Results 71 to 80 of about 5,745 (171)
Journal of Inborn Errors of Metabolism and Screening, 2015 Mucopolysaccharidosis IVA (MPS IVA; Morquio A syndrome) is a lysosomal storage disorder caused by a deficient N-acetylgalactosamine-6-sulfate sulfatase activity, leading to cellular storage of undegraded keratan sulfate.
Guilherme Baldo PhD +6 more
doaj +1 more source
Isoforms of corneal keratan sulfate proteoglycan.
Journal of Biological Chemistry, 1990 Bovine corneal keratan sulfate proteoglycan was found to contain three major protein components. Two proteins (37 and 25 kDa) were released from the proteoglycan by endo-beta-galactosidase, N-glycanase, or chemical deglycosylation. A smaller protein (20 kDa), not covalently linked to keratan sulfate, co-purified with the proteoglycan by conventional ...
J L, Funderburgh, G W, Conrad
openaire +2 more sources
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Macular corneal dystrophy with isolated peripheral Descemet membrane deposits
American Journal of Ophthalmology Case Reports, 2019 Purpose: Macular Corneal Dystrophy (MCD, MIM #217800) is a category 1 corneal stromal dystrophy as per the current IC3D classification. While characterized by macular stromal deposits, we report a case of MCD type II with isolated bilateral peripheral ...
Wenlin Zhang +6 more
doaj +1 more source
Capillary endothelial cell heterogeneity in skeletal muscle of female and male mice
Physiological Reports, Volume 14, Issue 14, July 2026.Abstract In skeletal muscle, capillaries have been shown to be critical to active hyperemia by sensing skeletal muscle activity and directing blood flow to contracting muscle fibers. There is evidence to suggest that capillary endothelial cell (EC) characteristics may change along the length of a capillary.
Mackenzie E. Charter, Coral L. Murrant
wiley +1 more source
MedComm, Volume 7, Issue 6, June 2026.A novel, chemically synthesized fibromodulin (FMOD)‐derived peptide, SLI‐F06, has been developed to significantly improve scar appearance, tensile strength, and histological outcomes among multiple preclinical animal models. Demonstrating no genotoxicity or systemic/local toxicity, SLI‐F06 has received United States Food and Drug Administration ...
Zhong Zheng +9 more
wiley +1 more source
Arthritis Research & Therapy, 2017 Background We aimed to determine whether synovial fluid (SF) biomarkers can predict the progression of articular cartilage damage as determined by arthroscopic evaluation during and after anterior cruciate ligament (ACL) reconstruction.
Yasumori Sobue +6 more
doaj +1 more source
The Linkage Region of Cartilage Keratan Sulfate to Protein
Journal of Biological Chemistry, 1974 Abstract Glycopeptides derived from bovine nasal septum keratan sulfate by acid hydrolysis and gel chromatography are shown to be enriched in the carbohydrate-protein linkage region. The effects of alkali on these glycopeptides are compared to the effects on the starting material.
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Glycosaminoglycans and Proteoglycans
Pharmaceuticals, 2018 In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and Proteoglycans” we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan,
Vitor H. Pomin, Barbara Mulloy
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Integration of clinical data with a genome‐scale metabolic model of the human adipocyte
Molecular Systems Biology, 2013 We evaluated the presence/absence of proteins encoded by 14 077 genes in adipocytes obtained from different tissue samples using immunohistochemistry. By combining this with previously published adipocyte‐specific proteome data, we identified proteins ...
Adil Mardinoglu +10 more
doaj +1 more source