Results 41 to 50 of about 222,067 (306)

The time-dependent expression of keratins 5 and 13 during the reepithelialization of human skin wounds [PDF]

, 1993
The time-dependent reepithelialization of 55 human surgical skin wounds with a wound age between 8h and more than 2 months was investigated by the immunohistochemical localization of cytokeratins 5 and 13.
A. Nerlich, D Cooper, D Cooper, D Mischke, EJ O'Keefe, G Gabbiani, GD Winter, GNP Muijen van, J-P Ortonne, J. Tübel, JL Cordell, JN Mansbridge, LJ Ordman, M Guo, P Betz, P. Betz, R Moll, R Moll, R. Penning, RAF Clark, SC Pang, SM Hsu, SV Pollack, TT Sun, W Oehlert, W. Eisenmenger   +25 more
core   +1 more source

Keratinocyte Growth Factor Promotes Melanosome Transfer to Keratinocytes [PDF]

Journal of Investigative Dermatology, 2005
Melanogenesis and melanosome transfer from the melanocytes to the neighboring keratinocytes are induced by ultraviolet radiation and modulated by autocrine and paracrine factors. Keratinocyte growth factor (KGF/fibroblast growth factor (FGF)7) is a paracrine mediator of human keratinocyte growth and differentiation. We evaluated the influence of KGF on
CARDINALI G, CECCARELLI, SIMONA, KOVACS D, ASPITE N, LOTTI, Lavinia Vittoria, TORRISI, Maria Rosaria, PICARDO M.   +6 more
openaire   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

The Epidermis in Microgravity and Unloading Conditions and Their Effects on Wound Healing

Frontiers in Bioengineering and Biotechnology, 2022
The future objectives of human space flight are changing from low-term permanence in the International Space Station to missions beyond low Earth orbit to explore other planets.
Stefano Bacci, Stefano Bacci, Daniele Bani, Daniele Bani   +3 more
doaj   +1 more source

Keratinocytes from human skin respond as typical immune cells after the stimulation with _Trichophyton rubrum_ [PDF]

, 2007
_Trichophyton rubrum_ is the main agent causing dermatophytosis (1). Keratinocytes are considered to be the first physical barrier of defense against pathogens (2). But not only a physical barrier.
Alfonso E. Islas-Rodrí, Luz A. Garcí   +1 more
core   +1 more source

HLA-G: expression in human keratinocytes in vitro and in human skin in vivo [PDF]

, 1994
Classical, polymorphic major histocompatibility complex class I molecules are expressed on most nucleated cells.They present peptides at the cell surface and, thus, enable the immune system to scan peptides for their antigenicity.
Ulbrecht, M., Rehberger, B., Strobel, I., Messer, Gerald, Kind, P., Degitz, K., Bieber, T., Weiss, Elisabeth H.   +7 more
core   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Cutaneous lupus erythematosus: insights from molecular pathogenesis to targeted therapies [PDF]

Exploration of Immunology
Cutaneous lupus erythematosus (CLE) is the most common organ manifestation in individuals diagnosed with systemic lupus erythematosus (SLE). CLE can occur either alone or in association with SLE; in the latter case, it substantially increases the ...
Fatima K. Alduraibi, Josh Goldsmith, Peter C. Chien   +2 more
doaj   +1 more source

Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin [PDF]

, 2002
The squamous stratified epithelia contain a proliferative (harboring mitotic activity) and a differentiating compartment. Due to the potential of protein-carbohyd rate interactions to regulate cellular activities we introduced a mammalian lectin to cyto-
Dvorankova, Barbora, Gabius, Hans-Joachim, Hercogová, Jana, Holíkova, Zuzana, Kaltner, Herbert, Motlik, Jan, Plzák, Jan, Smetana, Karel   +7 more
core   +1 more source

Platelet-derived transforming growth factor-β1 promotes keratinocyte proliferation in cutaneous wound healing. [PDF]

, 2020
Platelets are a recognised potent source of transforming growth factor-β1 (TGFβ1), a cytokine known to promote wound healing and regeneration by stimulating dermal fibroblast proliferation and extracellular matrix deposition.
Chong, DLW, Holmes, AM, Hughes, S, Labelle, M, Porter, JC, Rodriguez-Justo, M, Scotton, CJ, Trinder, S   +7 more
core   +3 more sources