Results 181 to 190 of about 35,325 (217)

Oxidative Stress and the KEAP1/NRF2 Axis in Saphenous Vein: Implications for Graft Patency. [PDF]

Cells
Layton GR, Marston E, Musa HL, Ladak S, Copperwheat A, Oluwanifemi A, Antoun I, Zakkar M.   +7 more
europepmc   +1 more source

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

Phytotherapy Research, Volume 40, Issue 8, Page 5071-5089, August 2026.
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang, YongJun Du, Yanmei Hou, Liangliang Hao, Zhen Chen, Haoyang Xie, Chuantao Zhang, Lei Li   +7 more
wiley   +1 more source

Comprehensive metabolomic profiling of Egyptian Salvia species reveals promising leads for chemopreventive and anti-inflammatory drug development: In vitro and In silico study. [PDF]

Sci Rep
Hamed AR, Ali SK, Abdel-Halim SA, Bata SM, Hegazi NM, Mohamed TA, Hegazy MF.   +6 more
europepmc   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, Volume 40, Issue 8, Page 5119-5131, August 2026.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source

NUP62 promotes breast cancer progression and inhibits ferroptosis by stabilizing NRF2 in a KEAP1-dependent way. [PDF]

iScience
Qiu Z, Lin Y, Chen S, Cao W, Yang J, Li R, Chen Y, Yao X, Fu S, Jin N.   +9 more
europepmc   +1 more source

Advancing Treatment of Degenerative Eye Diseases at the Nanoscale

Smart Medicine, Volume 5, Issue 4, August 2026.
Nanotherapeutics possess the potential to overcome longstanding bottlenecks in treating degenerative ophthalmic diseases. With a highly tunable surface chemistry, nanotechnology platforms can be customized to navigate specific anatomical barriers in the eye and target pathways of diseases.
Li Yao Jin, Evashiniee G. P. Selvam, Qinsong Mei, Chi D. Luu, Yeannie H. Y. Yap, Daniel B. L. Teh   +5 more
wiley   +1 more source

Novel antioxidant peptides from chicken bone hydrolysate: Identification, structure-activity relationship and cytoprotective effects against oxidative stress in HaCaT cells. [PDF]

Food Chem X
Jin Y, Zhang J, Miao J, Peng Z, Liu Y, Zhao Z.   +5 more
europepmc   +1 more source

South African Herbal Teas and Diabetes‐Mediated Mitochondrial Dysfunction: Emerging Evidence and Mechanistic Insights

Journal of Food Science, Volume 91, Issue 8, August 2026.
ABSTRACT Type 2 diabetes mellitus (T2DM) is a central component of the metabolic syndrome (MetS) and is associated with underlying mitochondrial dysfunction. Disruption of mitochondrial homeostasis impairs cellular energy metabolism and contributes to the overproduction of reactive oxygen species (ROS), leading to oxidative stress, chronic inflammation,
Shanika Reddy, Naeem Sheik Abdul, Taskeen Fathima Docrat, Jeanine Marnewick   +3 more
wiley   +1 more source

Nrf2 Levels in Human Semen and Spermatozoa: Association with F₂-Isoprostanes as Markers of Lipid Peroxidation. [PDF]

Int J Mol Sci
Moretti E, Signorini C, Liguori L, Leoni E, Collodel G.   +4 more
europepmc   +1 more source

<i>Camellia oleifera</i> Seed Cake Extract Ameliorates Hyperuricemia and Renal Injury by Modulating Uric Acid Metabolism, Nrf2/Keap1 Pathway, and NLRP3 Inflammasome in Mice. [PDF]

Food Sci Nutr
Mai L, Xie Y, Zhang Y, Ni C, Xu Y, Xu L, Lin G, Lin Y, Su Z, Wang J, Ren M.   +10 more
europepmc   +1 more source