Results 211 to 220 of about 53,484 (262)

SMURF2 attenuates NRF2-driven tumor progression by acting as a nuclear brake on NRF2 during cellular stress. [PDF]

Redox Biol
Xu W, Dong L, Li J, Fan S, Wang Y, Xia Q.   +5 more
europepmc   +1 more source

EGFR inhibitor-resistant lung cancers exhibit collateral sensitivity to a covalent, cysteine-independent KEAP1 oligomerizing molecular bridge. [PDF]

Nat Commun
Bassil CF, Dillon K, Anderson GR, Mayro B, Askin KN, Winter PS, Harry S, Gruber S, Hall TM, Hoj JP, Cerda-Smith C, Hutchinson HM, Killarney ST, Heffernan A, Teddy C, Singleton KR, Qin L, Jubien-Girard K, Favreau C, Robert G, Tivon B, Livnah E, London N, Benhida R, Auberger P, Pendergast AM, Bar-Peled L, Lonard DM, Martin AR, Puissant A, Wood KC.   +30 more
europepmc   +1 more source

Gentiopicroside alleviates type 2 diabetes mellitus by attenuating oxidative stress and reshaping gut microbiota in high-fat diet and streptozotocin-induced mice. [PDF]

Front Nutr
Wang X, Long D, Peng X, Wu L, Xie Q, Luo S, Li H, Zhou M, Zhou T.   +8 more
europepmc   +1 more source

The electrophilic metabolite of kynurenine, kynurenine-CKA, requires C151 in Keap1 to derepress Nrf2. [PDF]

Redox Biol
Feng J, Carreño M, Jung H, Dayalan Naidu S, Arroyo-Diaz N, Ang AD, Kulkarni B, Kisielewski D, Suzuki T, Yamamoto M, Hayes JD, Honda T, Wilson L, Leon-Ruiz B, Eggler AL, Vitturi DA, Dinkova-Kostova AT.   +16 more
europepmc   +1 more source

The Role of Protein Kinases in the Management of Oncological Diseases by Acting on Ferroptotic Pathways. [PDF]

Int J Mol Sci
Folgiero V, Caforio M.
europepmc   +1 more source

Ginsenoside Rh4 Triggers Ferroptosis in Lung Cancer: Targeting <i>KEAP1</i>/<i>NRF2</i>/<i>HO-1</i> and Remodeling Gut Microbiota for Butyrate-Mediated <i>ATF3</i> Activation. [PDF]

Int J Mol Sci
Zhu Q, Xu W, Yang G, Gao Y, Zhao Y, Zhao Z, Kang Y, Li S, Zhao L.   +8 more
europepmc   +1 more source

Alisol F 24-acetate attenuated metabolic dysfunction-associated steatohepatitis by targeting the KEAP1/NRF2-mediated macrophage pyroptosis. [PDF]

Chin Med
Dong Z, Huang K, Wu W, Xing L, Zhang Y, Zhang X, Yang W, Zhao K.   +7 more
europepmc   +1 more source

Discovery of ferulic acid carbamate derivatives as dual-targeting agents of BuChE and Nrf2 for Alzheimer's disease. [PDF]

J Enzyme Inhib Med Chem
Lao K, Li Y, Xiao Y, Sun Y, Dai Y, Li H, Yang Y, Zhang Y, Wang J, Li W, Gou X, Guan L.   +11 more
europepmc   +1 more source