Long-term effects of hydrogen sulfide on the anabolic-catabolic balance of articular cartilage in vitro [PDF]
, 2017 [Abstract] Healthy cartilage maintenance relies on an equilibrium among the anabolic and catabolic processes in chondrocytes. With the onset of osteoarthritis (OA), increased interleukin (IL)-1β levels induce an inhibition of the synthesis of ...
Blanco García, Francisco J +7 more
core +2 more sources
The metabolism of 2‐fluoro‐2‐deoxy‐
, 1994 Gönna Fedders +3 more
openalex +1 more source
Glycosaminoglycans and Proteoglycans
Pharmaceuticals, 2018 In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and Proteoglycans” we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan,
Vitor H. Pomin, Barbara Mulloy
doaj +1 more source
Journal of Biological Chemistry, 2013 Background: Knowledge regarding UDP-N-acetylglucosamine transporter (NGT; SLC35A3) is incomplete due to the lack of NGT-deficient model cell lines. Results: The siRNA approach showed that NGT silencing reduces branching of complex N-glycans and keratan ...
Dorota Maszczak-Seneczko +5 more
semanticscholar +1 more source
Integration of clinical data with a genome‐scale metabolic model of the human adipocyte
Molecular Systems Biology, 2013 We evaluated the presence/absence of proteins encoded by 14 077 genes in adipocytes obtained from different tissue samples using immunohistochemistry. By combining this with previously published adipocyte‐specific proteome data, we identified proteins ...
Adil Mardinoglu +10 more
doaj +1 more source
Diagnostic Pathology, 2011 Mucopolysaccharidosis type IVA or Morquio A syndrome is characterized by the lack of N-acetylgalactosamine-6-sulfate-sulfatase and the accumulation of keratan sulfate and chondroitin-6-sulfate in the lysosomes.
Chkioua Latifa +4 more
doaj +1 more source
A diastrophic dysplasia sulfate transporter (SLC26A2) mutant mouse: morphological and biochemical characterization of the resulting chondrodysplasia phenotype [PDF]
, 2017 Mutations in the diastrophic dysplasia sulfate transporter (DTDST or SLC26A2) cause a family of recessively inherited chondrodysplasias including, in order of decreasing severity, achondrogenesis 1B, atelosteogenesis 2, diastrophic dysplasia (DTD) and ...
Bonafè, Luisa +11 more
core
Immunolocalization of Keratan Sulfate Proteoglycan in Rat Calvaria.
Archives of Histology and Cytology, 2001 We investigate, by the immunogold method, the localization of keratan sulfate (KS) proteoglycan in rat calvaria in order to clarify the detailed process of intramembranous ossification. KS was localized in bone nodules corresponding to calcified nodules, close to the saggital suture of calvaria. The immunoreactivity decreased in fully calcified regions
H, Nakamura +3 more
openaire +3 more sources
Keratan Sulfate Synthesis by Corneal Stromal Cells within Three-Dimensional Collagen Gel Cultures [PDF]
, 1996 Kiyoshi Nakazawa +4 more
openalex +1 more source
Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata. [PDF]
Mar Drugs, 2023 Chen R +7 more
europepmc +1 more source