A review on an imperative by-product: Glycosaminoglycans- A holistic approach
Glycosaminoglycan is a generic term for a class of minor but significant components of the body. The extraction, application, and functionalization of GAGs are essential to explore owing to their biological significance.
Bindia Sahu +4 more
doaj +1 more source
An improved method for the structural profiling of keratan sulfates: analysis of keratan sulfates from brain and ovarian tumors [PDF]
A previously developed method for the structural fingerprinting of keratan sulfates (Brown et al., Glycobiology, 5, 311-317, 1995) has been adapted for use with oligosaccharides fluorescently labeled with 2-aminobenzoic acid following keratanase II digestion.
Whitham, K. M. +5 more
openaire +2 more sources
Glycan Node Analysis of Plasma-Derived Extracellular Vesicles
Blood plasma is a readily accessible source of extracellular vesicles (EVs), i.e., cell-secreted nanosized carriers that contain various biomolecules, including glycans.
Sierra A. Walker +6 more
doaj +1 more source
Proteomic and Postproteomic Characterization of Keratan Sulfate-Glycanated Isoforms of Thyroglobulin and Transferrin Uniquely Elaborated by Papillary Thyroid Carcinomas. [PDF]
Previous studies have suggested that surface components of papillary thyroid carcinoma (PTC) cells may be aberrantly glycanated, but the precise nature of these molecules has not been unveiled nor documented to be of clinical relevance.
Colombatti, Alfonso +39 more
core +1 more source
Corneal Dermatopontin Interacts with Keratan Sulfate Proteoglycans
Dermatopontin is an extracellular matrix protein with many functions, amongst which is the involvement in collagen fibrils’ organization. It has been isolated from bovine corneal stroma, alone and in a complex with keratan sulfate proteoglycans, using 7
Follwood, N.I. +6 more
core +1 more source
Effect of epithelial debridement on human cornea proteoglycans
Corneal transparency is attributed to the regular spacing and diameter of collagen fibrils, and proteoglycans may play a role in fibrillogenesis and matrix assembly. Corneal scar tissue is opaque and this opacity is explained by decreased ultrastructural
E.S. Soriano +3 more
doaj +1 more source
Mucopolysaccharidoses (MPS) are a group of inherited lysosomal storage disorders caused by deficient levels and/or activity of glycosaminoglycan (GAG)-degradative enzymes.
Faizal Z. Asumda +6 more
doaj +1 more source
Novel Insight Into Glycosaminoglycan Biosynthesis Based on Gene Expression Profiles
Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, heparan sulfate, and keratan sulfate, except for hyaluronan that is a free polysaccharide, are covalently attached to core proteins to form proteoglycans.
Yi-Fan Huang +2 more
doaj +1 more source
Isolation and characterization of a heptaglycosylceramide from bovine erythrocyte membranes.
A heptaglycosylceramide was isolated from bovine erythrocyte membranes. The structure was characterized to be Gal(alpha 1-3)Gal(beta 1-4)GlcNAc(beta1-3)Gal(beta 1-4)Glc-NAc(beta 1-4)al(beta 1-4)GlcCer.
J L Chien, S C Li, Y T Li
doaj +1 more source
Endothelial glycocalyx degradation during sepsis: Causes and consequences
The glycocalyx is a ubiquitous structure found on endothelial cells that extends into the vascular lumen. It is enriched in proteoglycans, which are proteins attached to the glycosaminoglycans heparan sulfate, chondroitin sulfate, dermatan sulfate ...
Ryan C. Sullivan +3 more
doaj +1 more source

