Results 21 to 30 of about 6,827 (117)

In vitro Effect of Geranylgeraniol (GGOH) on Bisphosphonate-Induced Cytotoxicity of Oral Mucosa Cells

Frontiers in Oral Health, 2022
Medication-related osteonecrosis of the jaw (MRONJ) is an often-severe complication found in patients receiving bisphosphonates in the management of Paget's, osteoporosis and metastatic bone cancer.
Krit Rattanawonsakul, George Bullock, Robert Bolt, Frederik Claeyssens, Simon Atkins, Vanessa Hearnden   +5 more
doaj   +1 more source

Role of Keratinocytes in Sensitive Skin

Frontiers in Medicine, 2019
Sensitive skin is a clinical syndrome defined by the occurrence of unpleasant sensations such as burning, stinging, tingling, pricking, or itching in response to various normally innocuous physical, chemical, and thermal stimuli.
Matthieu Talagas, Matthieu Talagas, Laurent Misery, Laurent Misery   +3 more
doaj   +1 more source

Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities

PAIN Reports, 2016
. Introduction: Epidermal keratinocytes are increasingly recognized as active participants in the sensory transduction of itch and pain, processes known to involve primary afferent glutamatergic neurons.
David Cabañero, Takeshi Irie, Marta Celorrio, Christopher Trousdale, David M. Owens, David Virley, Phillip J. Albrecht, Michael J. Caterina, Frank L. Rice, Jose A. Morón   +9 more
doaj   +1 more source

Beneficial Effects of Young Coconut Juice on Increasing Skin Thickness, Enhancing Skin Whitening, and Reducing Skin Wrinkles in Ovariectomized Rats

Applied Sciences, 2022
It has been previously demonstrated in light microscopic and immunohistochemical studies that ovariectomized rats receiving young coconut juice at 100 mL/kg BW showed much better wound healing and improved skin complexion. Nevertheless, it was found that
Nisaudah Radenahmad, Amornpun Sereemaspun, Nurdeen Bueraheng, Albert Manggading Hutapea   +3 more
doaj   +1 more source

Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?

Cells, 2022
Pemphigus vulgaris is an autoimmune blistering disease of the epidermis, caused by autoantibodies against desmosomal proteins, mainly desmogleins 1 and 3, which induce an impairment of desmosomal adhesion and blister formation. Recent findings have shown
Anna Zakrzewicz, Celina Würth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen, Vladimir Bobkov, Ritva Tikkanen   +10 more
doaj   +1 more source

Osmotic Stress Interferes with DNA Damage Response and H2AX Phosphorylation in Human Keratinocytes

Cells, 2022
The human skin and in particular its outermost layer, the epidermis, protects the body from potentially harmful substances, radiation as well as excessive water loss.
Laura Hoen, Christoph Rudisch, Michael Wick, Daniela Indenbirken, Adam Grundhoff, Florian Wegwitz, Stefan Kalkhof, Janosch Hildebrand   +7 more
doaj   +1 more source

Persistent proliferation of keratinocytes and prolonged expression of pronociceptive inflammatory mediators might be associated with the postoperative pain in KK mice

Molecular Pain, 2020
Epidermal keratinocytes play a vital role in restoration of the intact skin barrier during wound healing. The negative effect of hyperglycemia may prolong the wound healing process.
Ruijuan Guo, Junqiang Hao, Danxu Ma, Huili Li, Kaihua Liao, Yun Wang   +5 more
doaj   +1 more source

Mammalian Epidermis: A Compendium of Lipid Functionality

Frontiers in Physiology, 2022
Mammalian epidermis is a striking example of the role of lipids in tissue biology. In this stratified epithelium, highly specialized structures are formed that leverage the hydrophobic properties of lipids to form an impermeable barrier and protect the ...
Matteo Vietri Rudan, Fiona M. Watt
doaj   +1 more source

EpCAM Induction Functionally Links to the Wnt-Enhanced Cell Proliferation in Human Keratinocytes

Cell Transplantation, 2014
Accelerating proliferation of primary keratinocytes benefits skin autografts for severely burned patients. Wnt signal, a conserved pathway controlling cell cycle and morphogenesis in embryo, also involves in cell proliferation and tumorigenesis in adult ...
Ching-I Shen, Hsiu-Chin Lee, Ying-Hsien Kao, Chieh-Shan Wu, Po-Hung Chen, Shinn-Zong Lin, Ping-Shan Lai, Hong-Lin Su   +7 more
doaj   +1 more source

Cell Transformation and the Evolution of a Field of Precancerization As It Relates to Oral Leukoplakia

International Journal of Dentistry, 2011
Potentially malignant oral leukoplakias arise within precancerized epithelial fields consisting of cytogenetically altered keratinocytes at various stages of transformation.
L. Feller, J. Lemmer
doaj   +1 more source