Results 31 to 40 of about 6,637 (212)
Imaging keratan sulfate in ocular tissue sections by immunofluorescence microscopy and LA-ICP-MS
, 2022 Carbohydrate-specific antibodies can serve as valuable tools to monitor alterations in the extracellular matrix resulting from pathologies. Here, the keratan sulfate-specific monoclonal antibody MZ15 was characterized in more detail by immunofluorescence
Dernedde, J. +16 more
core +2 more sources
Increased Urinary Excretion of Keratan Sulfate in Fucosidosis [PDF]
Clinical Chemistry and Laboratory Medicine, 1978 In two children exhibiting the clinical symptoms of fucosidosis, the diagnosis was biochemically ascertained by the demonstration of a profound altpha-L-fucosidase deficiency in cultured skin fibroblasts. The non-dialysed urines of these fucosidosis patients were separated into two fractions by chromatography on Biogel P-2.
Greiling, H. +3 more
openaire +2 more sources
Journal of Biological Chemistry, 1975 A glycosidase which attacks corneal keratan sulfate was purified from extracts of Pseudomonas sp. IFO-13309. When corneal keratan sulfate was degraded by the purified enzyme, Sephadex G-50 chromatography indicated the presence of a number of oligosaccharides differing in size and sulfate content.
K, Nakazawa, S, Suzuki
openaire +2 more sources
Establishment of Glycosaminoglycan Assays for Mucopolysaccharidoses
Metabolites, 2014 Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders caused by deficiency of the lysosomal enzymes essential for catabolism of glycosaminoglycans (GAGs).
Shunji Tomatsu +13 more
doaj +1 more source
Journal of Biological Chemistry, 1972 Abstract Protein-keratan sulfate core was isolated from bovine nasal cartilage proteoglycan after enzymatically removing chondroitin sulfate with chondroitinase AC from Flavobacterium heparinum. The core preparation exhibited a broad, approximately Gaussian distribution of buoyant densities in CsCl density gradients (between 1.43 and 1.58 g per ml with
V C, Hascall, R L, Riolo
openaire +2 more sources
Proton conductivity of glycosaminoglycans.
PLoS ONE, 2019 Proton conductivity is important in many natural phenomena including oxidative phosphorylation in mitochondria and archaea, uncoupling membrane potentials by the antibiotic Gramicidin, and proton actuated bioluminescence in dinoflagellate.
John Selberg, Manping Jia, Marco Rolandi
doaj +1 more source
Collagens and proteoglycans of the corneal extracellular matrix
Brazilian Journal of Medical and Biological Research, 2003 The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with ...
Y.M. Michelacci
doaj +1 more source
Characterization and Determination of Human Urinary Keratan Sulfate.
Chemical and Pharmaceutical Bulletin, 1998 Keratan sulfate was isolated from normal human urine and was characterized by sugar compositional analysis and H-NMR spectroscopy. It was found that KS from human urine is classified as skeletal type (KS-II type chain) with an O-glycosidic linkage between galactosamine and serine (or threonine).
TOYODA, Hidenao +5 more
openaire +3 more sources
Sulodexide. Nephroprotective properties and horizons for use in nephrology
Медицинский совет, 2015 Sulodexide belongs to the class of glycosaminoglycans (GAGs) or mucopolysaccharides. Found in mammalian tissuesm, GAGs regulate the activity of a wide range of proteins (including chemokines, cytokines, growth factors, enzymes, morphogens, and adhesion ...
M. M. Batyushin
doaj +1 more source
Journal of Craniovertebral Junction and Spine, 2020 Morquio syndrome (MS) is an autosomal recessive defect caused by the deficiency of N-acetylgalactosamine-6-sulfatase. Odontoid hypoplasia, periodontoid soft tissue deposition, and cervical stenosis lead to myelopathy and quadriparesis in these patients ...
Suyash Singh +4 more
doaj +1 more source