Results 21 to 30 of about 163,612 (298)

Functional characterization of cultured keratinocytes after acute cutaneous burn injury. [PDF]

, 2012
In addition to forming the epithelial barrier against the outside environment keratinocytes are immunologically active cells. In the treatment of severely burned skin, cryoconserved keratinocyte allografts gain in importance.
Gerd G Gauglitz, Faist Eugen, Guido Henkel von Donnersmarck, Eugen Faist, v. Spiegel Felix, Spiegel, Felix von, Faist, Eugen, Zedler Siegfried, Siegfried Zedler, Felix von Spiegel, v. Donnersmarck Guido Henkel, Fuhr, Jasmin, Jasmin Fuhr, Gauglitz, Gerd, Henkel von Donnersmarck, Guido, Fuhr Jasmin, Zedler, Siegfried, Gauglitz Gerd G.   +17 more
core   +2 more sources

Persistent proliferation of keratinocytes and prolonged expression of pronociceptive inflammatory mediators might be associated with the postoperative pain in KK mice

Molecular Pain, 2020
Epidermal keratinocytes play a vital role in restoration of the intact skin barrier during wound healing. The negative effect of hyperglycemia may prolong the wound healing process.
Ruijuan Guo, Junqiang Hao, Danxu Ma, Huili Li, Kaihua Liao, Yun Wang   +5 more
doaj   +1 more source

Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?

Cells, 2022
Pemphigus vulgaris is an autoimmune blistering disease of the epidermis, caused by autoantibodies against desmosomal proteins, mainly desmogleins 1 and 3, which induce an impairment of desmosomal adhesion and blister formation. Recent findings have shown
Anna Zakrzewicz, Celina Würth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen, Vladimir Bobkov, Ritva Tikkanen   +10 more
doaj   +1 more source

Osmotic Stress Interferes with DNA Damage Response and H2AX Phosphorylation in Human Keratinocytes

Cells, 2022
The human skin and in particular its outermost layer, the epidermis, protects the body from potentially harmful substances, radiation as well as excessive water loss.
Laura Hoen, Christoph Rudisch, Michael Wick, Daniela Indenbirken, Adam Grundhoff, Florian Wegwitz, Stefan Kalkhof, Janosch Hildebrand   +7 more
doaj   +1 more source

Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]

, 2011
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu, Frazer J. Rixon, Petermann, P., Rixon Frazer J., Rahn, E., Hsu Mei-Ju, Knebel-Mörsdorf, D., Geraghty, R.J., Dagmar Knebel-Mörsdorf, Rahn Elena, Philipp Petermann, Knebel-Mörsdorf Dagmar, Elena Rahn, Frazer J Rixon, Hsu, M.-J., Rixon, F.J., Petermann Philipp   +16 more
core   +1 more source

Mammalian Epidermis: A Compendium of Lipid Functionality

Frontiers in Physiology, 2022
Mammalian epidermis is a striking example of the role of lipids in tissue biology. In this stratified epithelium, highly specialized structures are formed that leverage the hydrophobic properties of lipids to form an impermeable barrier and protect the ...
Matteo Vietri Rudan, Fiona M. Watt
doaj   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2-Mediated Glycolysis in Keratinocytes. [PDF]

Adv Sci (Weinh)
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Jiang X, Miao G, Shen N, Han Q, Han X, Qiao Z, Feng K, Tan Z, Wang Y, Liu X, Wu C, Yan Z.   +11 more
europepmc   +2 more sources

EpCAM Induction Functionally Links to the Wnt-Enhanced Cell Proliferation in Human Keratinocytes

Cell Transplantation, 2014
Accelerating proliferation of primary keratinocytes benefits skin autografts for severely burned patients. Wnt signal, a conserved pathway controlling cell cycle and morphogenesis in embryo, also involves in cell proliferation and tumorigenesis in adult ...
Ching-I Shen, Hsiu-Chin Lee, Ying-Hsien Kao, Chieh-Shan Wu, Po-Hung Chen, Shinn-Zong Lin, Ping-Shan Lai, Hong-Lin Su   +7 more
doaj   +1 more source

Cell Transformation and the Evolution of a Field of Precancerization As It Relates to Oral Leukoplakia

International Journal of Dentistry, 2011
Potentially malignant oral leukoplakias arise within precancerized epithelial fields consisting of cytogenetically altered keratinocytes at various stages of transformation.
L. Feller, J. Lemmer
doaj   +1 more source

Individual Keratinocyte Necroses in the Epidermis Are Apoptotic Keratinocytes in the Skin

Diagnostics, 2023
The patient was a 44-year-old woman with Stevens–Johnson syndrome due to receiving Baktar® (sulfamethoxazole trimethoprim) medication at our outpatient dermatology clinic. The epidermis, dermis, and subcutaneous adipose tissue samples showed numerous necrotic keratinocytes in the epidermis.
Mitsuhiro Tachibana, Hideki Hamayasu, Kazuki Tomita, Yuta Kage   +3 more
openaire   +3 more sources