Results 91 to 100 of about 10,759 (233)

Long-term effects of hydrogen sulfide on the anabolic-catabolic balance of articular cartilage in vitro [PDF]

, 2017
[Abstract] Healthy cartilage maintenance relies on an equilibrium among the anabolic and catabolic processes in chondrocytes. With the onset of osteoarthritis (OA), increased interleukin (IL)-1β levels induce an inhibition of the synthesis of ...
Blanco García, Francisco J, Burguera, Elena F., Díaz-Prado, Silvia, Gato Calvo, Lucía, Hermida Gómez, Tamara, Meijide-Faílde, Rosa, Vaamonde-García, Carlos, Vela-Anero, Á.   +7 more
core   +2 more sources

Aggrecan structure in amphibian cartilage

Brazilian Journal of Medical and Biological Research, 2000
The structure of the large proteoglycan present in the bullfrog epiphyseal cartilage was studied by immunochemical and biochemical methods. The isolated monomer showed a polydisperse behavior on Sepharose CL2B, with a peak at Kav = 0.14.
Covizi D.Z., Carvalho H.F.
doaj  

Histopathologic and immunohistochemical features of capsular tissue around failed Ahmed glaucoma valves. [PDF]

PLoS ONE, 2017
Impervious encapsulation around Ahmed glaucoma valve (AGV) results in surgical failure raising intraocular pressure (IOP). Dysregulation of extracellular matrix (ECM) molecules and cellular factors might contribute to increased hydraulic resistance to ...
Alka Mahale, Fatma Fikri, Khitam Al Hati, Sami Al Shahwan, Ibrahim Al Jadaan, Hind Al Katan, Rajiv Khandekar, Azza Maktabi, Deepak P Edward   +8 more
doaj   +1 more source

The elusive scleral cartilages: Comparative anatomy and development in teleosts and avians

The Anatomical Record, Volume 308, Issue 7, Page 1838-1850, July 2025.
Abstract The sclera of all vertebrate eyes is comprised of connective tissue, with some organisms developing cartilage within this tissue. A review of the cartilages that have been described in the vertebrate sclera and their anatomical relationships is discussed together with their potential homology.
Tamara A. Franz‐Odendaal
wiley   +1 more source

Keratan Sulfate Glycosaminoglycans in Murine Eosinophil-specific Granules [PDF]

Journal of Histochemistry & Cytochemistry, 1999
We examined the presence of sialyl glycoconjugates in specific granules from murine bone marrow eosinophils. Lectin cytochemistry using Maackia amurensis lectin II (MAL II) specific for sialyl α-2,3 galactose residues demonstrated positive labeling in both immature and mature specific granules. Pretreatment with Clostridium neuraminidase or keratanase
Yukifumi Nawa, Shinichiro Tsuyama, Fusayoshi Murata, Dan-Ha Yang, Jun Ohmori   +4 more
openaire   +3 more sources

Enzyme Replacement Therapy With Elosulfase Alfa Decreases Storage of Glycosaminoglycan in White Blood Cells of Patients With Morquio A Syndrome

Journal of Inborn Errors of Metabolism and Screening, 2015
Mucopolysaccharidosis IVA (MPS IVA; Morquio A syndrome) is a lysosomal storage disorder caused by a deficient N-acetylgalactosamine-6-sulfate sulfatase activity, leading to cellular storage of undegraded keratan sulfate.
Guilherme Baldo PhD, Fabiano Poswar MD, Andressa Federhen MSc, Camila Bittar MD, Rejane Gus PhD, Fernanda Bender MSc, Roberto Giugliani MD, PhD   +6 more
doaj   +1 more source

Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model

Macromolecular Bioscience, Volume 25, Issue 7, July 2025.
This study reports on 3D‐printed methacrylated gelatin (GelMA) implants designed to serve as corneal stroma substitutes. The implants are characterized for their transparency, mechanical strength, and cytocompatibility. In vivo tests on rabbits demonstrate successful integration, with histopathological analysis showing tissue regeneration, appropriate ...
Deniz Basoz, Aslihan Akalinli, Senem Buyuksungur, A. R. Cenk Celebi, Deniz Yucel, Nesrin Hasirci, Vasif Hasirci   +6 more
wiley   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, Volume 19, Issue 6, Page 1707-1724, June 2025.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Marine origin polysaccharides in drug delivery systems [PDF]

, 2016
Oceans are a vast source of natural substances. In them, we find various compounds with wide biotechnological and biomedical applicabilities. The exploitation of the sea as a renewable source of biocompounds can have a positive impact on the development ...
Bansal, Contreras-Ruiz, Costa, Jimeno, João Mano, Kim, Krebs, Matias Cardoso, Mohammad, Panlasigui, Roy, Rui Costa, Sezer, Silva, Uchimura, Valoti   +15 more
core   +2 more sources

Transcriptional Changes in Cumulus Cells During In Vitro Maturation of Human Oocytes

Molecular Reproduction and Development, Volume 92, Issue 6, June 2025.
ABSTRACT This study assessed transcriptional changes in human cumulus cells (CCs) during oocyte maturation In Vitro. CCs were collected from 25 cumulus‐oocyte complexes derived from surplus ovarian medulla tissue of eight women (mean age 29 years, range 19–36) undergoing ovarian tissue cryopreservation without ovarian stimulation.
Jesús Cadenas, Cristina Subiran Adrados, Stine Gry Kristensen, Kirsten Tryde Macklon, Vinnie Hornshøj Greve, Jens Fedder, Linn Salto Mamsen, Claus Yding Andersen   +7 more
wiley   +1 more source