Results 161 to 170 of about 182,642 (309)

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

UVB Upregulates Inflammatory Cytokines in Rosacea Cell Model by Promoting the Expression of TRPVs and TLR2. [PDF]

Immunotargets Ther
Xie Y, Hu Y, Huang J, Liu J, Zhang Q.
europepmc   +1 more source

Wound Repair Using PVA–CA Electrospun Dressings and Cold Plasma In Vivo

Journal of Applied Polymer Science, EarlyView.
In vivo wound healing evaluation of different treatments in a murine excisional wound model. (a) Representative photographs of wound closure at 3, 7, and 14 days post‐treatment for the different groups: Control, PVA‐CA, PVA‐CA‐Ag, NTP, PVA‐CA‐NTP, and PVA‐CA‐Ag‐NTP. (b) Experimental design showing six treatment groups with n = 18 wounds per group.
Jonalba M. Pereira, Emilia A. L. S. Arisawa, Antônio L. M. Maia‐Filho, José F. Silva, Nicoly Alves, Carolina H. da‐Silveira, Lucia Vieira   +6 more
wiley   +1 more source

Postbiotics and Nicotinamide Utilize Distinct Mechanisms to Improve Skin Barrier Integrity, Inflammation, and Keratinocyte Differentiation. [PDF]

Allergy
Pat Y, Yazici D, Babayev H, Ardicli S, Bu X, Simmons S, Almada A, Avena C, Jensen T, Dhir R, Westermann P, Garcia-Sanchez A, Li M, Ardicli O, Zeyneloglu C, Pane M, Amoruso A, Messner C, Ogulur I, Mitamura Y, Akdis M, Akdis CA.   +21 more
europepmc   +1 more source

Histone H3K27 Demethylase JMJD3 in Cooperation with NF-κB Regulates Keratinocyte Wound Healing.

Journal of Investigative Dermatology, 2016
Jungtae Na, Kwanghyun Lee, Wonho Na, J. Shin, Min-Jung Lee, T. Yune, H. Lee, Han-Sung Jung, Won‐Sun Kim, B. Ju   +9 more
semanticscholar   +1 more source

Linezolid‐mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition

Arthritis &Rheumatology, EarlyView.
Objective Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Because mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H. W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

A transitional desmosome/tonofibril network may relay mechanical strain to epidermal nerve terminals with high fidelity and sensitivity in the Cuban crocodile (<i>Crocodylus rhombifer)</i>: an ultrastructural study. [PDF]

Front Cell Dev Biol
Melkersson KG, Hodik M, Staxäng K, Hakizimana P, Li H, Rask-Andersen H.   +5 more
europepmc   +1 more source

Long Non‐Coding RNA H19 mediates STAT3 dependent activation of keratinocytes and fibroblasts in Systemic Sclerosis skin

Arthritis &Rheumatology, Accepted Article.
Objective Dermal Systemic Sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with lncRNA H19 (H19) highlighted as the most upregulated RNA in their cargo compared to healthy control (HC). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz, Christopher W Wasson, Rebecca L Ross, Francesco Del Galdo   +3 more
wiley   +1 more source

Mfsd2a is important for maintaining epidermal homeostasis. [PDF]

Proc Natl Acad Sci U S A
Wong BH, Mishra K, Chin CF, Galam DLA, Tan BC, Ding M, Torta F, Behmoaras J, Chua AWC, Silver DL.   +9 more
europepmc   +1 more source

MicroRNA-31 Promotes Skin Wound Healing by Enhancing Keratinocyte Proliferation and Migration.

Journal of Investigative Dermatology, 2015
Dongqing Li, Xi Li, Aoxue Wang, Aoxue Wang, F. Meisgen, A. Pivarcsi, E. Sonkoly, M. Ståhle, N. Landén   +8 more
semanticscholar   +1 more source