Results 231 to 240 of about 50,990 (303)

Curcumin improves bladder dysfunction in diabetic rats by attenuating oxidative stress via the Keap1/NRF2/HO-1 pathway. [PDF]

Transl Androl Urol
Zheng JH, Zhang DF, Li HR, Jin RY, Chen H, Zhang HY.   +5 more
europepmc   +1 more source

Toosendanin Alleviates Cerebral Ischemia/Reperfusion Injury via Inhibiting Neural Ferroptosis Through Lipid Metabolic Reprogramming in MCAO Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Post‐stroke administration of TSN significantly reduced infarct volume, neuroinflammation, and improved functional recovery of MCAO mice. TSN alleviated neural oxidative stress, lipid peroxidation, and ferroptosis in MCAO mice. TSN modulated the infiltration of immune cells in MCAO mice in vivo and T cell differentiation in vitro.
Xinyun Li, Zhiyong Zhao, Jingting Zhao, Xiangming Ye, Zhenfei Xiong, Jiejin Zhao   +5 more
wiley   +1 more source

Polyphyllin B induces ferroptosis in triple-negative breast cancer by inactivating NRF2. [PDF]

Front Pharmacol
Deng P, Zhu S, Wu Y, Fang Z, Zhang A, Zhang D, Hu X, Zhou X.   +7 more
europepmc   +1 more source

Upregulated PKM2 Protects Dopaminergic Neurons From Oxidative Damage Through Nrf2 Transactivation in an MPTP‐Induced Mouse Model of Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Oxidative stress induced by MPTP promotes hnRNP A1/A2–dependent alternative splicing toward PKM2 in dopaminergic neurons. Elevated PKM2 transactivates Nrf2, enhances antioxidant gene expression, and protects neurons from oxidative damage and degeneration.
Meng Mei, Qian‐qian Miao, Meng‐ke Li, Hao‐ran Wang, Jian‐hua Ding, Gang Hu, Yao Wei   +6 more
wiley   +1 more source

Unveiling novel antioxidant peptides from silver carp (<i>Hypophthalmichthys molitrix</i>) bone collagen and underlying multi-dimensional mechanism by integrating <i>in silico</i>, <i>in vitro</i>, and <i>in cellulo</i> approaches. [PDF]

Food Chem X
Mei Y, Lin F, Xie R, Chen J, Hu J, Chen W, Du H, Hao G, Li S, Zhang J.   +9 more
europepmc   +1 more source

Lipid oxidation and nitration products as activators of cytoprotective Nrf2 signaling in the endothelium [PDF]

Kansanen, Emilia
core  

Fusobacterium nucleatum in cancer: Interactions with microbiota, tumour colonisation and cancer progression

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
F. nucleatum colonises tumours through mucosal translocation, adjacent‐tissue migration and hematogenous dissemination. It promotes cancer progression via adhesion, inflammation, immune evasion, epigenetic remodelling and metastasis. Its effects on therapy response are tumour‐context dependent. Microbiome‐guided targeting may enable precision oncology.
Feng Zhao, Rui An, Shaobo Yu, Yilei Ma, Wangwang Liu, Caixia Sheng, Xinyou Xie, Jun Zhang   +7 more
wiley   +1 more source

Isoliquiritigenin, a Bioactive Blood Component Derived from Licorice, Activates Nrf2 Enzymes to Confer Protection Against Radiation-Induced Nerve Injury. [PDF]

Antioxidants (Basel)
Yao J, Ma J, Lin H, Shao C, Liu X, Jin X.   +5 more
europepmc   +1 more source