
openalex +1 more source