Resistance of corneal RFUVA-cross-linked collagens and small leucine-rich proteoglycans to degradation by matrix metalloproteinases [PDF]
, 2013 Purpose. Extracellular matrix metalloproteinases (MMPs) are thought to play a crucial role in corneal degradation associated with the pathological progression of keratoconus.
Conrad, Gary W. +4 more
core +1 more source
In Vitro Engineered ECM‐incorporated Hydrogels for Osteochondral Tissue Repair: A Cell‐Free Approach
Advanced Healthcare Materials, Volume 14, Issue 4, February 7, 2025.Figure highlights the fabrication process of the osteogenic and chondrogenic decellularized extracellular matrix that can be used for repairing osteochondral defects. 3D osteochondral plugs containing GelMA and the bioactive decellularized extracellular matrix can be prepared by 3D printing.
Ali Coyle +5 more
wiley +1 more source
Histopathologic and immunohistochemical features of capsular tissue around failed Ahmed glaucoma valves. [PDF]
PLoS ONE, 2017 Impervious encapsulation around Ahmed glaucoma valve (AGV) results in surgical failure raising intraocular pressure (IOP). Dysregulation of extracellular matrix (ECM) molecules and cellular factors might contribute to increased hydraulic resistance to ...
Alka Mahale +8 more
doaj +1 more source
Long-term effects of hydrogen sulfide on the anabolic-catabolic balance of articular cartilage in vitro [PDF]
, 2017 [Abstract] Healthy cartilage maintenance relies on an equilibrium among the anabolic and catabolic processes in chondrocytes. With the onset of osteoarthritis (OA), increased interleukin (IL)-1β levels induce an inhibition of the synthesis of ...
Blanco García, Francisco J +7 more
core +2 more sources
Role of the Extracellular Matrix in Cancer: Insights into Tumor Progression and Therapy
Advanced Therapeutics, Volume 8, Issue 2, February 2025.The extracellular matrix (ECM) is pivotal in cancer progression, influencing tumor growth, metastasis, and therapy resistance. This paper explores ECM remodeling, highlighting components like collagens and proteoglycans, their impact on immune evasion, and emerging therapies targeting ECM mechanics and composition.
Nimeet Desai +8 more
wiley +1 more source
Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor. [PDF]
, 1991 Lymphocyte attachment to high endothelial venules within lymph nodes is mediated by the peripheral lymph node homing receptor (pnHR), originally defined on mouse lymphocytes by the MEL-14 mAb.
Fennie, C +4 more
core
Quantification of sulfated polysaccharides in mouse and rat plasma by the Heparin Red mix-and-read fluorescence assay [PDF]
arXiv, 2017 Sulfated polysaccharides constitute a large and complex group of macromolecules which possess a wide range of important biological properties. Many of them hold promise as new therapeutics, but determination of their blood levels during pharmacokinetic studies can be challenging.
arxiv
Eggshell‐Based Unconventional Biomaterials for Medical Applications
Advanced NanoBiomed Research, Volume 5, Issue 2, February 2025.Eggshells are an abundant and sustainable resource with exceptional mechanical and morphological characteristics. Their unique properties emphasize the versatility potential of eggshell‐based biomaterials in developing cost‐effective, nature‐inspired solutions suited for innovations in hard and soft tissue repair, drug delivery systems, and biosensor ...
Maria Eduarda Torres Gouveia +3 more
wiley +1 more source
Transient Sulfate Aerosols as a Signature of Exoplanet Volcanism [PDF]
, 2015 Geological activity is thought to be important for the origin of life and for maintaining planetary habitability. We show that transient sulfate aerosols could be a signature of exoplanet volcanism, and therefore a geologically active world. A detection of transient aerosols, if linked to volcanism, could thus aid in habitability evaluations of the ...
arxiv +1 more source
Aberrant Expression of TFF1, TFF2, and PDX1 and Their Diagnostic Value in Lobular Endocervical Glandular Hyperplasia [PDF]
, 2011 Lobular endocervical glandular hyperplasia (LEGH) is a distinct benign glandular lesion expressing gastric gland mucous cell-type mucin (N-acetylglucosaminal -> 4galactose -> R [GlcNAc alpha 1 -> 4Gal -> R]).
Harada, Oi +4 more
core +1 more source