Results 251 to 260 of about 50,990 (303)

KRAS G12C inhibitor outcomes in advanced non-small cell lung cancer by smoking history, performance status, and KEAP1 mutation status. [PDF]

Cancer Treat Res Commun
Xu Z, Aredo JV, Su CC, Myall NJ, Roy M, Ramchandran KJ, Wakelee HA, Neal JW.   +7 more
europepmc   +1 more source

Combined Anserine/Carnosine Exerts Anti‐Hyperuricemic, Nephroprotective, and Gut Microbiota‐Modulating Effects in Hyperuricemia Mice

Food Bioengineering, Volume 5, Issue 2, Page 194-208, June 2026.
Mixed carnosine and anserine significantly reduce serum uric acid, protect the kidneys, and modulate gut microbiota, demonstrating potent therapeutic potential against hyperuricemia. ABSTRACT The anti‐hyperuricemic, nephroprotective, and gut microbiota modulation effects of mixed carnosine and anserine (MAC) with the fixed ratio of 10:1 were evaluated ...
Jingjing Huang, Zheng Dang, Yuzhi Zhang, Haisheng Lin, Lei Du, Jie Zhang, Li Zhao, William T. H. Chang, Xiang‐Ru Kong, Wei‐Ting Tseng, Jingli Xie   +10 more
wiley   +1 more source

Dietary Spermidine Mitigates Radiation‐Induced Intestinal Injury by Reshaping the Microbiota‐Barrier‐Inflammation Axis

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Spermidine (SPD) protects against radiation‐induced intestinal injury by activating the Nrf2 pathway to reduce oxidative stress and DNA damage, enhancing tight junction proteins to restore barrier integrity, and remodeling gut microbiota (enriching butyrate‐producing bacteria while suppressing pathogens).
Song Li, Yanjiang Liu, Minglin Jiang, Yu Zha, Chang Liu, Hongtao Luo, Kejian Pan, Tao Zhang, Xiaolin Ren   +8 more
wiley   +1 more source

Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao, Xiao‐li Dong, Rui‐ting Li, Qu‐huan Ma, Xiao‐feng Shi   +4 more
wiley   +1 more source

The Chemical Structures, Neuroprotective Effects, Structure–Activity Relationships, and Applications of Flavonoids, Phenolic Acids, Terpenoids, and Sterols in Dandelion: A Review

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This review systematically summarizes the chemical structures and structure–activity relationships of key bioactive compounds in dandelion, including flavonoids, phenolic acids, terpenoids, and sterols. It highlights their neuroprotective mechanisms against neuroinflammation and oxidative stress, while outlining their promising dual applications in the
Hongye Li, Bingchan Qu, Jiasu Wu, Menghan Sun, Youlin Xue, Tiejing Li, Chang Tan, Shan Wang, Chong Ning, Chongting Guo   +9 more
wiley   +1 more source

Alkannin Protects Against UVB-Induced Skin Photoaging by Targeting Keap1 to Activate the Nrf2/HO-1 Pathway. [PDF]

Molecules
Wu Q, Tao F, Zhang N, Li Y, Li S.
europepmc   +1 more source

Virgin Coconut Oil Attenuates Diabetic Kidney Disease via Gut Microbiota‐Metabolism‐Inflammation Axis Modulation in Type 2 Diabetic Mice

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study elucidates the multi‐targeted mechanisms of Virgin Coconut Oil (CO) as a dietary intervention for ameliorating Diabetic Kidney Disease (DKD). High‐purity medium‐chain fatty acids (MCFAs, primarily octanoic acid [C8:0] and decanoic acid [C10:0]) in CO significantly remodel the gut microbiota by enriching short‐chain fatty acid (SCFA ...
Keke Shao, Yun Cao, Ruiqi Gao, Xueyun Dong, Xuehui Liu, Hao Xu, Yunhan Xie, Linlin Xu, Jiayuan He, Min Chen, Leilei Zhang, Asmaa Ali, Liang Wu, Pingping Wang   +13 more
wiley   +1 more source

Celastrol Ameliorates Renal Injury in Spontaneously Hypertensive Rats by Activating the Nrf2/Ho-1 Signaling Pathway to Alleviate Oxidative Stress. [PDF]

Int J Mol Sci
Deng Y, Wang J, Liu X, Wang X, Li H, Gu B, Zhang M, Wang R, Yang Y.   +8 more
europepmc   +1 more source

Liensinine Ameliorating Oxidative Damage to Vascular Endothelium In Vitro via Upregulating eNOS and Nrf2/HO‐1 Signaling

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
The present studies of network pharmacology, molecular docking and molecular dynamics simulation indicated that liensinine might ameliorate oxidative damage to vascular endothelium (ODVE) by regulating the targets of Nrf2, which is encoded by the NFE2L2 gene. Then the in vitro study further showed that liensinine exhibited an obvious protection against
Feng Gao, Fengjiao Deng, Qiaowei Du, Tianya Xia, Yayi Deng, Shuang Liu, Bin Yu, Chenxiao Shan   +7 more
wiley   +1 more source