Results 201 to 210 of about 45,202 (305)

Discovery and molecular insights of a novel pea-derived antioxidant peptide: From quantum chemical insights to oxidative stability of walnut oil. [PDF]

Food Chem X
Peng J, Qi T, Lin Q, Zhang X, Wang Y, Bao Y.   +5 more
europepmc   +1 more source

Bromo-desthiobiotin (Br-DTB) tag for unbiased profiling and identification of chemical modifications. [PDF]

RSC Chem Biol
Palai BB, Ramirez DH, Deng C, de Luna Vitorino FN, Zhao C, Zhu D, Lv D, Garcia BA, Lin Z.   +8 more
europepmc   +1 more source

Astragaloside IV and Ferroptosis Modulation in Pathological Cardiac Hypertrophy: Current Evidence, an Integrative Hypothesis, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Pathological cardiac hypertrophy is initially an adaptive response to sustained mechanical, neurohormonal, or metabolic stress; however, it can progress to fibrosis, contractile dysfunction, arrhythmia, and heart failure. Ferroptosis is a type of regulated cell death caused by iron‐dependent phospholipid peroxidation.
Pengbo Liu, Yongzhi Deng
wiley   +1 more source

Therapeutic gases and the Nrf2/Keap1 pathway: direct thiol modification vs . indirect modulation. [PDF]

Med Gas Res
Xiao T, Xia C, Huang L, Li Y, Liu M, Zhao P, Ma X, Xie F.   +7 more
europepmc   +1 more source

METTL7B‐Mediated m6A Modification of PLEKHA4 Suppresses Ferroptosis via Reducing AURKA Ubiquitination to Promote Papillary Thyroid Cancer Progression

Cancer Medicine, Volume 15, Issue 11, November 2026.
In PTC cells, METTL7B stabilizes PLEKHA4 mRNA through m6A modification; upregulated PLEKHA4 binds KLHL12 and inhibits KLHL12‐mediated ubiquitination and degradation of AURKA, thereby stabilizing AURKA protein. Elevated AURKA suppresses ferroptosis by upregulating GPX4 and xCT while downregulating ACSL4, leading to ferroptosis resistance and enhanced ...
Wei Lin, Kunlin Wu, Jinshu Chen, Zhaomei Yu, Huihao Zhang, Xiangjin Chen   +5 more
wiley   +1 more source

Disruption of p62 ubiquitination by α-methylene-γ-butyrolactone enhances Keap1 lysosomal degradation for ulcerative colitis therapy. [PDF]

Redox Biol
Linghu KG, Wang D, Zhang T, Jiang F, Wu L, Pan D, Chen Y, Tao L, Lin L, Yu H, Du Q, Pan W, Shen X.   +12 more
europepmc   +1 more source

High Level of Component C1q Binding Protein (C1QBP) is Associated With Poor Prognosis and Dysfunction of Mast Cells in Lung Adenocarcinoma

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Component C1q binding protein (C1QBP) is known as an important regulator of mitochondrial plasticity and is involved in antitumor immune response in cancers. Nevertheless, its role in lung adenocarcinoma (LUAD) still remains largely unknown.
Wei Li, Guangnan Huang, Lizhong Zeng, Wenhui Dang, Ting Jiao, Yonghong Zhang, Mengying Zhang, Shuru Zhou, Liping Chen, Shuanying Yang   +9 more
wiley   +1 more source

LC-MS/MS-based peptide identification, molecular simulations, and biological validation for targeted discovery of antioxidant peptides from large yellow croaker. [PDF]

Food Chem X
Wu X, Liu F, Li D, Zhang J, Zhuang Y, Huang W.   +5 more
europepmc   +1 more source

Preliminary Evidence Suggests the Transcriptomic Response of Tricolored Bats to White‐Nose Syndrome Is Similar but Not Identical to That of Little Brown Bats

Ecology and Evolution, Volume 16, Issue 11, November 2026.
In this study, we evaluate gene expression of tricolored bats in response to white‐nose syndrome and compare it to that of little brown bats. We found that tricolored bats show evidence of a similar transcriptomic immune response to little brown bats, sharing pathways and some genes.
Robert E. Kwait, Evan A. Eskew, Maanasvi Balasubramanian, Sarah A. Gignoux‐Wolfsohn, Malin L. Pinsky, Brooke Maslo   +5 more
wiley   +1 more source

Integrated In Silico Discovery of Thymoquinone Analogs Targeting the Keap1-Nrf2 Pathway for Amyotrophic Lateral Sclerosis Therapy. [PDF]

ChemistryOpen
Nalicho JC, Mabeyo PE, Paluch AS, Paul L.   +3 more
europepmc   +1 more source