Discovery of a novel Nrf2 activator that modulates mitochondrial function in neurons by regulating DHRS3-Nrf2 interaction after ischemic stroke. [PDF]
Sun X +14 more
europepmc +1 more source
Melatonin ameliorates TNFα-induced oral epithelial cell inflammation via Keap1-Nrf2 axis modulation. [PDF]
Wang S +6 more
europepmc +1 more source
Capicua mediates interleukin-2 withdrawal-induced death of activated CD8<sup>+</sup> T cells. [PDF]
Shi JG +5 more
europepmc +1 more source
TARGETING THE NRF2/KEAP1 INTERACTION
The Nrf2/Keap1 protein-protein interaction (PPI) regulates activity of the Nrf2 antioxidant and anti-inflammatory pathway. The transcription factor Nrf2 has been found to be a key mediator in the resolution of inflammation and the progression of chronic diseases.
openaire +1 more source
Butyrate protects against Klebsiella pneumoniae-induced oxidative stress in alveolar macrophages via p62-Keap1-Nrf2 pathway. [PDF]
Meng B +16 more
europepmc +1 more source
Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice [PDF]
Allagnat +71 more
core +2 more sources
CILP Inhibits hyaline cartilage fibrosis and chondrocyte ferroptosis via keap1-Nrf2 axis in early osteoarthritis exercise therapy. [PDF]
Jia S +10 more
europepmc +1 more source
Erythropoietin preserves outer blood-retinal barrier integrity in diabetic retinopathy via AMPK-dependent autophagy and Nrf2 signaling. [PDF]
Jang HY +5 more
europepmc +1 more source
METTL3-driven m<sup>6</sup>A modification of NLRC5 promotes renal fibrosis in chronic kidney disease through Keap1/Nrf2/ARE signaling pathway. [PDF]
Xu M +7 more
europepmc +1 more source
Oxidative Stress and Ultrastructural Changes in Laminar Tissue of Dairy Cows with Acute Laminitis Induced by Oligofructose Overload. [PDF]
Hayat MA +5 more
europepmc +1 more source

