Results 51 to 60 of about 182,642 (309)

Role of autophagy during cutaneous wound healing in mice

Di-san junyi daxue xuebao, 2019
Objective To observe the dynamic changes in autophagy during cutaneous wound healing and investigate its possible contributions to wound repair. Methods Two skin wound of 6 mm in size were inflicted on the back of GFP-LC3 transgenic mice.
ZHAO Na, LIU Dengqun, WANG Guojian, LONG Shuang, WAN Huimin, SU Yongping, WANG Tao   +6 more
doaj   +1 more source

A protective Langerhans cell–keratinocyte axis that is dysfunctional in photosensitivity

Science Translational Medicine, 2018
Langerhans cells limit ultraviolet radiation–induced keratinocyte apoptosis and skin injury, and this axis is dysfunctional in lupus photosensitivity. Abrogating keratinocyte apoptosis in lupus Lupus patients can experience photosensitivity as manifested
W. Shipman, Susan Chyou, A. Ramanathan, P. M. Izmirly, Sneh Sharma, T. Pannellini, Dragos C. Dasoveanu, Xiaoping Qing, C. Magro, R. Granstein, M. Lowes, E. Pamer, D. Kaplan, J. Salmon, B. Mehrara, James W. Young, R. Clancy, C. Blobel, T. Lu   +18 more
semanticscholar   +1 more source

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

Keratinocyte Binding Assay Identifies Anti-Desmosomal Pemphigus Antibodies Where Other Tests Are Negative

Frontiers in Immunology, 2018
The serological diagnosis of pemphigus relies on the detection of IgG autoantibodies directed against the epithelial cell surface by indirect immunofluorescence (IIF) on monkey esophagus and against desmoglein 1 (Dsg1) and Dsg3 by ELISA.
Federica Giurdanella, Albertine M. Nijenhuis, Gilles F. H. Diercks, Marcel F. Jonkman, Hendri H. Pas   +4 more
doaj   +1 more source

Adverse Effect of Blue Light on DNA Integrity Is Accelerated by 5-Aminolevulinic Acid in HaCaT Human Keratinocyte Cells and B16F1 Murine Melanoma Cells

Biology, 2022
Several studies have suggested the potential benefits of 5-aminolevulinic acid (5-ALA)-based photodynamic therapy (PDT). 5-ALA is a precursor of heme, which generates reactive oxygen species (ROS) following photoirradiation.
Taiki Sato, Kazuomi Sato
doaj   +1 more source

H19 lncRNA regulates keratinocyte differentiation by targeting miR-130b-3p

Cell Death and Disease, 2017
Aberrant differentiation of keratinocytes has been demonstrated to be associated with a number of skin diseases. A growing number of studies have showed that long noncoding RNAs (lncRNAs) have an important part in gene regulation, however, the role of ...
Chun-Xiao Li, Hua-Guo Li, Linting Huang, Yu-wei Kong, Fuying Chen, Jian-yin Liang, Hong Yu, Z. Yao   +7 more
semanticscholar   +1 more source

Broadband, Flexible, Skin‐Compatible Carbon Dots/Graphene Photodetectors for Wearable Applications

Advanced Functional Materials, EarlyView.
Broadband, flexible photodetectors integrating nitrogen‐rich carbon dots with single‐layer graphene on plastic substrates are demonstrated. A biocompatible chitosan–glycerol electrolyte enables efficient low‐voltage gating and on‐skin operation. The devices exhibit ultraviolet‐to‐near‐infrared response, mechanical robustness under bending, and verified
Nouha Loudhaief, Petr Rozhin, Ilaria Bertuol, Ali Raza, Leonardo Viti, Subhankar Roy, Enrico Cavarzerani, Luca Sbuelz, Matteo Brilli, Andrea Serinolli, Jacopo Nicoletti, Riccardo Piccoli, Sebastián Castilla, Simone Dal Zilio, Enrique Rodríguez‐Castellón, Miriam Serena Vitiello, Maurizio Selva, Flavio Rizzolio, Alvise Perosa, Giovanni Antonio Salvatore, Domenico De Fazio   +20 more
wiley   +1 more source

miR-21 Promotes Keratinocyte Migration and Re-epithelialization During Wound Healing

International Journal of Biological Sciences, 2011
MicroRNAs involved in keratinocyte migration and wound healing are largely unknown. Here, we revealed the indispensable role of miR-21 in keratinocyte migration and in re-epithelialization during wound healing in mice.
Xue Yang, Jun Wang, Shui-Long Guo, Kai-Ji Fan, Jun Li, You-Liang Wang, Yan Teng, Xiao Yang
doaj  

Effect of Different Collection Times of Dermal Fibroblast Conditioned Medium (DFCM) on In Vitro Re-Epithelialisation Process

Biomedicines, 2022
A key event in wound healing is re-epithelialisation, which is mainly regulated via paracrine signalling of cytokines, chemokines, and growth factors secreted by fibroblasts.
Nurul ‘Izzah Abdul Ghani, Rabiatul Adawiyah Razali, Shiplu Roy Chowdhury, Mh Busra Fauzi, Aminuddin Bin Saim, Binti Haji Idrus Ruszymah, Manira Maarof   +6 more
doaj   +1 more source

AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production

Journal of Investigative Dermatology, 2016
Prominent skin involvement is a defining characteristic of autoinflammatory disorders caused by abnormal IL-1 signaling. However, the pathways and cell types that drive cutaneous autoinflammatory features remain poorly understood.
S. Mahil, S. Twelves, K. Farkas, N. Setta-Kaffetzi, A. Burden, J. Gach, A. Irvine, László Képíró, M. Mockenhaupt, H. Oon, J. Pinner, A. Ranki, M. Seyger, P. Soler-Palacín, E. Storan, E. Tan, L. Valeyrie‐Allanore, H. Young, R. Trembath, S. Choon, M. Széll, Z. Bata-Csorgo, Catherine H. Smith, P. Di Meglio, J. Barker, F. Capon   +25 more
semanticscholar   +1 more source